Search Results - "Cai, Chuanxi"

Information sharing and deferral option in cybersecurity investment by Cai, Chuanxi, Zhao, Liurong

“…This study investigates the effect of information sharing and deferral option on a firm's information security investment strategies by considering strategic…”
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MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling by Sermersheim, Matthew, Kenney, Adam D., Lin, Pei-Hui, McMichael, Temet M., Cai, Chuanxi, Gumpper, Kristyn, Adesanya, T. M. Ayodele, Li, Haichang, Zhou, Xinyu, Park, Ki-Ho, Yount, Jacob S., Ma, Jianjie

“…TRIM family proteins play integral roles in the innate immune response to virus infection. MG53 (TRIM72) is essential for cell membrane repair and is believed…”
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MG53 nucleates assembly of cell membrane repair machinery by Cai, Chuanxi, Masumiya, Haruko, Weisleder, Noah, Matsuda, Noriyuki, Nishi, Miyuki, Hwang, Moonsun, Ko, Jae-Kyun, Lin, Peihui, Thornton, Angela, Zhao, Xiaoli, Pan, Zui, Komazaki, Shinji, Brotto, Marco, Takeshima, Hiroshi, Ma, Jianjie

“…A phosphatidylserine-binding protein, MG53, is shown to participate in membrane repair. MG53 recruits vesicles to the repair site in an oxidation dependent…”
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Membrane Repair Defects in Muscular Dystrophy Are Linked to Altered Interaction between MG53, Caveolin-3, and Dysferlin by Cai, Chuanxi, Weisleder, Noah, Ko, Jae-Kyun, Komazaki, Shinji, Sunada, Yoshihide, Nishi, Miyuki, Takeshima, Hiroshi, Ma, Jianjie

“…Defective membrane repair can contribute to the progression of muscular dystrophy. Although mutations in caveolin-3 (Cav3) and dysferlin are linked to muscular…”
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Current Progress in the Rejuvenation of Aging Stem/Progenitor Cells for Improving the Therapeutic Effectiveness of Myocardial Repair by Kaur, Gurleen, Cai, Chuanxi

“…Ischemic heart disease affects a majority of people, especially elderly patients. Recent studies have utilized autologous adult stem/progenitor cells as a…”
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Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy by Weisleder, Noah, Takizawa, Norio, Lin, Peihui, Wang, Xianhua, Cao, Chunmei, Zhang, Yan, Tan, Tao, Ferrante, Christopher, Zhu, Hua, Chen, Pin-Jung, Yan, Rosalie, Sterling, Matthew, Zhao, Xiaoli, Hwang, Moonsun, Takeshima, Miyuki, Cai, Chuanxi, Cheng, Heping, Takeshima, Hiroshi, Xiao, Rui-Ping, Ma, Jianjie

“…Mitsugumin 53 (MG53), a muscle-specific TRIM family protein, is an essential component of the cell membrane repair machinery. Here, we examined the…”
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Gasdermin D promotes influenza virus-induced mortality through neutrophil amplification of inflammation by Speaks, Samuel, McFadden, Matthew I., Zani, Ashley, Solstad, Abigail, Leumi, Steve, Roettger, Jack E., Kenney, Adam D., Bone, Hannah, Zhang, Lizhi, Denz, Parker J., Eddy, Adrian C., Amer, Amal O., Robinson, Richard T., Cai, Chuanxi, Ma, Jianjie, Hemann, Emily A., Forero, Adriana, Yount, Jacob S.

“…Influenza virus activates cellular inflammasome pathways, which can be both beneficial and detrimental to infection outcomes. Here, we investigate the function…”
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MG53 suppresses tumor growth via transcriptional inhibition of KIF11 in pancreatic cancer by Wang, Xiao-Liang, He, Xiangfei, Gao, Tong, Zhou, Xinyu, Cruz-Monserrate, Zobeida, Tsung, Allan, Ma, Jianjie, Cai, Chuanxi

“…•Pancreatic tumors grew more aggressively in MG53 knockout mice compared to wild type mice in animal models.•MG53 localizes to the nucleus of pancreatic cancer…”
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The Heme Oxygenase 1 Inducer (CoPP) Protects Human Cardiac Stem Cells against Apoptosis through Activation of the Extracellular Signal-regulated Kinase (ERK)/NRF2 Signaling Pathway and Cytokine Release by Cai, Chuanxi, Teng, Lei, Vu, Duc, He, Jia-Qiang, Guo, Yiru, Li, Qianghong, Tang, Xian-Liang, Rokosh, Gregg, Bhatnagar, Aruni, Bolli, Roberto

“…Intracoronary delivery of c-kit-positive human cardiac stem cells (hCSCs) is a promising approach to repair the infarcted heart, but it is severely limited by…”
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Mitsugumin 53 regulates extracellular Ca2+ entry and intracellular Ca2+ release via Orai1 and RyR1 in skeletal muscle by Ahn, Mi Kyoung, Lee, Keon Jin, Cai, Chuanxi, Huang, Mei, Cho, Chung-Hyun, Ma, Jianjie, Lee, Eun Hui

