Search Results - "Cabezon, Elena"

Towards an integrated model of bacterial conjugation by Cabezón, Elena, Ripoll-Rozada, Jorge, Peña, Alejandro, de la Cruz, Fernando, Arechaga, Ignacio

“…Bacterial conjugation is one of the main mechanisms for horizontal gene transfer. It constitutes a key element in the dissemination of antibiotic resistance…”
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Nanopore sensing reveals a preferential pathway for the co-translocational unfolding of a conjugative relaxase–DNA complex by Valenzuela-Gómez, Fernando, Arechaga, Ignacio, Rodríguez-Larrea, David, Cabezón, Elena

“…Abstract Bacterial conjugation is the main mechanism for the dissemination of antibiotic resistance genes. A single DNA strand of the conjugative plasmid is…”
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Spectrophotometric Assays to Quantify the Activity of T4SS ATPases by Cabezón, Elena, Arechaga, Ignacio

“…Biogenesis of T4SS apparatus and substrate transport require energy. Conjugative T4SS have three ATPases that enable DNA processing and transport of the…”
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Conjugation Inhibitors and Their Potential Use to Prevent Dissemination of Antibiotic Resistance Genes in Bacteria by Cabezón, Elena, de la Cruz, Fernando, Arechaga, Ignacio

“…Antibiotic resistance has become one of the most challenging problems in health care. Bacteria conjugation is one of the main mechanisms whereby bacteria…”
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Primary architecture and energy requirements of Type III and Type IV secretion systems by Cabezón, Elena, Valenzuela-Gómez, Fernando, Arechaga, Ignacio

“…Many pathogens use Type III and Type IV protein secretion systems to secrete virulence factors from the bacterial cytosol into host cells. These systems…”
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The FtsK-like motor TraB is a DNA-dependent ATPase that forms higher-order assemblies by Amado, Eric, Muth, Günther, Arechaga, Ignacio, Cabezón, Elena

“…TraB is an FtsK-like DNA translocase responsible for conjugative plasmid transfer in mycelial Streptomyces. Unlike other conjugative systems, which depend on a…”
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Drug Weaponry to Fight Against SARS-CoV-2 by Cabezón, Elena, Arechaga, Ignacio

“…The current outbreak of SARS-CoV-2 virus has caused a large increase in mortality and morbidity associated with respiratory diseases. Huge efforts are…”
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Monitoring Bacterial Conjugation by Optical Microscopy by Carranza, Gerardo, Menguiano, Tamara, Valenzuela-Gómez, Fernando, García-Cazorla, Yolanda, Cabezón, Elena, Arechaga, Ignacio

“…Bacterial conjugation is the main mechanism for horizontal gene transfer, conferring plasticity to the genome repertoire. This process is also the major…”
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Conjugation inhibitors compete with palmitic acid for binding to the conjugative traffic ATPase TrwD, providing a mechanism to inhibit bacterial conjugation by García-Cazorla, Yolanda, Getino, María, Sanabria-Ríos, David J., Carballeira, Néstor M., de la Cruz, Fernando, Arechaga, Ignacio, Cabezón, Elena

“…Bacterial conjugation is a key mechanism by which bacteria acquire antibiotic resistance. Therefore, conjugation inhibitors (COINs) are promising compounds in…”
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Functional Interactions of VirB11 Traffic ATPases with VirB4 and VirD4 Molecular Motors in Type IV Secretion Systems by Ripoll-Rozada, Jorge, Zunzunegui, Sandra, de la Cruz, Fernando, Arechaga, Ignacio, Cabezón, Elena

“…Pilus biogenesis and substrate transport by type IV secretion systems require energy, which is provided by three molecular motors localized at the base of the…”
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Type IV traffic ATPase TrwD as molecular target to inhibit bacterial conjugation by Ripoll‐Rozada, Jorge, García‐Cazorla, Yolanda, Getino, María, Machón, Cristina, Sanabria‐Ríos, David, de la Cruz, Fernando, Cabezón, Elena, Arechaga, Ignacio

