Search Results - "Cado, Dragana"

NKG2D-Deficient Mice Are Defective in Tumor Surveillance in Models of Spontaneous Malignancy by Guerra, Nadia, Tan, Ying Xim, Joncker, Nathalie T., Choy, Augustine, Gallardo, Fermin, Xiong, Na, Knoblaugh, Susan, Cado, Dragana, Greenberg, Norman R., Raulet, David H.

“…Ligands for the NKG2D stimulatory receptor are frequently upregulated on tumor lines, rendering them sensitive to natural killer (NK) cells, but the role of…”
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Critical function for Naip5 in inflammasome activation by a conserved carboxy-terminal domain of flagellin by Vance, Russell E, Lightfield, Karla L, Persson, Jenny, Brubaker, Sky W, Dunipace, Eric A, Monack, Denise M, von Moltke, Jakob, Cado, Dragana, Dietrich, William F, Witte, Chelsea E, Henry, Thomas, Tsolis, Renée M, Sun, Yao-Hui

“…The molecular components of inflammasomes and what they sense are poorly defined. Vance and colleagues now show the carboxy-terminal 35 amino acids of…”
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Fas-associated death domain (FADD) is a negative regulator of T-cell receptor–mediated necroptosis by Osborn, Stephanie L., Diehl, Gretchen, Han, Seong-Ji, Xue, Ling, Kurd, Nadia, Hsieh, Kristina, Cado, Dragana, Robey, Ellen A., Winoto, Astar, Mak, Tak Wah

“…Cell death is an important mechanism to limit uncontrolled T-cell expansion during immune responses. Given the role of death-receptor adapter protein…”
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DDB2 Gene Disruption Leads to Skin Tumors and Resistance to Apoptosis after Exposure to Ultraviolet Light but Not a Chemical Carcinogen by Itoh, Toshiki, Cado, Dragana, Kamide, Ryoichi, Linn, Stuart, Croce, Carlo M.

“…Mutations in the human DDB2 gene give rise to xeroderma pigmentosum group E, a disease characterized by increased skin tumorigenesis in response to…”
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ERK5 MAPK Regulates Embryonic Angiogenesis and Acts as a Hypoxia-sensitive Repressor of Vascular Endothelial Growth Factor Expression by Sohn, Sue J, Sarvis, Brieana K, Cado, Dragana, Winoto, Astar

“…During angiogenesis, endothelial cells undergo proliferation, reorganization, and stabilization to establish a mature vascular network. This process is…”
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Comparative study of hematopoietic differentiation between human embryonic stem cell lines by Melichar, Heather, Li, Ou, Ross, Jenny, Haber, Hilary, Cado, Dragana, Nolla, Hector, Robey, Ellen A, Winoto, Astar

“…Directed differentiation of human embryonic stem cells (hESCs) into any desired cell type has been hailed as a therapeutic promise to cure many human diseases…”
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A Conserved Transcriptional Enhancer Regulates RAG Gene Expression in Developing B Cells by Hsu, Lih-Yun, Lauring, Josh, Liang, Hong-Erh, Greenbaum, Stephen, Cado, Dragana, Zhuang, Yuan, Schlissel, Mark S.

“…Although expression of the RAG1 and RAG2 genes is essential for lymphocyte development, the mechanisms responsible for the lymphoid- and developmental…”
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A Function of Fas-Associated Death Domain Protein in Cell Cycle Progression Localized to a Single Amino Acid at Its C-Terminal Region by Hua, Zi Chun, Sohn, Sue J, Kang, Chulho, Cado, Dragana, Winoto, Astar

“…FADD is an adaptor known to transmit apoptotic signals from members of the tumor necrosis factor receptor family. We show here that FADD has a domain…”
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Biallelic, ubiquitous transcription from the distal germline Igκ locus promoter during B cell development by Amin, Rupesh H, Cado, Dragana, Nolla, Hector, Huang, Dan, Shinton, Susan A, Zhou, Yan, Hardy, Richard R, Schlissel, Mark S

