Search Results - "Cai, Jian Piao"

Infection of bat and human intestinal organoids by SARS-CoV-2 by Zhou, Jie, Li, Cun, Liu, Xiaojuan, Chiu, Man Chun, Zhao, Xiaoyu, Wang, Dong, Wei, Yuxuan, Lee, Andrew, Zhang, Anna Jinxia, Chu, Hin, Cai, Jian-Piao, Yip, Cyril Chik-Yan, Chan, Ivy Hau-Yee, Wong, Kenneth Kak-Yuen, Tsang, Owen Tak-Yin, Chan, Kwok-Hung, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Chen, Honglin, Yuen, Kwok Yung

“…A novel coronavirus—severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)—emerged in humans in Wuhan, China, in December 2019 and has since disseminated…”
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A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster by Chan, Jasper Fuk-Woo, Yuan, Shuofeng, Kok, Kin-Hang, To, Kelvin Kai-Wang, Chu, Hin, Yang, Jin, Xing, Fanfan, Liu, Jieling, Yip, Cyril Chik-Yan, Poon, Rosana Wing-Shan, Tsoi, Hoi-Wah, Lo, Simon Kam-Fai, Chan, Kwok-Hung, Poon, Vincent Kwok-Man, Chan, Wan-Mui, Ip, Jonathan Daniel, Cai, Jian-Piao, Cheng, Vincent Chi-Chung, Chen, Honglin, Hui, Christopher Kim-Ming, Yuen, Kwok-Yung

“…An ongoing outbreak of pneumonia associated with a novel coronavirus was reported in Wuhan city, Hubei province, China. Affected patients were geographically…”
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Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron by Shuai, Huiping, Chan, Jasper Fuk-Woo, Hu, Bingjie, Chai, Yue, Yuen, Terrence Tsz-Tai, Yin, Feifei, Huang, Xiner, Yoon, Chaemin, Hu, Jing-Chu, Liu, Huan, Shi, Jialu, Liu, Yuanchen, Zhu, Tianrenzheng, Zhang, Jinjin, Hou, Yuxin, Wang, Yixin, Lu, Lu, Cai, Jian-Piao, Zhang, Anna Jinxia, Zhou, Jie, Yuan, Shuofeng, Brindley, Melinda A., Zhang, Bao-Zhong, Huang, Jian-Dong, To, Kelvin Kai-Wang, Yuen, Kwok-Yung, Chu, Hin

“…The Omicron (B.1.1.529) variant of SARS-CoV-2 emerged in November 2021 and is rapidly spreading among the human population 1 . Although recent reports reveal…”
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Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study by To, Kelvin Kai-Wang, Tsang, Owen Tak-Yin, Leung, Wai-Shing, Tam, Anthony Raymond, Wu, Tak-Chiu, Lung, David Christopher, Yip, Cyril Chik-Yan, Cai, Jian-Piao, Chan, Jacky Man-Chun, Chik, Thomas Shiu-Hong, Lau, Daphne Pui-Ling, Choi, Chris Yau-Chung, Chen, Lin-Lei, Chan, Wan-Mui, Chan, Kwok-Hung, Ip, Jonathan Daniel, Ng, Anthony Chin-Ki, Poon, Rosana Wing-Shan, Luo, Cui-Ting, Cheng, Vincent Chi-Chung, Chan, Jasper Fuk-Woo, Hung, Ivan Fan-Ngai, Chen, Zhiwei, Chen, Honglin, Yuen, Kwok-Yung

“…Coronavirus disease 2019 (COVID-19) causes severe community and nosocomial outbreaks. Comprehensive data for serial respiratory viral load and serum antibody…”
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Simulation of the Clinical and Pathological Manifestations of Coronavirus Disease 2019 (COVID-19) in a Golden Syrian Hamster Model: Implications for Disease Pathogenesis and Transmissibility by Chan, Jasper Fuk-Woo, Zhang, Anna Jinxia, Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Lee, Andrew Chak-Yiu, Chan, Wan-Mui, Fan, Zhimeng, Tsoi, Hoi-Wah, Wen, Lei, Liang, Ronghui, Cao, Jianli, Chen, Yanxia, Tang, Kaiming, Luo, Cuiting, Cai, Jian-Piao, Kok, Kin-Hang, Chu, Hin, Chan, Kwok-Hung, Sridhar, Siddharth, Chen, Zhiwei, Chen, Honglin, To, Kelvin Kai-Wang, Yuen, Kwok-Yung

