Search Results - "Cahill, N"

Current Atlantic Meridional Overturning Circulation weakest in last millennium by Caesar, L., McCarthy, G. D., Thornalley, D. J. R., Cahill, N., Rahmstorf, S.

“…The Atlantic Meridional Overturning Circulation (AMOC)—one of Earth’s major ocean circulation systems—redistributes heat on our planet and has a major impact…”
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Prostaglandin D2 : A dominant mediator of aspirin-exacerbated respiratory disease by Cahill, Katherine N., MD, Bensko, Jillian C, Boyce, Joshua A., MD, Laidlaw, Tanya M., MD

“…Background Aspirin desensitization followed by high-dose aspirin therapy is routinely performed for patients with aspirin-exacerbated respiratory disease…”
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Allergic inflammatory memory in human respiratory epithelial progenitor cells by Ordovas-Montanes, Jose, Dwyer, Daniel F., Nyquist, Sarah K., Buchheit, Kathleen M., Vukovic, Marko, Deb, Chaarushena, Wadsworth, Marc H., Hughes, Travis K., Kazer, Samuel W., Yoshimoto, Eri, Cahill, Katherine N., Bhattacharyya, Neil, Katz, Howard R., Berger, Bonnie, Laidlaw, Tanya M., Boyce, Joshua A., Barrett, Nora A., Shalek, Alex K.

“…Barrier tissue dysfunction is a fundamental feature of chronic human inflammatory diseases 1 . Specialized subsets of epithelial cells—including secretory and…”
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Glucagon‐like peptide‐1 receptor agonist inhibits aeroallergen‐induced activation of ILC2 and neutrophilic airway inflammation in obese mice by Toki, Shinji, Newcomb, Dawn C., Printz, Richard L., Cahill, Katherine N., Boyd, Kelli L., Niswender, Kevin D., Peebles, R. Stokes

“…Background Obesity is a risk factor for the development of asthma. However, pharmacologic therapeutic strategies that specifically target obese asthmatics have…”
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Unique Effect of Aspirin Therapy on Biomarkers in Aspirin-exacerbated Respiratory Disease. A Prospective Trial by Cahill, Katherine N, Cui, Jing, Kothari, Parul, Murphy, Katherine, Raby, Benjamin A, Singer, Joseph, Israel, Elliot, Boyce, Joshua A, Laidlaw, Tanya M

“…Daily high-dose aspirin therapy benefits many patients with aspirin-exacerbated respiratory disease but provides no benefit for aspirin-tolerant patients with…”
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Aspirin-exacerbated respiratory disease: Mediators and mechanisms of a clinical disease by Cahill, Katherine N., MD, Boyce, Joshua A., MD

“…The clinical benefit of the 5-lypoxygenase inhibitor zileuton on basal respiratory symptoms, as well as its ability to shift the dose of aspirin needed to…”
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Reply to: Atlantic circulation change still uncertain by Caesar, L., McCarthy, G. D., Thornalley, D. J. R., Cahill, N., Rahmstorf, S.

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The role of prediction error and memory destabilization in extinction of cued-fear within the reconsolidation window by Cahill, Emma N, Wood, Melissa A, Everitt, Barry J, Milton, Amy L

“…Extinction of a cued-fear memory within the reconsolidation window has been proposed to prevent fear reacquisition by reconsolidation interference. This…”
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Thymic stromal lymphopoietin controls prostaglandin D2 generation in patients with aspirin-exacerbated respiratory disease by Buchheit, Kathleen M., MD, Cahill, Katherine N., MD, Katz, Howard R., PhD, Murphy, Katherine C., BA, Feng, Chunli, MD, Lee-Sarwar, Kathleen, MD, Lai, Juying, MD, Bhattacharyya, Neil, MD, Israel, Elliot, MD, Boyce, Joshua A., MD, Laidlaw, Tanya M., MD

“…Background Prostaglandin (PG) D2 is the dominant COX product of mast cells and is an effector of aspirin-induced respiratory reactions in patients with…”
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Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease by Cahill, Katherine N., Murphy, Katherine, Singer, Joseph, Israel, Elliot, Boyce, Joshua A., Laidlaw, Tanya M.

