Search Results - "Cai, Guang‐Yan"

Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis by Chen, Nan, Hao, Chuanming, Liu, Bi-Cheng, Lin, Hongli, Wang, Caili, Xing, Changying, Liang, Xinling, Jiang, Gengru, Liu, Zhengrong, Li, Xuemei, Zuo, Li, Luo, Laimin, Wang, Jianqin, Zhao, Ming-hui, Liu, Zhihong, Cai, Guang-Yan, Hao, Li, Leong, Robert, Wang, Chunrong, Liu, Cameron, Neff, Thomas, Szczech, Lynda, Yu, Kin-Hung P

“…This randomized, phase 3 trial compared the effectiveness of roxadustat, an oral hypoxia-inducible factor prolyl hydroxylase inhibitor, with epoetin alfa in…”
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Energy restriction in renal protection by Wang, Si-Yang, Cai, Guang-Yan, Chen, Xiang-Mei

“…Energy restriction (ER) has been widely studied as a novel intervention, and its ability to prolong life has been fully demonstrated. For example, ER can…”
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Ginsenoside Rb1 alleviates diabetic kidney podocyte injury by inhibiting aldose reductase activity by He, Jia-yi, Hong, Quan, Chen, Bi-xia, Cui, Shao-yuan, Liu, Ran, Cai, Guang-yan, Guo, Jiao, Chen, Xiang-mei

“…Panax notoginseng , a traditional Chinese medicine, exerts beneficial effect on diabetic kidney disease (DKD), but its mechanism is not well clarified. In this…”
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Clinical and pathological factors associated with progression of diabetic nephropathy by Liang, Shuang, Cai, Guang‐Yan, Chen, Xiang‐Mei

“…Summary at a Glance This article reviews the values and limitations of some factors in the development and progression of diabetic kidney disease. ABSTRACT As…”
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Single-cell RNA sequencing data suggest a role for angiotensin-converting enzyme 2 in kidney impairment in patients infected with 2019-novel coronavirus by Deng, Yi-Yao, Zheng, Ying, Cai, Guang-Yan, Chen, Xiang-Mei, Hong, Quan

“…[...]ACE2 was found to be expressed predominantly in tubular precursors of the kidney of the fetal case [Supplemental Figure 1, http://links.lww.com/CM9/A212]…”
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Identification of key genes and pathways in diabetic nephropathy by bioinformatics analysis by Geng, Xiao‐dong, Wang, Wei‐wei, Feng, Zhe, Liu, Ran, Cheng, Xiao‐long, Shen, Wan‐jun, Dong, Zhe‐yi, Cai, Guang‐yan, Chen, Xiang‐mei, Hong, Quan, Wu, Di

“…Aims/Introduction The aim of the present study was to identify candidate differentially expressed genes (DEGs) and pathways using bioinformatics analysis, and…”
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Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling by Liu, Jun, Huang, Kun, Cai, Guang-Yan, Chen, Xiang-Mei, Yang, Ju-Rong, Lin, Li-Rong, Yang, Jie, Huo, Ben-Gang, Zhan, Jun, He, Ya-Ni

“…Premature senescence is a key process in the progression of diabetic nephropathy (DN). In our study, we hypothesized that receptors for advanced glycation…”
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Impact of ER stress-regulated ATF4/p16 signaling on the premature senescence of renal tubular epithelial cells in diabetic nephropathy by Liu, Jun, Yang, Ju-Rong, Chen, Xiang-Mei, Cai, Guang-Yan, Lin, Li-Rong, He, Ya-Ni

“…Premature senescence is an important event during diabetic nephropathy (DN) progression. Here, we investigated the role of endoplasmic reticulum (ER)…”
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Selection of urinary sediment miRNAs as specific biomarkers of IgA nephropathy by Duan, Zhi-Yu, Cai, Guang-yan, Bu, Ru, Lu, Yang, Hou, Kai, Chen, Xiang-Mei

“…The miRNAs in urinary sediment are easy to obtain, which provides a new approach to searching for non-invasive biomarkers of IgA nephropathy (IgAN). Compared…”
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Incidence, risk factors and prognosis of acute kidney injury in patients treated with immune checkpoint inhibitors: a retrospective study by Ji, Ming-Su, Wu, Rilige, Feng, Zhe, Wang, Yuan-Da, Wang, Yong, Zhang, Li, Sun, Xue-Feng, Chen, Xiang-Mei, He, Kun-Lun, Cai, Guang-Yan

“…Immune checkpoint inhibitors (ICIs) change the prognosis of many cancer patients. With the increasing use of ICIs, immune-related adverse events are occurring,…”
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Urinary miR-16-5p can be used as a potential marker of endocapillary hypercellularity in IgA nephropathy by Zhang, Meng, Duan, Zhi-Yu, Zhang, Qiu-Yue, Xu, Xie-Guan-Xuan, Zhang, Yan, Wang, Peng, Duan, Shu-Wei, Wu, Jie, Chen, Xiang-Mei, Cai, Guang-Yan

