Search Results - "Cadman, E C"

The academic physician-investigator : a crisis not to be ignored by CADMAN, E. C

“…The academic physician-investigator faces many challenges. Obtaining funding to support research is the greatest impediment. The National Institutes of Health,…”
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Combined modality therapy for advanced Hodgkin's disease: 15-year follow-up data by Prosnitz, L R, Farber, L R, Kapp, D S, Scott, J, Bertino, J R, Fischer, J J, Cadman, E C

“…From 1969 through 1982, 184 patients with advanced Hodgkin's disease (HD) were treated with combined modality therapy (CMT) at Yale University. The data were…”
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An Internet-based law and medicine curriculum for residents by Balcezak, T, Lynch, P, Cadman, E C

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Acute effect of 5-fluorouracil on cytoplasmic and nuclear dihydrofolate reductase messenger RNA metabolism by Armstrong, R D, Lewis, M, Stern, S G, Cadman, E C

“…Studies were completed in C3-L5178Y cells, in which the DNA-coding region for dihydrofolate reductase messenger RNA (DHFR-mRNA) is amplified, to determine the…”
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Fluoropyrimidine-mediated changes in small nuclear RNA by Armstrong, R D, Takimoto, C H, Cadman, E C

“…Studies were completed to examine the effects of the antineoplastic agent 5-Fluorouridine (FUrd) on the metabolism of the small molecular weight nuclear RNA…”
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Detection by Polymerase Chain Reaction of Human Immunodeficiency Virus Type 1 Proviral DNA Sequences in Needles of Injecting Drug Users by Heimer, Robert, Myers, Samuel S., Cadman, Edwin C., Kaplan, Edward H.

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Acute nonlymphocytic leukemia: a delayed complication of Hodgkin's disease therapy: analysis of 109 cases by Cadman, E C, Capizzi, R L, Bertino, J R

“…The use of combined modality therapy (irradiation and combinations of drugs) in the treatment of Hodgkin's disease has produced a significant improvement in…”
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Precursor-dependent differences in the incorporation of fluorouracil in RNA by Takimoto, C H, Cadman, E C, Armstrong, R D

“…The distribution and level of 5-fluorouracil (FUra) incorporation into RNA were studied in S-180 murine tumor cells for two different fluoropyrimidine…”
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Inhibition of growth of leukemic cells by inhibitors of calmodulin: phenothiazines and melittin by HAIT, W. N, GRAIS, L, BENZ, C, CADMAN, E. C

“…Calmodulin, a ubiquitous calcium-binding protein, has recently been shown to play an important role in cellular proliferation. The calmodulin inhibitors…”
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Cytotoxicity of ketoconazole in malignant cell lines by ROCHLITZ, C. F, DAMON, L. E, RUSSI, B. M, CADMAN, E. C

“…The cytotoxic effects of ketoconazole, an antifungal agent known to have some activity against human prostate cancer, adrenal cancer, and male metastatic…”
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Combined total body electron beam irradiation and chemotherapy for mycosis fungoides by Braverman, I M, Yager, N B, Chen, M, Cadman, E C, Hait, W N, Maynard, T

“…Since 1979 a protocol of total body electron beam therapy (3,600 rads; 6 MeV), followed by six monthly cycles of chemotherapy (doxorubicin, 30 mg/M2 given…”
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The metabolic basis for combination chemotherapy by Damon, L E, Cadman, E C

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Sequence dependent synergistic cytotoxicity between etoposide and fluoropyrimidines by Damon, L E, Christensen, S, Rochlitz, C, Cadman, E C

“…The cytotoxic interactions between etoposide and two fluoropyrimidines (FP), 5-fluorouracil (FUra) and 5-fluoro-2'-deoxyuridine (FdUrd), were determined in…”
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Correlation between ribosomal RNA production and RNA-directed fluoropyrimidine cytotoxicity by Takimoto, C H, Tan, Y Y, Cadman, E C, Armstrong, R D

“…The relationship between cytotoxicity and fluoropyrimidine effects on the production of mature cytoplasmic 28S and 18S ribosomal RNA was studied in S-180 cells…”
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Bone involvement in Hodgkin's disease by Newcomer, L N, Silverstein, M B, Cadman, E C, Farber, L R, Bertino, J R, Prosnitz, L R

“…Eighteen patients with osseous involvement were identified from a series of 124 consecutive patients treated with combined-modality therapy with advanced-stage…”
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Enhanced 5-Fluorouracil Nucleotide Formation After Methotrexate Administration: Explanation for Drug Synergism by Cadman, Ed, Heimer, Robert, Davis, Lynn

“…Exposure of L1210 leukemia cells first to 0.1 to 100 micromolar methotrexate and then to 10 micromolar 5-fluorouracil produces a synergistic effect on the…”
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Pretreatment Hematocrit as an Independent Prognostic Variable in Hodgkin’s Disease by Jaffe, Howard S., Cadman, Edwin C., Farber, Lenard R., Bertino, Joseph R.

“…Pretreatment hematocrit in 117 advanced-stage Hodgkin's disease patients treated with a combined modality therapy program was evaluated as an independent…”
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Needle exchange decreases the prevalence of HIV-1 proviral DNA in returned syringes in New Haven, Connecticut by Heimer, R, Kaplan, E H, Khoshnood, K, Jariwala, B, Cadman, E C

“…To report on the deployment of the syringe tracking and testing system in the New Haven needle exchange program, which is the first federally funded evaluation…”
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The new physician-scientist: a guide for the 1990s by Cadman, E C

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Leptomeningeal mycosis fungoides by Lundberg, W B, Cadman, E C, Skeel, R T

“…Central nervous system involvement with mycosis fungoides complicated the clinical course of a patient at a time when his skin was clinically free of disease…”
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