Search Results - "Cachot, Amélie"
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Optimized combinatorial pMHC class II multimer labeling for precision immune monitoring of tumor-specific CD4 T cells in patients
Published in Journal for immunotherapy of cancer (01-05-2020)“…BackgroundWith immunotherapy gaining increasing approval for treatment of different tumor types, scientists rely on cutting edge methods for the monitoring of…”
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510 Helping the killers: innovative cancer immunotherapy harnessing quasi-universal tumor antigen-specific CD4 T cells
Published in Journal for immunotherapy of cancer (01-11-2020)“…BackgroundWhile cancer immunotherapy has mainly focused on exploiting CD8 T cells given their role in the direct elimination of tumor cells, increasing…”
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545 Tumor-specific cytolytic CD4 T cells mediate protective immunity against human cancer
Published in Journal for immunotherapy of cancer (01-11-2020)“…BackgroundCD4 T cells have been implicated in cancer immunity for their helper functions. However, their direct cytotoxic potential remains elusive in cancer…”
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Tumor-specific cytolytic CD4 T cells mediate immunity against human cancer
Published in Science advances (01-02-2021)“…CD4 T cells have been implicated in cancer immunity for their helper functions. Moreover, their direct cytotoxic potential has been shown in some patients with…”
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High-throughput Screening of Human Tumor Antigen-specific CD4 T Cells, Including Neoantigen-reactive T Cells
Published in Clinical cancer research (15-07-2019)“…Characterization of tumor antigen-specific CD4 T-cell responses in healthy donors and malignant melanoma patients using an amplified T-cell library screening…”
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Effects of postmortem delays on protein composition and oxidation
Published in Brain research bulletin (01-03-2016)“…Graphical abstract…”
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Vaccination with long NY-ESO-1 79-108 peptide and CpG-B leads to robust activation of CD4 and CD8 T cell responses in stage III/IV melanoma patients, and a new HLA-DR7 epitope
Published in Journal for immunotherapy of cancer (04-11-2015)“…Although promising, the combination of long synthetic peptides and CpG-B oligodeoxynucleotides has not yet been tested as cancer vaccine. In this Phase I…”
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