Search Results - "Cahill, M R"

General practitioner views on the determinants of test ordering: a theory-based qualitative approach to the development of an intervention to improve immunoglobulin requests in primary care by Cadogan, S L, McHugh, S M, Bradley, C P, Browne, J P, Cahill, M R

“…Research suggests that variation in laboratory requesting patterns may indicate unnecessary test use. Requesting patterns for serum immunoglobulins vary…”
Get full text

Assessing Strategies to Reduce Inappropriate Laboratory Testing by Perry, C, Cahill, M R, Grieve, C, Reidy, N

Get full text

The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia by O'Connor, C, Lohan, F, Campos, J, Ohlsson, E, Salomè, M, Forde, C, Artschwager, R, Liskamp, R M, Cahill, M R, Kiely, P A, Porse, B, Keeshan, K

“…C/EBPα (p42 and p30 isoforms) is commonly dysregulated in cancer via the action of oncogenes, and specifically in acute myeloid leukaemia (AML) by mutation…”
Get full text

CyBorD-DARA in Newly Diagnosed Transplant-Eligible Multiple Myeloma: Results from the 16-BCNI-001/CTRIAL-IE 16-02 Study Show High Rates of MRD Negativity at End of Treatment by Swan, D., Henderson, R., McEllistrim, C., Naicker, S.D., Quinn, J., Cahill, M.R., Mykytiv, V., Lenihan, E., Mulvaney, E., Nolan, M., Parker, I., Natoni, A., Lynch, K., Ryan, A.E., Szegezdi, E., Krawczyk, J., Murphy, P., O'Dwyer, M.

“…The phase 1b 16-BCNI-001/CTRIAL-IE 16-02 CyBorD-DARA trial investigated the combination of Daratumumab with cyclophosphamide, bortezomib and dexamethasone in…”
Get full text

Platelets circulate in an activated state in inflammatory bowel disease by Collins, C E, Cahill, M R, Newland, A C, Rampton, D S

“…Platelets show proinflammatory as well as prothrombotic properties. Patients with inflammatory bowel disease are at increased risk of systemic thromboembolism,…”
Get more information

Protein A immunoadsorption in chronic refractory ITP reverses increased platelet activation but fails to achieve sustained clinical benefit by CAHILL, M. R, MACEY, M. G, CAVENAGH, J. D, NEWLAND, A. C

“…Adults with chronic relapsing ITP present a difficult therapeutic challenge. The ongoing antibody‐ mediated platelet destruction in this group might be…”
Get full text

CyBorD-DARA is potent initial induction for MM and enhances ADCP: initial results of the 16-BCNI-001/CTRIAL-IE 16-02 study by O'Dwyer, M., Henderson, R., Naicker, S.D., Cahill, M.R., Murphy, P., Mykytiv, V., Quinn, J., McEllistrim, C., Krawczyk, J., Walsh, J., Lenihan, E., Kenny, T., Hernando, A., Hirakata, G., Parker, I., Kinsella, E., Gannon, G., Natoni, A., Lynch, K., Ryan, A.E.

“…Daratumumab (DARA) has shown impressive activity in combination with other agents for the treatment of multiple myeloma (MM). We conducted a phase 1b study to…”
Get full text

Ionizing radiation exposure as a result of diagnostic imaging in patients with lymphoma by Crowley, M. P., O’Neill, S. B., Kevane, B., O’Neill, D. C., Eustace, J. A., Cahill, M. R., Bird, B., Maher, M. M., O’Regan, K., O’Shea, D.

“…Purpose Survival rates among patients with lymphoma continue to improve. Strategies aimed at reducing potential treatment-related toxicity are increasingly…”
Get full text

Haemophilia by Cahill, M. R., Colvin, B. T.

“…Although the nature of haemophilia has been understood for thousands of years, knowledge of its molecular genetics is recent. These X-linked bleeding disorders…”
Get full text

von Willebrand factor release and P-selectin expression is stimulated by thrombin and trypsin but not IL-1 in cultured human endothelial cells by Collins, P W, Macey, M G, Cahill, M R, Newland, A C

“…The stimulated release of von Willebrand factor (vWF) from endothelial cells by secretagogues such as thrombin is associated with the translocation of…”
Get more information

P‐selectin and glycoprotein 53 expression in myeloproliferative disorders by Cahill, Dr Mary R.

Get full text

new group of plant-derived naphthoquinone pesticides. [Erratum: Oct 1997, v. 51 (2), p. 223.] by Khambay, B.P.S, Batty, D, Beddie, D.G, Denholm, I, Cahill, M.R

“…A series of compounds with structures based on insecticidal/acaricidal naphthoquinones isolated from Calceolaria andina has been synthesised. A feature of the…”
Get full text

Fixation with formaldehyde induces expression of activation dependent platelet membrane glycoproteins, P selectin (CD62) and GP53 (CD63) by Cahill, M R, Macey, M G, Newland, A C

“…Platelet activation in vivo is important in the pathogenesis of thrombosis. Accurate measurement is difficult due to artefactual in vitro preparation related…”
Get more information

Is it refractory idiopathic thrombocytopenic purpura? by Cahill, M R, Newland, A C

Get more information

Phase I/II safety study of transfusion of prion-filtered red cell concentrates in transfusion-dependent patients by Cahill, M. R., Murphy, T., Khan, M., Fagan, J., Murphy, W. G.

“…Background and Objectives  Variant Creutzfeldt‐Jakob (vCJD) is a fatal transfusion transmissible prion infection. No test for vCJD in the donor population is…”
Get full text

Haemovigilance is associated with decreased use and improved appropriateness of blood transfusion by Cahill, M. R., Joyce, S., O'Brien, N., Casey, M.

Get full text

The issue of anti-D: an integrated seamless approach from recognition of need to bedside administration by Ryan, M J, Joyce, S, O'Brien, N, Lynch, E, Burke, G, Cahill, M R

“…The appropriate and timely administration of Anti-D immunoglobulin to Rhesus (D) negative women who have delivered Rhesus (D) positive babies is a vital part…”
Get full text

Platelet activation in coronary artery disease by Cahill, M R, Newland, A C

“…The role of platelets in coronary artery disease has become increasingly apparent in the last decade. Platelets are the main components of arterial thrombi,…”
Get more information

Clinical significance of platelet size in inflammatory bowel disease? by Collins, C E, Cahill, M R, Rampton, D S

Get more information

Treatment of acute myeloid leukaemia in pregnancy by Cavenagh, J D, Richardson, D S, Cahill, M R, Bernard, T, Kelsey, S M, Newland, A C

Get more information