Search Results - "Cagniard, Barbara"
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Age-dependent Motor Deficits and Dopaminergic Dysfunction in DJ-1 Null Mice
Published in The Journal of biological chemistry (03-06-2005)“…Mutations in the DJ-1 gene were recently identified in an autosomal recessive form of early-onset familial Parkinson disease. Structural biology, biochemistry,…”
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The endocannabinoid 2-arachidonoylglycerol negatively regulates habituation by suppressing excitatory recurrent network activity and reducing long-term potentiation in the dentate gyrus
Published in The Journal of neuroscience (20-02-2013)“…Endocannabinoids are known to mediate retrograde suppression of synaptic transmission, modulate synaptic plasticity, and influence learning and memory. The…”
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The Dopamine Transporter Expression Level Differentially Affects Responses to Cocaine and Amphetamine
Published in Journal of neurogenetics (01-06-2014)“…Abstract Although both cocaine and amphetamine mainly target the dopamine transporter (DAT) and cause psychomotor effects, they have very different mechanisms…”
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Task-specific enhancement of hippocampus-dependent learning in mice deficient in monoacylglycerol lipase, the major hydrolyzing enzyme of the endocannabinoid 2-arachidonoylglycerol
Published in Frontiers in behavioral neuroscience (02-06-2015)“…Growing evidence indicates that the endocannabinoid system is important for the acquisition and/or extinction of learning and memory. However, it is unclear…”
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Cocaine reward and locomotion stimulation in mice with reduced dopamine transporter expression
Published in BMC neuroscience (21-06-2007)“…The dopamine transporter (DAT) plays a critical role in regulating dopamine neurotransmission. Variations in DAT or changes in basal dopaminergic tone have…”
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Mice with Chronically Elevated Dopamine Exhibit Enhanced Motivation, but not Learning, for a Food Reward
Published in Neuropsychopharmacology (New York, N.Y.) (01-07-2006)“…Dopamine has been critically implicated in learning and motivation, although its precise role remains to be determined. In order to investigate the involvement…”
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Unregulated Cytosolic Dopamine Causes Neurodegeneration Associated with Oxidative Stress in Mice
Published in The Journal of neuroscience (09-01-2008)“…The role of dopamine as a vulnerability factor and a toxic agent in Parkinson's disease (PD) is still controversial, yet the presumed dopamine toxicity is…”
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Immunogenicity and Vaccine Shedding After 1 or 2 Doses of rVSVΔG-ZEBOV-GP Ebola Vaccine (ERVEBO®): Results From a Phase 2, Randomized, Placebo-controlled Trial in Children and Adults
Published in Clinical infectious diseases (10-04-2024)“…Abstract Background The rVSVΔG-ZEBOV-GP vaccine (ERVEBO®) is a single-dose, live-attenuated, recombinant vesicular stomatitis virus vaccine indicated for the…”
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Affective taste responses in the presence of reward- and aversion-conditioned stimuli and their relationship to psychomotor sensitization and place conditioning
Published in Behavioural brain research (01-01-2013)“…▸ Rewarding and aversive stimuli produce conditioned place preferences and aversions. ▸ Affective experience of tastants can be assessed by studying orofacial…”
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Hyperdopaminergic Mutant Mice Have Higher "Wanting" But Not "Liking" for Sweet Rewards
Published in The Journal of neuroscience (15-10-2003)“…What is the role of dopamine in natural rewards? A genetic mutant approach was taken to examine the consequences of elevated synaptic dopamine on (1)…”
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Dopamine Scales Performance in the Absence of New Learning
Published in Neuron (Cambridge, Mass.) (07-09-2006)“…Learning and motivation are integral in shaping an organism's adaptive behavior. The dopamine system has been implicated in both processes; however,…”
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Taste reactivity and its modulation by morphine and methamphetamine in C57BL/6 and DBA/2 mice
Published in Physiology & behavior (02-03-2009)“…Abstract C57BL/6J (B6) and DBA2/J (D2) mice differ markedly in voluntary consumption of tastants and responses to abused drugs. In particular, compared to D2…”
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Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries
Published in Trials (01-12-2021)“…Abstract Introduction The Ebola virus disease (EVD) outbreak in 2014–2016 in West Africa was the largest on record and provided an opportunity for large…”
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Endogenous nociceptin modulates diet preference independent of motivation and reward
Published in Physiology & behavior (20-04-2009)“…Abstract Previous studies show that the opioid peptide nociceptin stimulates food intake. Here, we studied nociceptin receptor knockout (NOP KO) mice in…”
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Impaired reward-related behaviors in mice lacking the endocannabinoid synthesizing enzyme diacylglycerol lipase alpha
Published in Neuroscience research (01-09-2011)Get full text
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Modulation of anxiety by μ-opioid receptors of the lateral septal region in mice
Published in Pharmacology, biochemistry and behavior (01-03-2006)“…Morphine and opiates are known to exert anxiolytic effects, probably by interacting with the GABAergic system. The lateral septum (LS), mainly constituted of…”
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A new model to evaluate affective states associated with reward-predicting cues in mice
Published in Neuroscience research (2007)Get full text
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Measurement of affective state during chronic nicotine treatment and withdrawal by affective taste reactivity in mice: The role of endocannabinoids
Published in Biochemical pharmacology (01-10-2009)“…Chronic nicotine treatment and spontaneous withdrawal did not influence taste reactions in mice, whereas AM251 differentially modulated taste reactions in…”
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A physiological role for endogenous nociceptin in the regulation of food intake and weight gain
Published in Neuroscience research (2007)Get full text
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Modulation by GABA transmission in the substantia nigra compacta and reticulata of locomotor activity in rats exposed to high pressure
Published in Neuroreport (11-05-1998)“…HELIUM pressure of > 20 bar causes neuroexcitatory changes referred to as the high pressure neurological syndrome. In rodents, symptoms include locomotor and…”
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