Search Results - "Cai, Guoxiang"

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  1. 1

    Predicting distant metastasis and chemotherapy benefit in locally advanced rectal cancer by Liu, Zhenyu, Meng, Xiaochun, Zhang, Hongmei, Li, Zhenhui, Liu, Jiangang, Sun, Kai, Meng, Yankai, Dai, Weixing, Xie, Peiyi, Ding, Yingying, Wang, Meiyun, Cai, Guoxiang, Tian, Jie

    Published in Nature communications (27-08-2020)
    “…Distant metastasis (DM) is the main cause of treatment failure in locally advanced rectal cancer. Adjuvant chemotherapy is usually used for distant control…”
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  2. 2

    Fusobacterium nucleatum promotes chemoresistance to 5-fluorouracil by upregulation of BIRC3 expression in colorectal cancer by Zhang, Sheng, Yang, Yongzhi, Weng, Wenhao, Guo, Bomin, Cai, Guoxiang, Ma, Yanlei, Cai, Sanjun

    “…Emerging evidence suggests a potential relationship between gut microbiota and the host response to chemotherapeutic drugs including 5-fluorouracil (5-Fu)…”
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  3. 3

    Primary tumors release ITGBL1-rich extracellular vesicles to promote distal metastatic tumor growth through fibroblast-niche formation by Ji, Qing, Zhou, Lihong, Sui, Hua, Yang, Liu, Wu, Xinnan, Song, Qing, Jia, Ru, Li, Ruixiao, Sun, Jian, Wang, Ziyuan, Liu, Ningning, Feng, Yuanyuan, Sun, Xiaoting, Cai, Gang, Feng, Yu, Cai, Jianfeng, Cao, Yihai, Cai, Guoxiang, Wang, Yan, Li, Qi

    Published in Nature communications (05-03-2020)
    “…Tumor metastasis is a hallmark of cancer. Metastatic cancer cells often reside in distal tissues and organs in their dormant state. Mechanisms underlying the…”
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  4. 4

    Structural segregation of gut microbiota between colorectal cancer patients and healthy volunteers by Wang, Tingting, Cai, Guoxiang, Qiu, Yunping, Fei, Na, Zhang, Menghui, Pang, Xiaoyan, Jia, Wei, Cai, Sanjun, Zhao, Liping

    Published in The ISME Journal (01-02-2012)
    “…Despite a long-suspected role in the development of human colorectal cancer (CRC), the composition of gut microbiota in CRC patients has not been adequately…”
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  5. 5

    Prognostic impact of programed cell death-1 (PD-1) and PD-ligand 1 (PD-L1) expression in cancer cells and tumor infiltrating lymphocytes in colorectal cancer by Li, Yaqi, Liang, Lei, Dai, Weixing, Cai, Guoxiang, Xu, Ye, Li, Xinxiang, Li, Qingguo, Cai, Sanjun

    Published in Molecular cancer (24-08-2016)
    “…Colorectal cancer (CRC) is 3rd most commonly diagnosed cancer in males and the second in females. PD-1/PD-L1 axis, as an immune checkpoint, is up-regulated in…”
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  6. 6

    MALAT1 regulates the transcriptional and translational levels of proto-oncogene RUNX2 in colorectal cancer metastasis by Ji, Qing, Cai, Guoxiang, Liu, Xuan, Zhang, Yi, Wang, Yan, Zhou, Lihong, Sui, Hua, Li, Qi

    Published in Cell death & disease (16-05-2019)
    “…Ectopic expression of lncRNA-MALAT1 has been discovered in recurrent colorectal cancer (CRC) and metastatic sites in postsurgical patients, however, its…”
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  7. 7

    A clinical-radiomics nomogram for the preoperative prediction of lymph node metastasis in colorectal cancer by Li, Menglei, Zhang, Jing, Dan, Yibo, Yao, Yefeng, Dai, Weixing, Cai, Guoxiang, Yang, Guang, Tong, Tong

