Search Results - "Caddell, J. Marc"

High-Affinity Inhibitors of Dihydrofolate Reductase:  Antimicrobial and Anticancer Activities of 7,8-Dialkyl-1,3-diaminopyrrolo[3,2-f]quinazolines with Small Molecular Size by Kuyper, Lee F, Baccanari, David P, Jones, Michael L, Hunter, Robert N, Tansik, Robert L, Joyner, Suzanne S, Boytos, Christine M, Rudolph, Sharon K, Knick, Vince, Wilson, H. Robert, Caddell, J. Marc, Friedman, Henry S, Comley, John C. W, Stables, Jeremy N

“…A series of 7,8-dialkylpyrrolo[3,2-f]quinazolines were prepared as inhibitors of dihydrofolate reductase (DHFR). On the basis of an apparent inverse…”
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Lewis acid assisted cyclization of arylcyanoguanidines to 2,4-diaminoquinazolines by Jones, Michael L., Kuyper, Lee F., Styles, Virgil L., Caddell, J. Marc

“…The mild preparation of N‐cyano‐N‐(1‐H‐indol‐5‐yl)guanidine and its cyclization to 1,3‐diamino‐7H‐pyrrolo[3,2‐f]quinazoline is described. Whereas previously…”
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