“…Plasma tryptase elevation during aspirin-induced respiratory reactions occurs in 50% of reactions despite CysLT 1 R antagonist prophylaxis and identifies lung…”
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Editorial: On the destabilization of maladaptive memory: updates and future perspectives by Radiske, Andressa, Cahill, Emma N, Milton, Amy L, Cammarota, Martín

“…Long-lasting consolidated memories can become destabilized when reactivated and, to endure, must undergo a protein synthesis-dependent restabilization in a…”
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Utility of Hypoglycemic Agents to Treat Asthma with Comorbid Obesity by Ge, Derek, Foer, Dinah, Cahill, Katherine N.

“…Adults with obesity may develop asthma that is ineffectively controlled by inhaled corticosteroids and long-acting beta-adrenoceptor agonists. Mechanistic and…”
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Current Knowledge and Management of Hypersensitivity to Aspirin and NSAIDs by Laidlaw, Tanya M., MD, Cahill, Katherine N., MD

“…Aspirin and nonsteroidal anti-inflammatory drugs (NSAIDs) are some of the most common culprits of drug-induced hypersensitivity reactions, and can lead to a…”
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On the way towards a ‘CLL prognostic index’: focus on TP53, BIRC3, SF3B1, NOTCH1 and MYD88 in a population-based cohort by Cortese, D, Sutton, L-A, Cahill, N, Smedby, K E, Geisler, C, Gunnarsson, R, Juliusson, G, Mansouri, L, Rosenquist, R

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Automated identification of an aspirin-exacerbated respiratory disease cohort by Cahill, Katherine N., MD, Johns, Christina B., BA, Cui, Jing, MD, PhD, Wickner, Paige, MD, MPH, Bates, David W., MD, MSc, Laidlaw, Tanya M., MD, Beeler, Patrick E., MD

“…Background Aspirin-exacerbated respiratory disease (AERD) is characterized by 3 clinical features: asthma, nasal polyposis, and respiratory reactions to…”
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450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments by Cahill, N, Bergh, A-C, Kanduri, M, Göransson-Kultima, H, Mansouri, L, Isaksson, A, Ryan, F, Smedby, K E, Juliusson, G, Sundström, C, Rosén, A, Rosenquist, R

“…In chronic lymphocytic leukemia (CLL), the microenvironment influences gene expression patterns; however, knowledge is limited regarding the extent to which…”
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NOTCH1 and SF3B1 mutations can be added to the hierarchical prognostic classification in chronic lymphocytic leukemia by Mansouri, L, Cahill, N, Gunnarsson, R, Smedby, K E, Tjönnfjord, E, Hjalgrim, H, Juliusson, G, Geisler, C, Rosenquist, R

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Distinct patterns of novel gene mutations in poor-prognostic stereotyped subsets of chronic lymphocytic leukemia: the case of SF3B1 and subset #2 by Strefford, J C, Sutton, L-A, Baliakas, P, Agathangelidis, A, Malčíková, J, Plevova, K, Scarfó, L, Davis, Z, Stalika, E, Cortese, D, Cahill, N, Pedersen, L B, di Celle, P F, Tzenou, T, Geisler, C, Panagiotidis, P, Langerak, A W, Chiorazzi, N, Pospisilova, S, Oscier, D, Davi, F, Belessi, C, Mansouri, L, Ghia, P, Stamatopoulos, K, Rosenquist, R

“…Recent studies have revealed recurrent mutations of the NOTCH1 , SF3B1 and BIRC3 genes in chronic lymphocytic leukemia (CLL), especially among aggressive,…”
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Contrasting records of sea-level change in the eastern and western North Atlantic during the last 300 years by Long, A.J., Barlow, N.L.M., Gehrels, W.R., Saher, M.H., Woodworth, P.L., Scaife, R.G., Brain, M.J., Cahill, N.

“…We present a new 300-year sea-level reconstruction from a salt marsh on the Isle of Wight (central English Channel, UK) that we compare to other salt-marsh and…”
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Pathogenesis of Aspirin-Induced Reactions in Aspirin-Exacerbated Respiratory Disease by Cahill, Katherine N., MD, Laidlaw, Tanya M., MD

“…The acute clinical symptoms that develop following the oral ingestion of aspirin, or any other inhibitor of cyclooxygenase-1, are well established in…”
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