    Published in Journal of translational medicine (30-01-2020)
    “…Accurate lymph node metastasis (LNM) prediction in colorectal cancer (CRC) patients is of great significance for treatment decision making and prognostic…”
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  8. 8

    Development of a novel combined nomogram model integrating deep learning-pathomics, radiomics and immunoscore to predict postoperative outcome of colorectal cancer lung metastasis patients by Wang, Renjie, Dai, Weixing, Gong, Jing, Huang, Mingzhu, Hu, Tingdan, Li, Hang, Lin, Kailin, Tan, Cong, Hu, Hong, Tong, Tong, Cai, Guoxiang

    Published in Journal of hematology and oncology (24-01-2022)
    “…Limited previous studies focused on the death and progression risk stratification of colorectal cancer (CRC) lung metastasis patients. The aim of this study is…”
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  9. 9

    MiR-27a-3p functions as an oncogene in gastric cancer by targeting BTG2 by Zhou, Lin, Liang, Xin, Zhang, Lingling, Yang, Liyan, Nagao, Norio, Wu, Hongkun, Liu, Chang, Lin, Shengchao, Cai, Guoxiang, Liu, Jianwen

    Published in Oncotarget (09-08-2016)
    “…microRNA-27a (miR-27a) is frequently dysregulated in human carcinoma, including gastric cancer. The B-cell translocation gene 2 (BTG2) has been implicated in…”
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  10. 10

    The Critical Role of Tumor Size in Predicting Prognosis for T1 Colon Cancer by Dai, Weixing, Mo, Shaobo, Xiang, Wenqiang, Han, Lingyu, Li, Qingguo, Wang, Renjie, Xu, Ye, Cai, Guoxiang

    Published in The oncologist (Dayton, Ohio) (01-03-2020)
    “…Background The role of horizontal growth index of tumor size in survival prediction is still underappreciated in colon cancer because of the identification of…”
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  11. 11

    Antisense lncRNA LDLRAD4-AS1 promotes metastasis by decreasing the expression of LDLRAD4 and predicts a poor prognosis in colorectal cancer by Mo, Shaobo, Zhang, Long, Dai, Weixing, Han, Lingyu, Wang, Renjie, Xiang, Wenqiang, Wang, Zhimin, Li, Qingguo, Yu, Jun, Yuan, Jihang, Cai, Sanjun, Cai, Guoxiang

    Published in Cell death & disease (28-02-2020)
    “…Long noncoding RNAs (lncRNAs) have been revealed to play critical roles in tumor initiation and progression. The antisense lncRNA LDLRAD4-AS1 is the longest…”
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  12. 12

    A Distinct Metabolic Signature of Human Colorectal Cancer with Prognostic Potential by YUNPING QIU, GUOXIANG CAI, WEITING GE, ZHANXIANG ZHOU, XU, Lisa X, WEIPING JIA, SHU ZHENG, YUN YEN, WEI JIA, BINGSEN ZHOU, DAN LI, AIHUA ZHAO, GUOXIANG XIE, HOUKAI LI, SANJUN CAI, DONG XIE, CHANGZHI HUANG

    Published in Clinical cancer research (15-04-2014)
    “…Metabolic phenotyping has provided important biomarker findings, which, unfortunately, are rarely replicated across different sample sets due to the variations…”
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  13. 13

    Nomogram to predict the risk and survival of synchronous bone metastasis in colorectal cancer: a population-based real-world analysis by Han, Lingyu, Dai, Weixing, Mo, Shaobo, Xiang, Wenqiang, Li, Qingguo, Xu, Ye, Wang, Renjie, Cai, Guoxiang

    “…Purpose Bone metastasis (BM) can obviously affect the quality of life of patients in colorectal cancer (CRC), and the whole management of patients with BM…”
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  14. 14

