Search Results - "Cadete, Virgilio Jj"
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Novel O-palmitolylated beta-E1 subunit of pyruvate dehydrogenase is phosphorylated during ischemia/reperfusion injury
Published in Proteome science (09-07-2010)“…During and following myocardial ischemia, glucose oxidation rates are low and fatty acids dominate as a source of oxidative metabolism. This metabolic…”
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Formation of mitochondrial‐derived vesicles is an active and physiologically relevant mitochondrial quality control process in the cardiac system
Published in The Journal of physiology (15-09-2016)“…Key points Mitochondrial‐derived vesicle (MDV) formation occurs under baseline conditions and is rapidly upregulated in response to stress‐inducing conditions…”
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Metabolic remodeling associated with subchronic doxorubicin cardiomyopathy
Published in Toxicology (Amsterdam) (11-04-2010)“…Abstract Doxorubicin (Adriamycin® ) is a potent and broad-spectrum antineoplastic agent, the clinical utility of which is restricted by a cumulative and…”
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Low Frequency Electromagnetic Field Conditioning Protects against I/R Injury and Contractile Dysfunction in the Isolated Rat Heart
Published in BioMed research international (01-01-2015)“…Low frequency electromagnetic field (LF-EMF) decreases the formation of reactive oxygen species, which are key mediators of ischemia/reperfusion (I/R) injury…”
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Proteomic analysis of right and left cardiac ventricles under aerobic conditions and after ischemia/reperfusion
Published in Proteomics (Weinheim) (01-08-2012)“…Ischemia/reperfusion (I/R) injury is a major consequence of a cardiovascular intervention. The study of changes of the left and right ventricle proteomes from…”
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Inhibition of MMP-2 Expression with siRNA Increases Baseline Cardiomyocyte Contractility and Protects against Simulated Ischemic Reperfusion Injury
Published in BioMed research international (01-01-2014)“…Matrix metalloproteinases (MMPs) significantly contribute to ischemia reperfusion (I/R) injury, namely, by the degradation of contractile proteins. However,…”
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Proliferative Versus Degenerative Paradigms in Pulmonary Arterial Hypertension
Published in Circulation research (14-04-2017)Get full text
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Synergistic protection of MLC 1 against cardiac ischemia/reperfusion-induced degradation: a novel therapeutic concept for the future
Published in Future medicinal chemistry (01-03-2013)“…Cardiovascular diseases are a major burden to society and a leading cause of morbidity and mortality in the developed world. Despite clinical and scientific…”
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