Search Results - "Cabedo, Judit"

52727 Efficacy and Safety of Sarecycline in Chinese Patients with Acne Vulgaris: A Randomized, Multicenter, Double-Blind, Placebo-Controlled, Phase-3 Trial by Baykal, Tolga, Baykal, Tolga, Chen, Xue, Zhang, Jianzhong, Robles, Judit Cabedo, Kostov, Belchin, Gil, Esther Garcia

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4‑Amino-7,8-dihydro-1,6-naphthyridin-5(6H)‑ones as Inhaled Phosphodiesterase Type 4 (PDE4) Inhibitors: Structural Biology and Structure–Activity Relationships by Roberts, Richard S, Sevilla, Sara, Ferrer, Manel, Taltavull, Joan, Hernández, Begoña, Segarra, Victor, Gràcia, Jordi, Lehner, Martin D, Gavaldà, Amadeu, Andrés, Miriam, Cabedo, Judit, Vilella, Dolors, Eichhorn, Peter, Calama, Elena, Carcasona, Carla, Miralpeix, Montserrat

“…Rational design of a novel template of naphthyridinones rapidly led to PDE4 inhibitors with subnanomolar enzymatic potencies. X-ray crystallography confirmed…”
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Biphenyl Pyridazinone Derivatives as Inhaled PDE4 Inhibitors: Structural Biology and Structure–Activity Relationships by Gràcia, Jordi, Buil, Maria Antonia, Castro, Jordi, Eichhorn, Peter, Ferrer, Manel, Gavaldà, Amadeu, Hernández, Begoña, Segarra, Victor, Lehner, Martin D, Moreno, Imma, Pagès, Lluís, Roberts, Richard S, Serrat, Jordi, Sevilla, Sara, Taltavull, Joan, Andrés, Miriam, Cabedo, Judit, Vilella, Dolors, Calama, Elena, Carcasona, Carla, Miralpeix, Montserrat

“…Cyclic nucleotide cAMP is a ubiquitous secondary messenger involved in a plethora of cellular responses to biological agents involving activation of adenylyl…”
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Discovery of a Potent, Selective, and Orally Available PI3Kδ Inhibitor for the Treatment of Inflammatory Diseases by Erra, Montse, Taltavull, Joan, Gréco, Angelique, Bernal, Francisco Javier, Caturla, Juan Francisco, Gràcia, Jordi, Domínguez, María, Sabaté, Mar, Paris, Stéphane, Soria, Salomé, Hernández, Begoña, Armengol, Clara, Cabedo, Judit, Bravo, Mónica, Calama, Elena, Miralpeix, Montserrat, Lehner, Martin D

“…The delta isoform of the phosphatidylinositol 3-kinase (PI3Kδ) has been shown to have an essential role in specific immune cell functions and thus represents a…”
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Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas by Maestro, Miguel A., Boj, Sylvia F., Luco, Reini F., Pierreux, Christophe E., Cabedo, Judit, Servitja, Joan M., German, Michael S., Rousseau, Guy G., Lemaigre, Frédéric P., Ferrer, Jorge

“…During pancreatic organogenesis endocrine cells arise from non self-renewing progenitors that express Ngn3. The precursors that give rise to Ngn3+ cells are…”
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The S1P1 receptor antagonist W146 induces lymphopenia in mice. Demonstration that functional antagonism of S1P1 is the mechanism of lymphopenia evoked by fingolimod-like compounds. (140.15) by Godessart, Nuria, Mustafa, Sanam, Dolgachev, Vlad, Aulí, Mariona, Aguilar, Núria, Cabedo, Judit, Calbet, Marta, Domènech, Teresa, Domínguez, María, López, Rosa, Prats, Neus, Milligan, Graeme, Kunkel, Steven, Tarrasón, Gema

“…Abstract Agonists of sphingosine 1-phosphate receptor 1 (S1P1) are a novel class of immunosuppressants. S1P is the endogenous agonist of S1P1 and promotes…”
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