Search Results - "Cai, Jiyang"
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Application of KOH-ethanol Solution in Separation of Waste Photovoltaic Panels
Published in Nature environment and pollution technology (01-03-2022)“…With the continuous development of photovoltaic panel technology in recent years, the frequency of replacement has accelerated, which has led to the continuous…”
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Essential Roles of the PI3 Kinase/Akt Pathway in Regulating Nrf2-Dependent Antioxidant Functions in the RPE
Published in Investigative ophthalmology & visual science (01-04-2008)“…To investigate functional interactions between the phosphatidylinositol 3-kinase (PI3K)/Akt pathway and the nuclear factor erythroid 2-related factor 2…”
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3
Protective Effects of Melatonin on Retinal Inflammation and Oxidative Stress in Experimental Diabetic Retinopathy
Published in Oxidative medicine and cellular longevity (01-01-2016)“…Oxidative stress and inflammation are important pathogenic factors contributing to the etiology of diabetic retinopathy (DR). Melatonin is an endogenous…”
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4
Age-related retinopathy in NRF2-deficient mice
Published in PloS one (29-04-2011)“…Cumulative oxidative damage is implicated in the pathogenesis of age-related macular degeneration (AMD). Nuclear factor erythroid 2-related factor 2 (NRF2) is…”
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Modulation of Oxidative Stress and Inflammation in the Aged Lacrimal Gland
Published in The American journal of pathology (01-02-2021)“…Inflammation and oxidative stress accompany aging. This study investigated the interplay between oxidative stress and inflammation in the lacrimal gland…”
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6
Outcomes of Congenital Zika Disease Depend on Timing of Infection and Maternal-Fetal Interferon Action
Published in Cell reports (Cambridge) (07-11-2017)“…Zika virus (ZIKV) infection during pregnancy in humans results in intrauterine growth restriction, spontaneous abortion, and microcephaly. Here, we found that…”
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Exosomal MiRNA Transfer between Retinal Microglia and RPE
Published in International journal of molecular sciences (17-05-2020)“…The retinal pigment epithelium (RPE), the outermost layer of the retina, provides essential support to both the neural retina and choroid. Additionally, the…”
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Biopolymer-based functional films for packaging applications: A review
Published in Frontiers in nutrition (Lausanne) (22-08-2022)“…Food packaging is a coordinated system comprising food processing, protection from contamination and adulteration, transportation and storage, and distribution…”
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Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis
Published in Frontiers in immunology (21-04-2021)“…Metformin is not only the first-line medication for the treatment of type 2 diabetes, but it is also effective as an anti-inflammatory, anti-oxidative and…”
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10
Methylmercury Toxicity and Nrf2-dependent Detoxification in Astrocytes
Published in Toxicological sciences (01-01-2009)“…Methylmercury (MeHg) is a potent neurotoxicant and preferentially induces oxidative injury in astrocytes. In neuronal tissues, nuclear factor erythroid…”
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Melatonin-mediated cytoprotection against hyperglycemic injury in Müller cells
Published in PloS one (04-12-2012)“…Oxidative stress is a contributing factor to the development and progression of diabetic retinopathy, a leading cause of blindness in people at working age…”
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Methylmercury Induces Acute Oxidative Stress, Altering Nrf2 Protein Level in Primary Microglial Cells
Published in Toxicological sciences (01-08-2010)“…The neurotoxicity of methylmercury (MeHg) is well documented in both humans and animals. MeHg causes acute and chronic damage to multiple organs, most…”
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13
Tunable glycyrrhizic acid supramolecular hydrogels via metal ion complexation
Published in Giant (Oxford, England) (01-03-2024)“…•Metal ion complexation tunes the rheology and network structure of GA hydrogels.•Monovalent metal ions at high concentrations induce a compact and ordered gel…”
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14
Formulation Stabilization and Disaggregation of Bevacizumab, Ranibizumab and Aflibercept in Dilute Solutions
Published in Pharmaceutical research (01-04-2018)“…Purpose Studies were conducted to investigate dilute solutions of the monoclonal antibody (mAb) bevacizumab, mAb fragment ranibizumab and fusion protein…”
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15
Choroidal γδ T cells in protection against retinal pigment epithelium and retinal injury
Published in The FASEB journal (01-11-2017)“…γδ T cells located near the epithelial barrier are integral components of local inflammatory and innate immune responses. We have previously reported the…”
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Polarized lung inflammation and Tie2/angiopoietin-mediated endothelial dysfunction during severe Orientia tsutsugamushi infection
Published in PLoS neglected tropical diseases (01-03-2020)“…Orientia tsutsugamushi infection can cause acute lung injury and high mortality in humans; however, the underlying mechanisms are unclear. Here, we tested a…”
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Increased Glutathione Synthesis through an ARE-Nrf2-Dependent Pathway by Zinc in the RPE: Implication for Protection against Oxidative Stress
Published in Investigative ophthalmology & visual science (01-06-2006)“…To determine the molecular mechanisms underlying the protective effects of zinc against oxidative stress in cultured retinal pigment epithelial (RPE) cells…”
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18
Role of autophagy in methylmercury-induced neurotoxicity in rat primary astrocytes
Published in Archives of toxicology (01-02-2016)“…Autophagy is an evolutionarily conserved process in which cytoplasmic proteins and organelles are degraded and recycled for reuse. There are numerous reports…”
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IL-22 hinders antiviral T cell responses and exacerbates ZIKV encephalitis in immunocompetent neonatal mice
Published in Journal of neuroinflammation (25-08-2020)“…The Zika virus (ZIKV) outbreak that occurred in multiple countries was linked to increased risk of nervous system injuries and congenital defects. However,…”
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Type 1-skewed neuroinflammation and vascular damage associated with Orientia tsutsugamushi infection in mice
Published in PLoS neglected tropical diseases (24-07-2017)“…Scrub typhus is a life-threatening disease, due to infection with O. tsutsugamushi, a Gram-negative bacterium that preferentially replicates in endothelial…”
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