“…Abstract Background A physiological small-animal model that resembles COVID-19 with low mortality is lacking. Methods Molecular docking on the binding between…”
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Attenuated Interferon and Proinflammatory Response in SARS-CoV-2–Infected Human Dendritic Cells Is Associated With Viral Antagonism of STAT1 Phosphorylation by Yang, Dong, Chu, Hin, Hou, Yuxin, Chai, Yue, Shuai, Huiping, Lee, Andrew Chak-Yiu, Zhang, Xi, Wang, Yixin, Hu, Bingjie, Huang, Xiner, Yuen, Terrence Tsz-Tai, Cai, Jian-Piao, Zhou, Jie, Yuan, Shuofeng, Zhang, Anna Jinxia, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung

“…Abstract Clinical manifestations of coronavirus disease 2019 (COVID-19) vary from asymptomatic virus shedding, nonspecific pharyngitis, to pneumonia with…”
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Surgical Mask Partition Reduces the Risk of Noncontact Transmission in a Golden Syrian Hamster Model for Coronavirus Disease 2019 (COVID-19) by Chan, Jasper Fuk-Woo, Yuan, Shuofeng, Zhang, Anna Jinxia, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Lee, Andrew Chak-Yiu, Fan, Zhimeng, Li, Can, Liang, Ronghui, Cao, Jianli, Tang, Kaiming, Luo, Cuiting, Cheng, Vincent Chi-Chung, Cai, Jian-Piao, Chu, Hin, Chan, Kwok-Hung, To, Kelvin Kai-Wang, Sridhar, Siddharth, Yuen, Kwok-Yung

“…Abstract Background Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is believed to be mostly…”
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Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters by Yuan, Shuofeng, Ye, Zi-Wei, Liang, Ronghui, Tang, Kaiming, Zhang, Anna Jinxia, Lu, Gang, Ong, Chon Phin, Man Poon, Vincent Kwok, Chan, Chris Chung-Sing, Mok, Bobo Wing-Yee, Qin, Zhenzhi, Xie, Yubin, Chu, Allen Wing-Ho, Chan, Wan-Mui, Ip, Jonathan Daniel, Sun, Haoran, Tsang, Jessica Oi-Ling, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Chan, Chris Chun-Yiu, Cai, Jian-Piao, Luo, Cuiting, Lu, Lu, Yip, Cyril Chik-Yan, Chu, Hin, To, Kelvin Kai-Wang, Chen, Honglin, Jin, Dong-Yan, Yuen, Kwok-Yung, Chan, Jasper Fuk-Woo

“…The in vivo pathogenicity, transmissibility, and fitness of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron (B.1.1.529) variant are…”
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Severe Acute Respiratory Syndrome Coronavirus 2 Infects and Damages the Mature and Immature Olfactory Sensory Neurons of Hamsters by Zhang, Anna Jinxia, Lee, Andrew Chak-Yiu, Chu, Hin, Chan, Jasper Fuk-Woo, Fan, Zhimeng, Li, Can, Liu, Feifei, Chen, Yanxia, Yuan, Shuofeng, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Cai, Jian-Piao, Wu, Kenneth Lap-Kei, Sridhar, Siddharth, Chan, Ying-Shing, Yuen, Kwok-Yung

“…Abstract Background Coronavirus disease 2019 (COVID-19) is primarily an acute respiratory tract infection. Distinctively, a substantial proportion of COVID-19…”
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Intravenous Injection of Coronavirus Disease 2019 (COVID-19) mRNA Vaccine Can Induce Acute Myopericarditis in Mouse Model by Li, Can, Chen, Yanxia, Zhao, Yan, Lung, David Christopher, Ye, Zhanhong, Song, Wenchen, Liu, Fei-Fei, Cai, Jian-Piao, Wong, Wan-Man, Yip, Cyril Chik-Yan, Chan, Jasper Fuk-Woo, To, Kelvin Kai-Wang, Sridhar, Siddharth, Hung, Ivan Fan-Ngai, Chu, Hin, Kok, Kin-Hang, Jin, Dong-Yan, Zhang, Anna Jinxia, Yuen, Kwok-Yung