“…Mitsugumin 53 (MG53) participates in the membrane repair of various cells, and skeletal muscle is the major tissue that expresses MG53. Except for the…”
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MG53's non-physiologic interaction with insulin receptor: lack of effect on insulin-stimulated Akt phosphorylation in muscle, heart and liver tissues by Lee, Kyung Eun, Nishi, Miyuki, Kim, Jongsoo, Murayama, Takashi, Dawson, Zachary, Wang, Xiaoliang, Zhou, Xinyu, Tan, Tao, Cai, Chuanxi, Takeshima, Hiroshi, Park, Ki Ho

“…MG53's known function in facilitating tissue repair and anti-inflammation has broad applications to regenerative medicine. There is controversy regarding…”
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MG53 Regulates Membrane Budding and Exocytosis in Muscle Cells by Cai, Chuanxi, Masumiya, Haruko, Weisleder, Noah, Pan, Zui, Nishi, Miyuki, Komazaki, Shinji, Takeshima, Hiroshi, Ma, Jianjie

“…Membrane recycling and remodeling contribute to multiple cellular functions, including cell fusion events during myogenesis. We have identified a tripartite…”
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Overexpression of GREM1 Improves the Survival Capacity of Aged Cardiac Mesenchymal Progenitor Cells via Upregulation of the ERK/NRF2-Associated Antioxidant Signal Pathway by Kaur, Gurleen, Wang, Xiaoliang, Li, Xiuchun, Ong, Hannah, He, Xiangfei, Cai, Chuanxi

“…Ischemic heart disease is the leading cause of mortality in the United States. Progenitor cell therapy can restore myocardial structure and function. However,…”
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Blocking Store-Operated Ca2+ Entry to Protect HL-1 Cardiomyocytes from Epirubicin-Induced Cardiotoxicity by Liu, Xian, Chang, Yan, Choi, Sangyong, Cai, Chuanxi, Zhang, Xiaoli, Pan, Zui

“…Epirubicin (EPI) is one of the most widely used anthracycline chemotherapy drugs, yet its cardiotoxicity severely limits its clinical application. Altered…”
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Cardiac effects and clinical applications of MG53 by Zhong, Weina, Benissan-Messan, Dathe Z, Ma, Jianjie, Cai, Chuanxi, Lee, Peter H U

“…Heart disease remains the leading cause of mortality globally, so further investigation is required to identify its underlying mechanisms and potential targets…”
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UCHL1 protects against ischemic heart injury via activating HIF-1α signal pathway by Geng, Bingchuan, Wang, Xiaoliang, Park, Ki Ho, Lee, Kyung Eun, Kim, Jongsoo, Chen, Peng, Zhou, Xinyu, Tan, Tao, Yang, Chunlin, Zou, Xunchang, Janssen, Paul M., Cao, Lei, Ye, Lei, Wang, Xuejun, Cai, Chuanxi, Zhu, Hua

“…Ubiquitin carboxyl-terminal esterase L1 (UCHL1) has been thought to be a neuron specific protein and shown to play critical roles in Parkinson's Disease and…”
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MG53 Mitigates Nitrogen Mustard-Induced Skin Injury by Li, Haichang, Li, Zhongguang, Li, Xiuchun, Cai, Chuanxi, Zhao, Serena Li, Merritt, Robert E, Zhou, Xinyu, Tan, Tao, Bergdall, Valerie, Ma, Jianjie

“…Sulfur mustard (SM) and nitrogen mustard (NM) are vesicant agents that cause skin injury and blistering through complicated cellular events, involving DNA…”
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Mitochondrial Membrane Potential Identifies a Subpopulation of Mesenchymal Progenitor Cells to Promote Angiogenesis and Myocardial Repair by Li, Xiuchun, Wang, Xiaoliang, He, Pan, Bennett, Edward, Haggard, Erin, Ma, Jianjie, Cai, Chuanxi

“…Identifying effective donor cells is one of obstacles that limits cell therapy for heart disease. In this study, we sorted a subpopulation of human mesenchymal…”
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Quantification of autophagy flux in isolated mouse skeletal muscle fibers with overexpression of fluorescent protein mCherry-EGFP-LC3 by Zhou, Xinyu, Cho, Ju Hwan, Yi, Jianxun, Choi, Kyounghan, Park, Ki Ho, Zhu, Hua, Cai, Chuanxi, Haggard, Erin, Zhou, Jingsong, Ko, Jae-Kyun, Ma, Jianjie

“…Evaluation of autophagy flux could be challenging for muscle fibers due to the baseline expression of mCherry-EGFP-LC3 along the Z-line. We established a…”
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Human Cardiac Progenitor Cells Enhance Exosome Release and Promote Angiogenesis Under Physoxia by Dougherty, Julie A, Patel, Nil, Kumar, Naresh, Rao, Shubha Gururaja, Angelos, Mark G, Singh, Harpreet, Cai, Chuanxi, Khan, Mahmood

“…Studies on cardiac progenitor cells (CPCs) and their derived exosomes therapeutic potential have demonstrated only modest improvements in cardiac function…”
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