    Serum Metabolite Profiling of Human Colorectal Cancer Using GC−TOFMS and UPLC−QTOFMS by Qiu, Yunping, Cai, Guoxiang, Su, Mingming, Chen, Tianlu, Zheng, Xiaojiao, Xu, Ye, Ni, Yan, Zhao, Aihua, Xu, Lisa X, Cai, Sanjun, Jia, Wei

    Published in Journal of proteome research (01-10-2009)
    “…Colorectal carcinogenesis involves the overexpression of many immediate-early response genes associated with growth and inflammation, which significantly…”
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  15. 15

    The safety and effectiveness of carbon nanoparticles suspension in tracking lymph node metastases of colorectal cancer: a prospective randomized controlled trial by Wang, Renjie, Mo, Shaobo, Liu, Qi, Zhang, Wenming, Zhang, Zhaozhen, He, Yiping, Cai, Guoxiang, Li, Xinxiang

    Published in Japanese journal of clinical oncology (05-05-2020)
    “…This study was to evaluate the safety and effectiveness of carbon nanoparticles suspension in tracking lymph node metastases of colorectal cancer. Eligible…”
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  16. 16

    Better long-term survival in young patients with non-metastatic colorectal cancer after surgery, an analysis of 69,835 patients in SEER database by Li, Qingguo, Cai, Guoxiang, Li, Dawei, Wang, Yuwei, Zhuo, Changhua, Cai, Sanjun

    Published in PloS one (01-04-2014)
    “…To compare the long-term survival of colorectal cancer (CRC) in young patients with elderly ones. Using Surveillance, Epidemiology, and End Results (SEER)…”
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  17. 17

    Deep learning radiomics-based prediction of distant metastasis in patients with locally advanced rectal cancer after neoadjuvant chemoradiotherapy: A multicentre study by Liu, Xiangyu, Zhang, Dafu, Liu, Zhenyu, Li, Zhenhui, Xie, Peiyi, Sun, Kai, Wei, Wei, Dai, Weixing, Tang, Zhenchao, Ding, Yingying, Cai, Guoxiang, Tong, Tong, Meng, Xiaochun, Tian, Jie

    Published in EBioMedicine (01-07-2021)
    “…Accurate predictions of distant metastasis (DM) in locally advanced rectal cancer (LARC) patients receiving neoadjuvant chemoradiotherapy (nCRT) are helpful in…”
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  18. 18

    GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies by Dai, Weixing, Xu, Ye, Mo, Shaobo, Li, Qingguo, Yu, Jun, Wang, Renjie, Ma, Yanlei, Ni, Yan, Xiang, Wenqiang, Han, Lingyu, Zhang, Long, Cai, Sanjun, Qin, Jun, Chen, Wen-Lian, Jia, Wei, Cai, Guoxiang

    Published in Signal transduction and targeted therapy (02-09-2020)
    “…Cancer cells are usually characterized by hyperactive glucose metabolism, which can often lead to glucose scarcity; thus, alternative pathways to rewire cancer…”
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  19. 19

    A robust gene signature for the prediction of early relapse in stage I–III colon cancer by Dai, Weixing, Li, Yaqi, Mo, Shaobo, Feng, Yang, Zhang, Long, Xu, Ye, Li, Qingguo, Cai, Guoxiang

    Published in Molecular oncology (01-04-2018)
    “…Colon cancer patients experiencing early relapse consistently exhibited poor survival. The aim of our study was to develop an mRNA signature that can help to…”
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  20. 20

    Development and Validation of an Autophagy Score Signature for the Prediction of Post-operative Survival in Colorectal Cancer by Zhou, Zheng, Mo, Shaobo, Dai, Weixing, Ying, Zhen, Zhang, Long, Xiang, Wenqiang, Han, Lingyu, Wang, Zhimin, Li, Qingguo, Wang, Renjie, Cai, Guoxiang

    Published in Frontiers in oncology (09-09-2019)
    “…Background: Survival rates for Colorectal cancer (CRC) patients who experienced early relapse have usually been relatively low. Our study aims at developing an…”
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