Search Results - "Cai, Jianye"

A novel protein encoded by circFNDC3B inhibits tumor progression and EMT through regulating Snail in colon cancer by Pan, Zihao, Cai, Jianye, Lin, Jiatong, Zhou, Huinian, Peng, Jingwen, Liang, Jinliang, Xia, Long, Yin, Qi, Zou, Baojia, Zheng, Jun, Qiao, Liang, Zhang, Lei

“…Colon cancer (CC) is a common malignant cancer. Recently, circFNDC3B was found to exert biological function in multiple cancers. However, it was unclear…”
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Neutrophil to Lymphocyte Ratio and Platelet to Lymphocyte Ratio as Prognostic Predictors for Hepatocellular Carcinoma Patients with Various Treatments: a Meta-Analysis and Systematic Review by Zheng, Jun, Cai, Jianye, Li, Hui, Zeng, Kaining, He, Liying, Fu, Hongyuan, Zhang, Jiebin, Chen, Liang, Yao, Jia, Zhang, Yingcai, Yang, Yang

“…Background/Aims: Systemic inflammatory response (SIR) is widely considered as a preoperative risk factor for hepatocellular carcinoma (HCC) outcomes. The…”
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Cell adhesion-mediated mitochondria transfer contributes to mesenchymal stem cell-induced chemoresistance on T cell acute lymphoblastic leukemia cells by Wang, Jiancheng, Liu, Xin, Qiu, Yuan, Shi, Yue, Cai, Jianye, Wang, Boyan, Wei, Xiaoyue, Ke, Qiong, Sui, Xin, Wang, Yi, Huang, Yinong, Li, Hongyu, Wang, Tao, Lin, Ren, Liu, Qifa, Xiang, Andy Peng

“…Despite the high cure rate of T cell acute lymphoblastic leukemia (T-ALL), drug resistance to chemotherapy remains a significant clinical problem. Bone marrow…”
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Nestin regulates cellular redox homeostasis in lung cancer through the Keap1–Nrf2 feedback loop by Wang, Jiancheng, Lu, Qiying, Cai, Jianye, Wang, Yi, Lai, Xiaofan, Qiu, Yuan, Huang, Yinong, Ke, Qiong, Zhang, Yanan, Guan, Yuanjun, Wu, Haoxiang, Wang, Yuanyuan, Liu, Xin, Shi, Yue, Zhang, Kang, Wang, Maosheng, Peng Xiang, Andy

“…Abnormal cancer antioxidant capacity is considered as a potential mechanism of tumor malignancy. Modulation of oxidative stress status is emerging as an…”
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Transplantation of hPSC-derived pericyte-like cells promotes functional recovery in ischemic stroke mice by Sun, Jiaqi, Huang, Yinong, Gong, Jin, Wang, Jiancheng, Fan, Yubao, Cai, Jianye, Wang, Yi, Qiu, Yuan, Wei, Yili, Xiong, Chuanfeng, Chen, Jierui, Wang, Bin, Ma, Yuanchen, Huang, Lihua, Chen, Xiaoyong, Zheng, Shuwei, Huang, Weijun, Ke, Qiong, Wang, Tao, Li, Xiaoping, Zhang, Wei, Xiang, Andy Peng, Li, Weiqiang

“…Pericytes play essential roles in blood–brain barrier (BBB) integrity and dysfunction or degeneration of pericytes is implicated in a set of neurological…”
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MSCs ameliorate hepatocellular apoptosis mediated by PINK1-dependent mitophagy in liver ischemia/reperfusion injury through AMPKα activation by Zheng, Jun, Chen, Liang, Lu, Tongyu, Zhang, Yingcai, Sui, Xin, Li, Yang, Huang, Xuna, He, Liying, Cai, Jianye, Zhou, Chaorong, Liang, Jinliang, Chen, Guihua, Yao, Jia, Yang, Yang

“…Hepatocyte apoptosis is the main pathophysiological process underlying liver ischemia/reperfusion (I/R) injury. Mitochondrial abnormalities have a vital role…”
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Extracellular Vesicles Derived from Human Umbilical Cord Mesenchymal Stem Cells Protect Liver Ischemia/Reperfusion Injury by Reducing CD154 Expression on CD4+ T Cells via CCT2 by Zheng, Jun, Lu, Tongyu, Zhou, Chaorong, Cai, Jianye, Zhang, Xiaomei, Liang, Jinliang, Sui, Xin, Chen, Xiaoyan, Chen, Liang, Sun, Yao, Zhang, Jiebin, Chen, Wenjie, Zhang, Yingcai, Yao, Jia, Chen, Guihua, Yang, Yang

