Search Results - "Cabana, Valérie C"
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Quantitative Immunoblotting Analyses Reveal that the Abundance of Actin, Tubulin, Synaptophysin and EEA1 Proteins is Altered in the Brains of Aged Mice
Published in Neuroscience (21-08-2020)“…•Abundance of neuronal proteins, such as AMPA receptors, is not altered by normal aging.•Aged mouse brains show reduced abundance of actin and synaptophysin…”
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Functional interaction of ubiquitin ligase RNF167 with UBE2D1 and UBE2N promotes ubiquitination of AMPA receptor
Published in The FEBS journal (01-08-2021)“…Protein ubiquitination has been historically associated with protein degradation, but recent studies have demonstrated other cellular functions associated with…”
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From Drosophila to Human: Biological Function of E3 Ligase Godzilla and Its Role in Disease
Published in Cells (Basel, Switzerland) (23-01-2022)“…The ubiquitin-proteasome system is of fundamental importance in all fields of biology due to its impact on proteostasis and in regulating cellular processes…”
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AP-1 contributes to endosomal targeting of the ubiquitin ligase RNF13 via a secondary and novel non-canonical binding motif
Published in Journal of cell science (15-09-2024)“…Cellular trafficking between organelles is typically assured by short motifs that contact carrier proteins to transport them to their destination. The…”
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Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167
Published in International journal of molecular sciences (16-07-2022)“…Rab7 is a GTPase that controls late endosome and lysosome trafficking. Recent studies have demonstrated that Rab7 is ubiquitinated, a post-translational…”
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RNF13 Dileucine Motif Variants L311S and L312P Interfere with Endosomal Localization and AP-3 Complex Association
Published in Cells (Basel, Switzerland) (06-11-2021)“…Developmental and epileptic encephalopathies (DEE) are rare and serious neurological disorders characterized by severe epilepsy with refractory seizures and a…”
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