Search Results - "Caffrey, Brian"

Examining Nanoparticle Interactions on a Cellular Scale Using Correlative Light Electron Microscopy by Caffrey, Brian

“…One key area of nanomedicine research isthe mechanism of action of nanoparticles within the body, it’s biodistributionand pharmacokinetic properties. However,…”
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Cell-Cycle Proteins Control Production of Neutrophil Extracellular Traps by Amulic, Borko, Knackstedt, Sebastian Lorenz, Abu Abed, Ulrike, Deigendesch, Nikolaus, Harbort, Christopher J., Caffrey, Brian E., Brinkmann, Volker, Heppner, Frank L., Hinds, Philip W., Zychlinsky, Arturo

“…Neutrophils are essential for immune defense and can respond to infection by releasing chromatin in the form of neutrophil extracellular traps (NETs). Here we…”
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Nomadic lifestyle of Lactobacillus plantarum revealed by comparative genomics of 54 strains isolated from different habitats by Martino, Maria Elena, Bayjanov, Jumamurat R., Caffrey, Brian E., Wels, Michiel, Joncour, Pauline, Hughes, Sandrine, Gillet, Benjamin, Kleerebezem, Michiel, van Hijum, Sacha A.F.T., Leulier, François

“…Summary The ability of bacteria to adapt to diverse environmental conditions is well‐known. The process of bacterial adaptation to a niche has been linked to…”
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Liquid Phase Electron Microscopy of Bacterial Ultrastructure by Caffrey, Brian J, Pedrazo-Tardajos, Adrián, Liberti, Emanuela, Gaunt, Benjamin, Kim, Judy S, Kirkland, Angus I

“…Recent advances in liquid phase scanning transmission electron microscopy (LP-STEM) have enabled the study of dynamic biological processes at nanometer…”
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The Role of Ets2 Transcription Factor in the Induction of MicroRNA-155 (miR-155) by Lipopolysaccharide and Its Targeting by Interleukin-10 by Quinn, Susan R., Mangan, Niamh E., Caffrey, Brian E., Gantier, Michael P., Williams, Bryan R.G., Hertzog, Paul J., McCoy, Claire E., O'Neill, Luke A.J.

“…MicroRNA-155 (miR-155) is highly expressed in many cancers such as B cell lymphomas and myeloid leukemia and inflammatory disorders such as rheumatoid…”
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Semi-automated 3D segmentation of human skeletal muscle using Focused Ion Beam-Scanning Electron Microscopic images by Caffrey, Brian J., Maltsev, Alexander V., Gonzalez-Freire, Marta, Hartnell, Lisa M., Ferrucci, Luigi, Subramaniam, Sriram

“…[Display omitted] •High resolution 3D segmentation of human skeletal muscle mitochondria.•High-throughput, easy-to-use and versatile segmentation…”
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Breeding and wintering bird distributions in Britain and Ireland from citizen science bird atlases by Gillings, Simon, Balmer, Dawn E., Caffrey, Brian J., Downie, Iain S., Gibbons, David W., Lack, Peter C., Reid, James B., Sharrock, J. Tim R., Swann, Robert L., Fuller, Robert J., Fleishman, Erica

“…Motivation We undertook large citizen science surveys of bird distributions (atlases) in Britain and Ireland, aimed at quantifying breeding bird distributions…”
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The future distribution of wetland birds breeding in Europe validated against observed changes in distribution by Soultan, Alaaeldin, Pavón-Jordán, Diego, Bradter, Ute, Sandercock, Brett K, Hochachka, Wesley M, Johnston, Alison, Brommer, Jon, Gaget, Elie, Keller, Verena, Knaus, Peter, Aghababyan, Karen, Maxhuni, Qenan, Vintchevski, Alexandre, Nagy, Károly, Raudonikis, Liutauras, Balmer, Dawn, Noble, David, Leitão, Domingos, Øien, Ingar Jostein, Shimmings, Paul, Sultanov, Elchin, Caffrey, Brian, Boyla, Kerem, Radišić, Dimitrije, Lindström, Åke, Velevski, Metodija, Pladevall, Clara, Brotons, Lluís, Karel, Šťastný, Rajković, Draženko Z, Chodkiewicz, Tomasz, Wilk, Tomasz, Szép, Tibor, van Turnhout, Chris, Foppen, Ruud, Burfield, Ian, Vikstrøm, Thomas, Mazal, Vlatka Dumbović, Eaton, Mark, Vorisek, Petr, Lehikoinen, Aleksi, Herrando, Sergi, Kuzmenko, Tatiana, Bauer, Hans-Günther, Kalyakin, Mikhail V, Voltzit, Olga V, Sjeničić, Jovica, Pärt, Tomas