“…Abstract Background Post-vaccination myopericarditis is reported after immunization with coronavirus disease 2019 (COVID-19) messenger RNA (mRNA) vaccines. The…”
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Host and viral determinants for efficient SARS-CoV-2 infection of the human lung by Chu, Hin, Hu, Bingjie, Huang, Xiner, Chai, Yue, Zhou, Dongyan, Wang, Yixin, Shuai, Huiping, Yang, Dong, Hou, Yuxin, Zhang, Xi, Yuen, Terrence Tsz-Tai, Cai, Jian-Piao, Zhang, Anna Jinxia, Zhou, Jie, Yuan, Shuofeng, To, Kelvin Kai-Wang, Chan, Ivy Hau-Yee, Sit, Ko-Yung, Foo, Dominic Chi-Chung, Wong, Ian Yu-Hong, Ng, Ada Tsui-Lin, Cheung, Tan To, Law, Simon Ying-Kit, Au, Wing-Kuk, Brindley, Melinda A., Chen, Zhiwei, Kok, Kin-Hang, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung

“…Understanding the factors that contribute to efficient SARS-CoV-2 infection of human cells may provide insights on SARS-CoV-2 transmissibility and…”
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Comparative tropism, replication kinetics, and cell damage profiling of SARS-CoV-2 and SARS-CoV with implications for clinical manifestations, transmissibility, and laboratory studies of COVID-19: an observational study by Chu, Hin, Chan, Jasper Fuk-Woo, Yuen, Terrence Tsz-Tai, Shuai, Huiping, Yuan, Shuofeng, Wang, Yixin, Hu, Bingjie, Yip, Cyril Chik-Yan, Tsang, Jessica Oi-Ling, Huang, Xiner, Chai, Yue, Yang, Dong, Hou, Yuxin, Chik, Kenn Ka-Heng, Zhang, Xi, Fung, Agnes Yim-Fong, Tsoi, Hoi-Wah, Cai, Jian-Piao, Chan, Wan-Mui, Ip, Jonathan Daniel, Chu, Allen Wing-Ho, Zhou, Jie, Lung, David Christopher, Kok, Kin-Hang, To, Kelvin Kai-Wang, Tsang, Owen Tak-Yin, Chan, Kwok-Hung, Yuen, Kwok-Yung

“…Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was reported from China in January, 2020. SARS-CoV-2 is efficiently transmitted from person to…”
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SARS-CoV-2 shedding and seroconversion among passengers quarantined after disembarking a cruise ship: a case series by Hung, Ivan Fan-Ngai, Cheng, Vincent Chi-Chung, Li, Xin, Tam, Anthony Raymond, Hung, Derek Ling-Lung, Chiu, Kelvin Hei-Yeung, Yip, Cyril Chik-Yan, Cai, Jian-Piao, Ho, Deborah Tip-Yin, Wong, Shuk-Ching, Leung, Sally Sau-Man, Chu, Man-Yee, Tang, Milky Oi-Yan, Chen, Jonathan Hon-Kwan, Poon, Rosana Wing-Shan, Fung, Agnes Yim-Fong, Zhang, Ricky Ruiqi, Yan, Erica Yuen-Wing, Chen, Lin-Lei, Choi, Charlotte Yee-Ki, Leung, Kit-Hang, Chung, Tom Wai-Hin, Lam, Sonia Hiu-Yin, Lam, Tina Poy-Wing, Chan, Jasper Fuk-Woo, Chan, Kwok-Hung, Wu, Tak-Chiu, Ho, Pak-Leung, Chan, Johnny Wai-Man, Lau, Chak-Sing, To, Kelvin Kai-Wang, Yuen, Kwok-Yung

“…A cruise ship is a closed-off environment that simulates the basic functioning of a city in terms of living conditions and interpersonal interactions. Thus,…”
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Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients by Zhang, Bao-zhong, Hu, Ye-fan, Chen, Lin-lei, Yau, Thomas, Tong, Yi-gang, Hu, Jing-chu, Cai, Jian-piao, Chan, Kwok-Hung, Dou, Ying, Deng, Jian, Wang, Xiao-lei, Hung, Ivan Fan-Ngai, To, Kelvin Kai-Wang, Yuen, Kwok Yung, Huang, Jian-Dong