“…Allelic exclusion of Ig gene expression is necessary to limit the number of functional receptors to one per B cell. The mechanism underlying allelic exclusion…”
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The Orphan Steroid Receptor Nur77 Family Member Nor-1 Is Essential for Early Mouse Embryogenesis by DeYoung, R. Andrea, Baker, Julie C., Cado, Dragana, Winoto, Astar

“…Nur77 and its family members, Nor-1 and Nurr1, are orphan steroid receptors implicated in a wide variety of biological processes, including apoptosis and…”
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FADD-deficient T Cells Exhibit a Disaccord in Regulation of the Cell Cycle Machinery by Zhang, Jianke, Kabra, Nisha H., Cado, Dragana, Kang, Chulho, Winoto, Astar

“…FADD is an adapter protein that was originally isolated as a transducer of apoptotic signals for death domain-containing receptors. However, FADD-deficient…”
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A role for the orphan steroid receptor Nur77 in apoptosis accompanying antigen-induced negative selection by Cainan, Barbara J., Szychowski, Sharman, Ka-Ming Chan, Francis, Cado, Dragana, Winoto, Aster

“…The transcription factor Nur77, an orphan member of the nuclear hormone receptor superfamily, is highly expressed during T cell receptor-signaled apoptosis,…”
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Implications of CD94 Deficiency and Monoallelic NKG2A Expression for Natural Killer Cell Development and Repertoire Formation by Vance, Russell E., Jamieson, Amanda M., Cado, Dragana, Raulet, David H.

“…Natural killer (NK) cells are believed to achieve self-tolerance through the expression of self-MHC-specific inhibitory receptors, such as members of the Ly49…”
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Thymocyte Development is Normal in CTLA-4-Deficient Mice by Chambers, Cynthia A., Cado, Dragana, Truong, Thien, Allison, James P.

“…Recent studies indicate that CTLA-4 interaction with B7 ligands transduces an inhibitory signal to T lymphocytes. Mice homozygous for a null mutation in CTLA-4…”
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A New Element within the T-Cell Receptor α Locus Required for Tissue-Specific Locus Control Region Activity by Ortiz, Benjamin D., Cado, Dragana, Winoto, Astar

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules by Shastri, Nilabh, Hammer, Gianna Elena, Gonzalez, Federico, Champsaur, Marine, Cado, Dragana

“…Major histocompatibility complex (MHC) class I molecules present thousands of peptides to allow CD8(+) T cells to detect abnormal intracellular proteins. The…”
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Fas-mediated apoptosis and activation-induced T-cell proliferation are defective in mice lacking FADD/Mort1 by Winoto, Astar, Zhang, Jianke, Cado, Dragana, Chen, Ann, Kabra, Nisha H

“…Programmed cell death, or apoptosis, is important in homeostasis of the immune system: for example, non-functional or auto-reactive lymphocytes are eliminated…”
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Notch Activity Influences the αβ versus γδ T Cell Lineage Decision by Washburn, Tracy, Schweighoffer, Edina, Gridley, Thomas, Chang, David, Fowlkes, B.J, Cado, Dragana, Robey, Ellen

“…The choice between the αβ or γδ T cell fates is influenced by the production of functional, in-frame rearrangements of the TCR genes, but the mechanism that…”
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Chromosomal position of a VH gene segment determines its activation and inactivation as a substrate for V(D)J recombination by Bates, Jamie Geier, Cado, Dragana, Nolla, Hector, Schlissel, Mark S

“…Complete IgHC gene rearrangement occurs only in B cells in a stage-specific and ordered manner. We used gene targeting to reposition a distal V(H) gene segment…”
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Morphine-Induced Receptor Endocytosis in a Novel Knockin Mouse Reduces Tolerance and Dependence by Kim, Joseph A., Bartlett, Selena, He, Li, Nielsen, Carsten K., Chang, Amy M., Kharazia, Viktor, Waldhoer, Maria, Ou, Chrissi J., Taylor, Stacy, Ferwerda, Madeline, Cado, Dragana, Whistler, Jennifer L.

“…Opioid drugs, such as morphine, are among the most effective analgesics available. However, their utility for the treatment of chronic pain is limited by side…”
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