“…Wetland bird species have been declining in population size worldwide as climate warming and land-use change affect their suitable habitats. We used species…”
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The long noncoding RNA CHROME regulates cholesterol homeostasis in primates by Hennessy, Elizabeth J., van Solingen, Coen, Scacalossi, Kaitlyn R., Ouimet, Mireille, Afonso, Milessa S., Prins, Jurrien, Koelwyn, Graeme J., Sharma, Monika, Ramkhelawon, Bhama, Carpenter, Susan, Busch, Albert, Chernogubova, Ekaterina, Matic, Ljubica Perisic, Hedin, Ulf, Maegdefessel, Lars, Caffrey, Brian E., Hussein, Maryem A., Ricci, Emiliano P., Temel, Ryan E., Garabedian, Michael J., Berger, Jeffrey S., Vickers, Kasey C., Kanke, Matthew, Sethupathy, Praveen, Teupser, Daniel, Holdt, Lesca M., Moore, Kathryn J.

“…The human genome encodes thousands of long noncoding RNAs (lncRNAs), the majority of which are poorly conserved and uncharacterized. Here we identify a…”
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Screening for eukaryotic motifs in Legionella pneumophila reveals Smh1 as bacterial deacetylase of host histones by Herbel, Stefanie M., Moyon, Lambert, Christ, Marvin, Elsayed, Eslam M., Caffrey, Brian E., Malmsheimer, Silke, Grin, Iwan, Hoffmann, Kerstin, Surmann, Kristin, Blankenburg, Sascha, Jung, Anna Lena, Herkt, Christina E., Borsò, Marco, Bozdag, Beyza, Imhof, Axel, Becker, Anke, Wagner, Samuel, Bange, Gert, Völker, Uwe, Bertrams, Wilhelm, Marsico, Annalisa, Schmeck, Bernd

“…Legionella pneumophila (L.p.) is a bacterial pathogen which is a common causative agent of pneumonia. In humans, it infects alveolar macrophages and transfers…”
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Genome-wide Chromatin Profiling of Legionella pneumophila-Infected Human Macrophages Reveals Activation of the Probacterial Host Factor TNFAIP2 by Du Bois, IIona, Marsico, Annalisa, Bertrams, Wilhelm, Schweiger, Michal R., Caffrey, Brian E., Sittka-Stark, Alexandra, Eberhardt, Martin, Vera, Julio, Vingron, Martin, Schmeck, Bernd T.

“…Background. Legionella pneumophila is a causative agent of severe pneumonia. Infection leads to a broad host cell response, as evident, for example, on the…”
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A MicroRNA Network Controls Legionella pneumophila Replication in Human Macrophages via LGALS8 and MX1 by Herkt, Christina E, Caffrey, Brian E, Surmann, Kristin, Blankenburg, Sascha, Gesell Salazar, Manuela, Jung, Anna L, Herbel, Stefanie M, Hoffmann, Kerstin, Schulte, Leon N, Chen, Wei, Sittka-Stark, Alexandra, Völker, Uwe, Vingron, Martin, Marsico, Annalisa, Bertrams, Wilhelm, Schmeck, Bernd

