Search Results - "Cabrera, Jésus A"
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Activation of the EGFR/p38/JNK pathway by mitochondrial-derived hydrogen peroxide contributes to oxygen-induced contraction of ductus arteriosus
Published in Journal of molecular medicine (Berlin, Germany) (01-09-2014)“…Oxygen-induced contraction of the ductus arteriosus (DA) involves a mitochondrial oxygen sensor, which signals pO 2 in the DA smooth muscle cell (DASMC) by…”
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The role of ion channels in hypoxic pulmonary vasoconstriction
Published in Advances in experimental medicine and biology (2010)“…Hypoxic pulmonary vasoconstriction (HPV) is an important mechanism by which localized flow of blood in small resistance pulmonary arteries is matched to…”
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Continued depression of maximal oxygen consumption and mitochondrial proteomic expression despite successful coronary artery bypass grafting in a swine model of hibernation
Published in The Journal of thoracic and cardiovascular surgery (2011)“…Objective Clinical studies indicate incomplete functional recovery of hibernating myocardium after coronary artery bypass grafting. We hypothesized that…”
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Pioglitazone increases PGC1-α signaling within chronically ischemic myocardium
Published in Basic research in cardiology (01-05-2016)“…The peroxisome proliferator-activated receptor (PPAR)-γ drug pioglitazone (PIO) has been shown to protect tissue against oxidant stress. In a swine model of…”
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Expression of uncoupling protein-2 remains increased within hibernating myocardium despite successful coronary artery bypass grafting at 4 wk post-revascularization
Published in The Journal of surgical research (01-01-2015)“…Abstract Background We have previously shown that mitochondrial uncoupling protein-2 (UCP-2) is increased in a swine model of hibernating myocardium (HM)…”
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Altered expression of mitochondrial electron transport chain proteins and improved myocardial energetic state during late ischemic preconditioning
Published in American journal of physiology. Heart and circulatory physiology (15-05-2012)“…Altered expression of mitochondrial electron transport proteins has been shown in early preconditioned myocardial tissue. We wished to determine whether these…”
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Reduced expression of mitochondrial electron transport chain proteins from hibernating hearts relative to ischemic preconditioned hearts in the second window of protection
Published in Journal of molecular and cellular cardiology (01-07-2013)“…Abstract Although protection against necrosis has been observed in both hibernating (HIB) and ischemic preconditioned hearts in the second window of protection…”
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Uncoupling protein-2 expression and effects on mitochondrial membrane potential and oxidant stress in heart tissue
Published in Translational research : the journal of laboratory and clinical medicine (01-05-2012)“…Myocardial uncoupling protein (UCP)-2 is increased with chronic peroxisome proliferator-activated receptor γ (PPARγ) stimulation, but the effect on membrane…”
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Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus
Published in Circulation (New York, N.Y.) (26-09-2006)“…At birth, the increase in oxygen causes contraction of the ductus arteriosus, thus diverting blood flow to the lungs. Although this contraction is modulated by…”
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Generation of oxidants by hypoxic human pulmonary and coronary smooth-muscle cells
Published in Chest (01-06-2008)“…Pulmonary vasoconstriction in response to hypoxia is unusual inasmuch as local exposure of nonpulmonary vasculature to hypoxia results in vasodilation. It has…”
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Reply to the Editor
Published in The Journal of thoracic and cardiovascular surgery (01-10-2011)Get full text
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Pioglitazone increases PGC1-[alpha] signaling within chronically ischemic myocardium
Published in Basic research in cardiology (01-05-2016)“…The peroxisome proliferator-activated receptor (PPAR)-γ drug pioglitazone (PIO) has been shown to protect tissue against oxidant stress. In a swine model of…”
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Abstract 9959: Chronic Administration of Pioglitazone and Pro-Oxidant Effects Within Chronic Hibernating Pig Hearts
Published in Circulation (New York, N.Y.) (26-11-2013)“…Abstract only Background: Glitazones have pleomorphic effects on myocardial metabolism. We hypothesized that the PPAR-gamma agent pioglitazone (PIO) would…”
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Abstract 9841: Expression of Mitochondrial Fusion Proteins is Increased in Hibernating Hearts Following Bypass Surgery
Published in Circulation (New York, N.Y.) (26-11-2013)“…Abstract only Background: Based on clinical studies, regional function within hibernating myocardium may not return to normal immediately following successful…”
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Prescripción de antibióticos en el Policlínico “Mártires de Calabazar”
Published in Revista Cubana de medicina general integral (01-06-2006)“…Se realizó un estudio observacional retrospectivo con el diseño de un estudio de utilización de medicamentos del tipo prescripción-indicación, en el…”
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Abstract 4180: Assessment of Hibernating Myocardium by Contrast Enhanced Computed Tomography in a Porcine Model
Published in Circulation (New York, N.Y.) (28-10-2008)“…Abstract only Contrast enhanced computed tomography (CT) is able to assess coronary stenosis and left ventricular function. Due to first pass effect it is able…”
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Abstract 2622: Serotonin And Endothelin Increase L-type Calcium Channel Current In Pulmonary Artery Smooth Muscle Cells, Unrelated To Changes In Membrane Potential
Published in Circulation (New York, N.Y.) (28-10-2008)“…Abstract only Serotonin (5-HT) and endothelin (ET-1) are both involved in the pathophysiology of idiopathic pulmonary arterial hypertension. In addition to the…”
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A novel mechanism for achieving transgene persistence in vivo after somatic gene transfer into hepatocytes
Published in The Journal of biological chemistry (05-06-1992)“…Infusion of hepatocyte-specific DNA-protein complexes into rats leads to transient recombinant gene expression in liver. The eventual deterioration of gene…”
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