“…As a cause of postoperative complications and early hepatic failure after liver transplantation, liver ischemia/reperfusion injury (IRI) still has no effective…”
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Systemic Immune-Inflammation Index (SII) is Useful to Predict Survival Outcomes in Patients After Liver Transplantation for Hepatocellular Carcinoma within Hangzhou Criteria by Fu, Hongyuan, Zheng, Jun, Cai, Jianye, Zeng, Kaining, Yao, Jia, Chen, Liang, Li, Hui, Zhang, Jiebin, Zhang, Yingcai, Zhao, Hui, Yang, Yang

“…Background: There is growing evidence that the systemic immune-inflammation index (SII), a novel prognostic biomarker based on peripheral lymphocyte,…”
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Nestin-dependent mitochondria-ER contacts define stem Leydig cell differentiation to attenuate male reproductive ageing by Yao, Senyu, Wei, Xiaoyue, Deng, Wenrui, Wang, Boyan, Cai, Jianye, Huang, Yinong, Lai, Xiaofan, Qiu, Yuan, Wang, Yi, Guan, Yuanjun, Wang, Jiancheng

“…Male reproductive system ageing is closely associated with deficiency in testosterone production due to loss of functional Leydig cells, which are…”
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Nuclear Nestin deficiency drives tumor senescence via lamin A/C-dependent nuclear deformation by Zhang, Yanan, Wang, Jiancheng, Huang, Weijun, Cai, Jianye, Ba, Junhui, Wang, Yi, Ke, Qiong, Huang, Yinong, Liu, Xin, Qiu, Yuan, Lu, Qiying, Sui, Xin, Shi, Yue, Wang, Tao, Shen, Huiyong, Guan, Yuanjun, Zhou, Ying, Chen, Yuan, Wang, Maosheng, Xiang, Andy Peng

“…Emerging evidence has revealed that Nestin not only serves as a biomarker for multipotent stem cells, but also regulates cell proliferation and invasion in…”
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FTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC by Li, Rong, Yan, Xijing, Xiao, Cuicui, Wang, Tingting, Li, Xuejiao, Hu, Zhongying, Liang, Jinliang, Zhang, Jiebin, Cai, Jianye, Sui, Xin, Liu, Qiuli, Wu, Manli, Xiao, Jiaqi, Chen, Haitian, Liu, Yasong, Jiang, Chenhao, Lv, Guo, Chen, Guihua, Zhang, Yingcai, Yao, Jia, Zheng, Jun, Yang, Yang

“…Older livers are more prone to hepatic ischaemia/reperfusion injury (HIRI), which severely limits their utilization in liver transplantation. The potential…”
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Heat shock preconditioning mesenchymal stem cells attenuate acute lung injury via reducing NLRP3 inflammasome activation in macrophages by Lv, Haijin, Yuan, Xiaofeng, Zhang, Jiebin, Lu, Tongyu, Yao, Jia, Zheng, Jun, Cai, Jianye, Xiao, Jiaqi, Chen, Haitian, Xie, Shujuan, Ruan, Ying, An, Yuling, Sui, Xin, Yi, Huimin

“…Acute lung injury (ALI) remains a common cause of morbidity and mortality worldwide, and to date, there is no effective treatment for ALI. Previous studies…”
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Prognostic Value of the Glasgow Prognostic Score or Modified Glasgow Prognostic Score for Patients with Colorectal Cancer Receiving Various Treatments: a Systematic Review and Meta-Analysis by He, Liying, Li, Hui, Cai, Jianye, Chen, Liang, Yao, Jia, Zhang, Yingcai, Xu, Wanfu, Geng, Lanlan, Yang, Min, Chen, Peiyu, Zheng, Jun , Yang, Yang, Gong, Sitang

“…Background/Aims: Increasing evidence indicates that the systemic inflammatory response plays a vital role in carcinogenesis. The Glasgow Prognostic Score or…”
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CircFOXK2 promotes hepatocellular carcinoma progression and leads to a poor clinical prognosis via regulating the Warburg effect by Zheng, Jun, Yan, Xijing, Lu, Tongyu, Song, Wen, Li, Yang, Liang, Jinliang, Zhang, Jiebin, Cai, Jianye, Sui, Xin, Xiao, Jiaqi, Chen, Haitian, Chen, Guihua, Zhang, Qi, Liu, Yubin, Yang, Yang, Zheng, Kanghong, Pan, Zihao