“…is an important cause of pneumonia. It invades alveolar macrophages and manipulates the immune response by interfering with signaling pathways and gene…”
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PFAAT version 2.0: a tool for editing, annotating, and analyzing multiple sequence alignments by Caffrey, Daniel R, Dana, Paul H, Mathur, Vidhya, Ocano, Marco, Hong, Eun-Jong, Wang, Yaoyu E, Somaroo, Shyamal, Caffrey, Brian E, Potluri, Shobha, Huang, Enoch S

“…By virtue of their shared ancestry, homologous sequences are similar in their structure and function. Consequently, multiple sequence alignments are routinely…”
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Proteome-wide analysis of functional divergence in bacteria: exploring a host of ecological adaptations by Caffrey, Brian E, Williams, Tom A, Jiang, Xiaowei, Toft, Christina, Hokamp, Karsten, Fares, Mario A

“…Functional divergence is the process by which new genes and functions originate through the modification of existing ones. Both genetic and environmental…”
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Identification of 170 New Long Noncoding RNAs in Schistosoma mansoni by Guerra-Sá, Renata, Marsico, Annalisa, Couto, Flávia F. B., Mattos, Ana C. A., Coelho, Paulo M. Z., Jannotti-Passos, Liana Konovaloff, Mota, Ester A., Moares, Lauro A. G., Oliveira, Victor F., Caffrey, Brian E.

“…Long noncoding RNAs (lncRNAs) are transcripts generally longer than 200 nucleotides with no or poor protein coding potential, and most of their functions are…”
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Functional conservation of an ancestral Pellino protein in helminth species by Cluxton, Christopher D., Caffrey, Brian E., Kinsella, Gemma K., Moynagh, Paul N., Fares, Mario A., Fallon, Padraic G.

“…The immune system of H. sapiens has innate signaling pathways that arose in ancestral species. This is exemplified by the discovery of the Toll-like receptor…”
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Nuclear Factor κB2 p52 Protein Has a Role in Antiviral Immunity through IκB Kinase ϵ-dependent Induction of Sp1 Protein and Interleukin 15 by Doyle, Sarah L., Shirey, Kari Ann, McGettrick, Anne F., Kenny, Elaine F., Carpenter, Susan, Caffrey, Brian E., Gargan, Siobhan, Quinn, Susan R., Caamaño, Jorge H., Moynagh, Paul, Vogel, Stefanie N., O'Neill, Luke A.

“…In this study we describe a previously unreported function for NFκB2, an NFκB family transcription factor, in antiviral immunity. NFκB2 is induced in response…”
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Linker histone H1.2 and H1.4 affect the neutrophil lineage determination by Sollberger, Gabriel, Streeck, Robert, Apel, Falko, Caffrey, Brian Edward, Skoultchi, Arthur I, Zychlinsky, Arturo

“…Neutrophils are important innate immune cells that tackle invading pathogens with different effector mechanisms. They acquire this antimicrobial potential…”
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Phylogenomic inference of functional divergence by Williams, Tom A, Caffrey, Brian E, Jiang, Xiaowei, Toft, Christina, Fares, Mario A

“…Doc number: P4…”
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The long noncoding RNA CHROME regulates cholesterol homeostasis in primate by Hennessy, Elizabeth J, van Solingen, Coen, Scacalossi, Kaitlyn R, Ouimet, Mireille, Afonso, Milessa S, Prins, Jurrien, Koelwyn, Graeme J, Sharma, Monika, Ramkhelawon, Bhama, Carpenter, Susan, Busch, Albert, Chernogubova, Ekaterina, Matic, Ljubica Perisic, Hedin, Ulf, Maegdefessel, Lars, Caffrey, Brian E, Hussein, Maryem A, Ricci, Emiliano P, Temel, Ryan E, Garabedian, Michael J, Berger, Jeffrey S, Vickers, Kasey C, Kanke, Matthew, Sethupathy, Praveen, Teupser, Daniel, Holdt, Lesca M, Moore, Kathryn J

“…The human genome encodes thousands of long non-coding RNAs (lncRNAs), the majority of which are poorly conserved and uncharacterized. Here we identify a…”
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