“…Summary Bacterial conjugation is the main mechanism responsible for the dissemination of antibiotic resistance genes. Hence, the search for specific…”
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The Hexameric Structure of a Conjugative VirB4 Protein ATPase Provides New Insights for a Functional and Phylogenetic Relationship with DNA Translocases by Peña, Alejandro, Matilla, Inmaculada, Martín-Benito, Jaime, Valpuesta, José M., Carrascosa, José L., de la Cruz, Fernando, Cabezón, Elena, Arechaga, Ignacio

“…VirB4 proteins are ATPases essential for pilus biogenesis and protein transport in type IV secretion systems. These proteins contain a motor domain that shares…”
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Plasmid R1 Conjugative DNA Processing Is Regulated at the Coupling Protein Interface by MIHAJLOVIC, Sanja, LANG, Silvia, SUT, Marta V, STROHMAIER, Heimo, GRUBER, Christian J, KORAIMANN, Günther, CABEZON, Elena, MONCALIAN, Gabriel, DE LA CRUZ, Fernando, ZECHNER, Ellen L

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Fludarabine resistance mediated by aminoglycoside-3'-phosphotransferase-IIa and the structurally related eukaryotic cAMP-dependent protein kinase by Sánchez-Carrera, Dámaso, Bravo-Navas, Sara, Cabezón, Elena, Arechaga, Ignacio, Cabezas, Matilde, Yáñez, Lucrecia, Pipaón, Carlos

“…While working with G418-resistant stably transfected cells, we realized the neomycin resistance (NeoR) gene, which encodes the…”
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Substrate translocation involves specific lysine residues of the central channel of the conjugative coupling protein TrwB by Larrea, Delfina, de Paz, Héctor D., Matilla, Inmaculada, Guzmán-Herrador, Dolores L., Lasso, Gorka, de la Cruz, Fernando, Cabezón, Elena, Llosa, Matxalen

“…Conjugative transfer of plasmid R388 requires the coupling protein TrwB for protein and DNA transport, but their molecular role in transport has not been…”
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Regulation of the type IV secretion ATPase TrwD by magnesium: implications for catalytic mechanism of the secretion ATPase superfamily by Ripoll-Rozada, Jorge, Peña, Alejandro, Rivas, Susana, Moro, Fernando, de la Cruz, Fernando, Cabezón, Elena, Arechaga, Ignacio

“…TrwD, the VirB11 homologue in conjugative plasmid R388, is a member of the large secretion ATPase superfamily, which includes ATPases from bacterial type II…”
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Autoinhibitory Regulation of TrwK, an Essential VirB4 ATPase in Type IV Secretion Systems by Peña, Alejandro, Ripoll-Rozada, Jorge, Zunzunegui, Sandra, Cabezón, Elena, de la Cruz, Fernando, Arechaga, Ignacio

“…Type IV secretion systems (T4SS) mediate the transfer of DNA and protein substrates to target cells. TrwK, encoded by the conjugative plasmid R388, is a member…”
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Modulation of the Oligomerization State of the Bovine F1-ATPase Inhibitor Protein, IF1, by pH by Cabezon, Elena, Butler, P. Jonathan G., Runswick, Michael J., Walker, John E.

“…Bovine IF1, a basic protein of 84 amino acids, is involved in the regulation of the catalytic activity of the F1 domain of ATP synthase. At pH 6.5, but not at…”
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Homologous and Heterologous Inhibitory Effects of ATPase Inhibitor Proteins on F-ATPases by Cabezon, Elena, Butler, P Jonathan G, Runswick, Michael J, Carbajo, Rodrigo J, Walker, John E

“…In Saccharomyces cerevisiae , at least three proteins (IF 1 , STF 1 , and STF 2 ) appear to be involved in the regulation of ATP synthase. Both IF 1 and STF 1…”
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The Carboxyl Terminus of Protein TraD Adds Specificity and Efficiency to F-Plasmid Conjugative Transfer by Sastre, J. Ignacio, Cabezón, Elena, de la Cruz, Fernando

“…Article Usage Stats Services JB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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