“…The Warburg effect is well-established to be essential for tumor progression and accounts for the poor clinical outcomes of hepatocellular carcinoma (HCC)…”
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Chemotherapy combined with radiotherapy can benefit more unresectable HCC patients with portal and/or hepatic vein invasion: a retrospective analysis of the SEER database by Qiu, Xiaotong, Cai, Jianye, Chen, Haitian, Yao, Jia, Xiao, Cuicui, Li, Rong, Xiao, Jiaqi, Zhang, Jiebin, Sui, Xin, Lu, Tongyu, Zheng, Jun, Zhang, Yingcai, Yang, Yang

“…The purpose of this study is to evaluate the effects of chemotherapy and radiotherapy on the prognosis of unresectable HCC patients with portal and/or hepatic…”
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A novel MSC-based immune induction strategy for ABO-incompatible liver transplantation: a phase I/II randomized, open-label, controlled trial by Zhang, Yingcai, Zhang, Jiebin, Yi, Huimin, Zheng, Jun, Cai, Jianye, Chen, Wenjie, Lu, Tongyu, Chen, Liang, Du, Cong, Liu, Jianrong, Yao, Jia, Zhao, Hui, Wang, Guoying, Fu, Binsheng, Zhang, Tong, Zhang, Jian, Wang, Genshu, Li, Hua, Xiang, Andy Peng, Chen, Guihua, Yi, Shuhong, Zhang, Qi, Yang, Yang

“…ABO-incompatible liver transplantation (ABO-i LT) has become a rescue therapeutic option for patients with severe hepatic failure. Although the use of…”
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Mesenchymal stromal cells attenuate post-stroke infection by preventing caspase-1-dependent splenic marginal zone B cell death by Huang, Yinong, Wang, Jiancheng, Lai, Xiaofan, Qiu, Yuan, Cai, Jianye, Ma, Yuanchen, Liu, Yilin, Qiu, Wei, Lu, Zhengqi, Xiang, Andy Peng

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Inhibition of TGFβ improves hematopoietic stem cell niche and ameliorates cancer-related anemia by Wang, Boyan, Wang, Yi, Chen, Hainan, Yao, Senyu, Lai, Xiaofan, Qiu, Yuan, Cai, Jianye, Huang, Yinong, Wei, Xiaoyue, Guan, Yuanjun, Wang, Tao, Wang, Jiancheng, Xiang, Andy Peng

“…Cancer cachexia is a wasting syndrome that is quite common in terminal-stage cancer patients. Cancer-related anemia is one of the main features of cancer…”
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Administration of AG490 decreases the senescence of umbilical cord-mesenchymal stem cells and promotes the cytotherapeutic effect in liver fibrosis by Jiang, Chenhao, Chen, Huaxin, Kang, Yinqian, He, Xinyi, Huang, Jianyang, Lu, Tongyu, Sui, Xin, Chen, Haitian, Xiao, Jiaqi, Zhang, Jiebin, Zhang, Hanwen, Zheng, Jun, Yang, Yang, Yao, Jia, Cai, Jianye, Zhang, Yingcai

“…The therapeutic potential of umbilical cord-mesenchymal stem cell (UC-MSC) transplantation in liver fibrosis has been highlighted. However, the fate of…”
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Mesenchymal Stem Cell Membrane‐Camouflaged Liposomes for Biomimetic Delivery of Cyclosporine A for Hepatic Ischemia‐Reperfusion Injury Prevention by Chen, Haitian, Yin, Wen, Yao, Kang, Liang, Jinliang, Cai, Jianye, Sui, Xin, Zhao, Xuegang, Zhang, Jiebin, Xiao, Jiaqi, Li, Rong, Liu, Qiuli, Yao, Jia, You, Guohua, Liu, Yasong, Jiang, Chenhao, Qiu, Xiaotong, Wang, Tingting, You, Qiang, Zhang, Yingcai, Yang, Mo, Zheng, Jun, Dai, Zong, Yang, Yang

“…Hepatic ischemia‐reperfusion injury (HIRI) is a prevalent issue during liver resection and transplantation, with currently no cure or FDA‐approved therapy. A…”
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