“…The most prevalent primary glomerulonephritis and leading cause of end-stage renal disease worldwide is IgA nephropathy (IgAN). More and more studies are…”
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U6 can be used as a housekeeping gene for urinary sediment miRNA studies of IgA nephropathy by Duan, Zhi-Yu, Cai, Guang-Yan, Li, Ji-Jun, Bu, Ru, Wang, NanNan, Yin, Pei, Chen, Xiang-Mei

“…Recent studies have indicated that urinary sediment miRNAs not only are able to serve as non-invasive diagnostic biomarkers for IgA nephropathy (IgAN) but may…”
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Risk factors for mortality in elderly haemodialysis patients: a systematic review and meta-analysis by Song, Yu-Huan, Cai, Guang-Yan, Xiao, Yue-Fei, Chen, Xiang-Mei

“…Older haemodialysis patients accompany a high burden of functional impairment, limited life expectancy, and healthcare utilization. This meta-analysis aimed to…”
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Identification of Potential Gene and MicroRNA Biomarkers of Acute Kidney Injury by Wang, Si-Yang, Gao, Jie, Song, Yu-huan, Cai, Guang-Yan, Chen, Xiang-Mei

“…Acute kidney injury (AKI) is a disease that seriously endangers human health. At present, AKI lacks effective treatment methods, so it is particularly…”
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Urinary miR-185-5p is a biomarker of renal tubulointerstitial fibrosis in IgA nephropathy by Duan, Zhi-Yu, Bu, Ru, Liang, Shuang, Chen, Xi-Zhao, Zhang, Chun, Zhang, Qiu-Yue, Li, Ji-Jun, Chen, Xiang-Mei, Cai, Guang-Yan

“…For IgA nephropathy (IgAN), tubular atrophy/interstitial fibrosis is the most important prognostic pathological indicator in the mesangial and endocapillary…”
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Alleviation of senescence and epithelial-mesenchymal transition in aging kidney by short-term caloric restriction and caloric restriction mimetics via modulation of AMPK/mTOR signaling by Dong, Dan, Cai, Guang-Yan, Ning, Yi-Chun, Wang, Jing-Chao, Lv, Yang, Hong, Quan, Cui, Shao-Yuan, Fu, Bo, Guo, Ya-Nan, Chen, Xiang-Mei

“…Renal fibrosis contributes to declining renal function in the elderly. What is unclear however, is whether epithelial-mesenchymal transition (EMT) contributes…”
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Transient upregulation of EGR1 signaling enhances kidney repair by activating SOX9 + renal tubular cells by Chen, Jian-Wen, Huang, Meng-Jie, Chen, Xiao-Niao, Wu, Ling-Ling, Li, Qing-Gang, Hong, Quan, Wu, Jie, Li, Fei, Chen, Liang-Mei, Dong, Yu, Cai, Guang-Yan, Bai, Xue-Yuan, Li, Zongjin, Chen, Xiang-Mei

“…Background: Acute kidney injury (AKI) is associated with damage to the nephrons and tubular epithelial cells (TECs), which can lead to chronic kidney disease…”
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miRNAs in stem cell-derived extracellular vesicles for acute kidney injury treatment: comprehensive review of preclinical studies by Wang, Si-Yang, Hong, Quan, Zhang, Chao-Yang, Yang, Yuan-Jun, Cai, Guang-Yan, Chen, Xiang-Mei

“…Stem cell therapy has been applied in many fields. Basic and clinical studies on stem cell therapy for acute kidney injury (AKI) have been conducted. Stem…”
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Identifying parameters to distinguish non-diabetic renal diseases from diabetic nephropathy in patients with type 2 diabetes mellitus: a meta-analysis by Liang, Shuang, Zhang, Xue-Guang, Cai, Guang-Yan, Zhu, Han-Yu, Zhou, Jian-Hui, Wu, Jie, Chen, Pu, Lin, Shu-Peng, Qiu, Qiang, Chen, Xiang-Mei

“…Renal injuries in patients with diabetes include diabetic nephropathy (DN) and non-diabetic renal diseases (NDRD). The value of a clinical diagnosis of DN and…”
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Relationship between serum C3/C4 ratio and prognosis of immunoglobulin A nephropathy based on propensity score matching by Zhang, Yan, Duan, Shu-Wei, Chen, Pu, Yin, Zhong, Wang, Yong, Cai, Guang-Yan, Chen, Xiang-Mei

“…Aberrant activation of the complement system plays an important role in the pathogenesis and development of immunoglobulin A nephropathy (IgAN). The…”
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