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SPINK6 inhibits human airway serine proteases and restricts influenza virus activation by Wang, Dong, Li, Cun, Chiu, Man Chun, Yu, Yifei, Liu, Xiaojuan, Zhao, Xiaoyu, Huang, Jingjing, Cheng, Zhongshan, Yuan, Shuofeng, Poon, Vincent, Cai, Jian‐Piao, Chu, Hin, Chan, Jasper Fuk‐Woo, To, Kelvin Kai‐Wang, Yuen, Kwok Yung, Zhou, Jie

“…SPINK6 was identified in human skin as a cellular inhibitor of serine proteases of the KLK family. Airway serine proteases are required to cleave hemagglutinin…”
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Severe Acute Respiratory Syndrome (SARS) Coronavirus ORF8 Protein Is Acquired from SARS-Related Coronavirus from Greater Horseshoe Bats through Recombination by Lau, Susanna K P, Feng, Yun, Chen, Honglin, Luk, Hayes K H, Yang, Wei-Hong, Li, Kenneth S M, Zhang, Yu-Zhen, Huang, Yi, Song, Zhi-Zhong, Chow, Wang-Ngai, Fan, Rachel Y Y, Ahmed, Syed Shakeel, Yeung, Hazel C, Lam, Carol S F, Cai, Jian-Piao, Wong, Samson S Y, Chan, Jasper F W, Yuen, Kwok-Yung, Zhang, Hai-Lin, Woo, Patrick C Y

“…Despite the identification of horseshoe bats as the reservoir of severe acute respiratory syndrome (SARS)-related coronaviruses (SARSr-CoVs), the origin of…”
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Human Nasal Organoids Model SARS-CoV-2 Upper Respiratory Infection and Recapitulate the Differential Infectivity of Emerging Variants by Chiu, Man Chun, Li, Cun, Liu, Xiaojuan, Song, Wenjun, Wan, Zhixin, Yu, Yifei, Huang, Jingjing, Xiao, Ding, Chu, Hin, Cai, Jian-Piao, To, Kelvin Kai-Wang, Yuen, Kwok Yung, Zhou, Jie

“…The human upper respiratory tract, specifically the nasopharyngeal epithelium, is the entry portal and primary infection site of respiratory viruses…”
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SARS-CoV-2 infection induces inflammatory bone loss in golden Syrian hamsters by Qiao, Wei, Lau, Hui En, Xie, Huizhi, Poon, Vincent Kwok-Man, Chan, Chris Chung-Sing, Chu, Hin, Yuan, Shuofeng, Yuen, Terrence Tsz-Tai, Chik, Kenn Ka-Heng, Tsang, Jessica Oi-Ling, Chan, Chris Chun-Yiu, Cai, Jian-Piao, Luo, Cuiting, Yuen, Kwok-Yung, Cheung, Kenneth Man-Chee, Chan, Jasper Fuk-Woo, Yeung, Kelvin Wai-Kwok

“…Extrapulmonary complications of different organ systems have been increasingly recognized in patients with severe or chronic Coronavirus Disease 2019…”
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Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection by Intranasal or Intratesticular Route Induces Testicular Damage by Li, Can, Ye, Zhanhong, Zhang, Anna Jin Xia, Chan, Jasper Fuk Woo, Song, Wenchen, Liu, Feifei, Chen, Yanxia, Kwan, Mike Yat Wah, Lee, Andrew Chak Yiu, Zhao, Yan, Wong, Bosco Ho Yin, Yip, Cyril Chik Yan, Cai, Jian Piao, Lung, David Christopher, Sridhar, Siddharth, Jin, Dongyan, Chu, Hin, To, Kelvin Kai Wang, Yuen, Kwok Yung

“…Abstract Background The role of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the pathogenesis of testicular damage is uncertain. Methods We…”
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Accurate Diagnosis of COVID-19 by a Novel Immunogenic Secreted SARS-CoV-2 orf8 Protein by Wang, Xiaohui, Lam, Joy-Yan, Wong, Wan-Man, Yuen, Chun-Kit, Cai, Jian-Piao, Au, Shannon Wing-Ngor, Chan, Jasper Fuk-Woo, To, Kelvin K W, Kok, Kin-Hang, Yuen, Kwok-Yung

“…An accurate diagnostic test for early severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is the key weapon to control the coronavirus…”
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