Search Results - "Cabel, Luc"
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ERBB3 mutations in cancer: biological aspects, prevalence and therapeutics
Published in Oncogene (16-01-2020)“…HER3, a member of the EGFR family of receptor tyrosine kinases coded by the ERBB3 gene, plays an important role in cancer, despite its lack of intrinsic kinase…”
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2
Circulating tumor cells: clinical validity and utility
Published in International journal of clinical oncology (01-06-2017)“…Circulating tumor cells (CTCs) are rare tumor cells and have been investigated as diagnostic, prognostic and predictive biomarkers in many types of cancer…”
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3
Clinical utility of circulating tumor cells: an update
Published in Molecular oncology (01-06-2021)“…The prognostic role of circulating tumor cells (CTCs) has been clearly demonstrated in many types of cancer. However, their roles in diagnostic and treatment…”
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4
Clinical utility of circulating tumour cell-based monitoring of late-line chemotherapy for metastatic breast cancer: the randomised CirCe01 trial
Published in British journal of cancer (30-03-2021)“…Background CirCe01 trial aimed to assess the clinical utility of circulating tumour cell (CTC)-based monitoring in metastatic breast cancer (MBC) patients…”
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5
COVID-19 in breast cancer patients: a cohort at the Institut Curie hospitals in the Paris area
Published in Breast cancer research : BCR (28-05-2020)“…Cancer patients have been reported to be at higher risk of COVID-19 complications and deaths. We report the characteristics and outcome of patients diagnosed…”
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6
A single droplet digital PCR for ESR1 activating mutations detection in plasma
Published in Oncogene (02-04-2020)“…Activating mutations in the estrogen receptor 1 ( ESR1 ) gene confer resistance to aromatase inhibitors (AI), and may be targeted by selective estrogen…”
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7
Circulating tumor DNA as a dynamic biomarker of response to palbociclib and fulvestrant in metastatic breast cancer patients
Published in Breast cancer research : BCR (06-03-2021)“…Following the PALOMA-3 study results, the combination of palbociclib, a CDK4/6 inhibitor, with fulvestrant, a selective estrogen receptor degrader, has become…”
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8
Prognostic Impact of Residual HPV ctDNA Detection after Chemoradiotherapy for Anal Squamous Cell Carcinoma
Published in Clinical cancer research (15-11-2018)“…Chemoradiotherapy (CRT) is the current standard of care for patients diagnosed with locally advanced anal squamous cell carcinoma (ASCC), but some patients…”
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9
Dimethyl Fumarate Controls the NRF2/DJ-1 Axis in Cancer Cells: Therapeutic Applications
Published in Molecular cancer therapeutics (01-03-2017)“…The transcription factor NRF2 (NFE2L2), regulates important antioxidant and cytoprotective genes. It enhances cancer cell proliferation and promotes…”
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10
Circulating Tumor Cells in Early Breast Cancer
Published in JNCI cancer spectrum (01-06-2019)“…Circulating tumor cells (CTCs) are particularly rare in non-metastatic breast cancer, and the clinical validity of CTC detection in that clinical setting was…”
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11
Plasma thymidine kinase 1 activity and outcome of ER+ HER2- metastatic breast cancer patients treated with palbociclib and endocrine therapy
Published in Breast cancer research : BCR (14-09-2020)“…Previous cohort studies have reported plasma TK1 activity (pTKa) as a potential prognostic biomarker in estrogen receptor-positive (ER+) HER2-negative (HER2-)…”
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12
Circulating Tumor Cells and Circulating Tumor DNA Detection in Potentially Resectable Metastatic Colorectal Cancer: A Prospective Ancillary Study to the Unicancer Prodige-14 Trial
Published in Cells (Basel, Switzerland) (28-05-2019)“…The management of patients with colorectal cancer (CRC) and potentially resectable liver metastases (LM) requires quick assessment of mutational status and of…”
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13
Efficacy of taxanes rechallenge in first-line treatment of early metastatic relapse of patients with HER2-negative breast cancer previously treated with a (neo)adjuvant taxanes regimen: A multicentre retrospective observational study
Published in Breast (Edinburgh) (01-10-2022)“…Taxanes are one of the most effective chemotherapies (CT) in breast cancer (BC), but the efficacy of taxanes rechallenge in early metastatic relapse has been…”
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14
Characteristics and outcome of breast cancer-related microangiopathic haemolytic anaemia: a multicentre study
Published in Breast cancer research : BCR (19-01-2021)“…Cancer-related microangiopathic haemolytic anaemia (MAHA) is a rare but life-threatening paraneoplastic syndrome. Only single cases or small series have been…”
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15
Long-term complete remission with Ipilimumab in metastatic castrate-resistant prostate cancer: case report of two patients
Published in Journal for immunotherapy of cancer (18-04-2017)“…Prostate cancer is one of the most common cancers in men and the fourth leading cause of cancer mortality worldwide. Although major progress has been achieved…”
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16
Quantitative CT Extent of Lung Damage in COVID-19 Pneumonia Is an Independent Risk Factor for Inpatient Mortality in a Population of Cancer Patients: A Prospective Study
Published in Frontiers in oncology (03-09-2020)“…CT lung extent has emerged as a potential risk factor of COVID-19 pneumonia severity with mainly semiquantitative assessment, and outcome was not assessed in…”
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Prognostic value of CEC count in HER2-negative metastatic breast cancer patients treated with bevacizumab and chemotherapy: a prospective validation study (UCBG COMET)
Published in Angiogenesis (London) (01-05-2020)“…Background Proof of concept studies has reported that circulating endothelial cell (CEC) count may be associated with the outcome of HER2-negative metastatic…”
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Clinicopathological characteristics and prognosis of breast cancer patients with isolated central nervous system metastases in the multicentre ESME database
Published in Therapeutic advances in medical oncology (2022)“…Background: As a result of progress in diagnosis and treatment, there is a growing prevalence of metastatic breast cancer (MBC) with isolated CNS metastases…”
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Integrated molecular and pharmacological characterization of patient-derived xenografts from bladder and ureteral cancers identifies new potential therapies
Published in Frontiers in oncology (11-08-2022)“…Background Muscle-invasive bladder cancer (MIBC) and upper urinary tract urothelial carcinoma (UTUC) are molecularly heterogeneous. Despite chemotherapies,…”
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ESR1 Mutation Detection and Dynamics in Meningeal Carcinomatosis in Breast Cancer
Published in Journal of breast cancer (01-04-2020)“…mutation is frequently encountered in hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer (MBC),…”
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