Search Results - "Cabeceiras, Peter"

Engineered CRISPR prime editors with compact, untethered reverse transcriptases by Grünewald, Julian, Miller, Bret R., Szalay, Regan N., Cabeceiras, Peter K., Woodilla, Christopher J., Holtz, Eliza Jane B., Petri, Karl, Joung, J. Keith

“…The CRISPR prime editor PE2 consists of a Streptococcus pyogenes Cas9 nickase (nSpCas9) fused at its C-terminus to a Moloney murine leukemia virus reverse…”
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The RAC1 P29S Hotspot Mutation in Melanoma Confers Resistance to Pharmacological Inhibition of RAF by WATSON, Ian R, LIREN LI, TSAI, Kenneth Y, DAVIES, Michael A, MILLS, Gordon B, CHIN, Lynda, CABECEIRAS, Peter K, MAHDAVI, Mozhdeh, GUTSCHNER, Tony, GENOVESE, Giannicola, GUOCAN WANG, ZHUANGNA FANG, TEPPER, James M, STEMKE-HALE, Katherine

“…Following mutations in BRAF and NRAS, the RAC1 c.85C>T single-nucleotide variant (SNV) encoding P29S amino acid change represents the next most frequently…”
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Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer by Fujimoto, Tara N, Colbert, Lauren E, Huang, Yanqing, Molkentine, Jessica M, Deorukhkar, Amit, Baseler, Laura, de la Cruz Bonilla, Marimar, Yu, Meifang, Lin, Daniel, Gupta, Sonal, Cabeceiras, Peter K, Kingsley, Charles V, Tailor, Ramesh C, Sawakuchi, Gabriel O, Koay, Eugene J, Piwnica-Worms, Helen, Maitra, Anirban, Taniguchi, Cullen M

“…When pancreatic cancer cannot be removed surgically, patients frequently experience morbidity and death from progression of their primary tumor. Radiation…”
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Abstract 659: Novel refinements for the autochthonous mouse model of cancer by Cabeceiras, Peter K., Joshi, Nikhil S., Jacks, Tyler

“…There are many levels of genetic regulation at play in autochthonous mouse models of cancer. For instance, mouse models can be programed to knockout tumor…”
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Inducible de novo expression of neoantigens in tumor cells and mice by Damo, Martina, Fitzgerald, Brittany, Lu, Yisi, Nader, Mursal, William, Ivana, Cheung, Julie F., Connolly, Kelli A., Foster, Gena G., Akama-Garren, Elliot, Lee, Da-Yae, Chang, Greg P., Gocheva, Vasilena, Schmidt, Leah M., Boileve, Alice, Wilson, Josephine H., Cui, Can, Monroy, Isabel, Gokare, Prashanth, Cabeceiras, Peter, Jacks, Tyler, Joshi, Nikhil S.

“…Inducible expression of neoantigens in mice would enable the study of endogenous antigen-specific naïve T cell responses in disease and infection, but has been…”
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Novel Extracellular Vesicle Modalities for Delivery of Genome Editor Ribonucleoprotein Complexes by Cabeceiras, Peter Keith

“…Genome editing reagents have undergone rapid advancements in terms of specificity and the types of edits that can be executed, but the hurdle of delivery in…”
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Inducible de novo expression of neoantigens in tumor cells and mice with NINJA by Damo, Martina, Fitzgerald, Brittany, Lu, Yisi, Nader, Mursal, William, Ivana, Cheung, Julie F., Connolly, Kelli A., Foster, Gena G., Akama-Garren, Elliot, Lee, Da-Yae, Chang, Greg P., Gocheva, Vasilena, Schmidt, Leah M., Boileve, Alice, Wilson, Josephine H., Cui, Can, Monroy, Isabel, Gokare, Prashanth, Cabeceiras, Peter, Jacks, Tyler, Joshi, Nikhil S.

“…Inducible expression of neoantigens in mice would enable the study of endogenous antigen-specific naïve T cell responses in disease and infection, but has been…”
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Abstract LB-214: The RAC1 P29S hotspot mutation in melanoma confers resistance to pharmacological inhibition of RAF by Watson, Ian R., Li, Liren, Cabeceiras, Peter K., Mahdavi, Mozhdeh, Fang, Zhuangna, Stemke-Hale, Katherine, Mills, Gordon B., Chin, Lynda

“…Following recurrent mutations in BRAF and NRAS, the RAC1 c.85C > T single nucleotide variant encoding P29S amino acid change represents the next most…”
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