Search Results - "Caballero, Laura"

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    Unraveling the complexity of mitochondrial complex I assembly: A dynamic process by Sánchez-Caballero, Laura, Guerrero-Castillo, Sergio, Nijtmans, Leo

    Published in Biochimica et biophysica acta (01-07-2016)
    “…Mammalian complex I is composed of 44 different subunits and its assembly requires at least 13 specific assembly factors. Proper function of the mitochondrial…”
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    Journal Article
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    Cell Survival during Complete Nutrient Deprivation Depends on Lipid Droplet-fueled β-Oxidation of Fatty Acids by Cabodevilla, Ainara G., Sánchez-Caballero, Laura, Nintou, Eleni, Boiadjieva, Violeta G., Picatoste, Fernando, Gubern, Albert, Claro, Enrique

    Published in The Journal of biological chemistry (27-09-2013)
    “…Cells exposed to stress of different origins synthesize triacylglycerols and generate lipid droplets (LD), but the physiological relevance of this response is…”
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    Journal Article
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    Molecular mechanisms of β-cell dysfunction and death in monogenic forms of diabetes by Sanchez Caballero, Laura, Gorgogietas, Vyron, Arroyo, Maria Nicol, Igoillo-Esteve, Mariana

    “…Monogenetic forms of diabetes represent 1%-5% of all diabetes cases and are caused by mutations in a single gene. These mutations, that affect genes involved…”
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    Journal Article
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    Mortality prediction models after radical cystectomy for bladder tumour: A systematic review and critical appraisal by Sarrió‐Sanz, Pau, Martinez‐Cayuelas, Laura, Lumbreras, Blanca, Sánchez‐Caballero, Laura, Palazón‐Bru, Antonio, Gil‐Guillén, Vicente F., Gómez‐Pérez, Luis

    Published in European journal of clinical investigation (01-10-2022)
    “…Introduction To identify risk‐predictive models for bladder‐specific cancer mortality in patients undergoing radical cystectomy and assess their clinical…”
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    Activation of AMPA Receptors Mediates the Antidepressant Action of Deep Brain Stimulation of the Infralimbic Prefrontal Cortex by Jiménez-Sánchez, Laura, Castañé, Anna, Pérez-Caballero, Laura, Grifoll-Escoda, Marc, López-Gil, Xavier, Campa, Leticia, Galofré, Mireia, Berrocoso, Esther, Adell, Albert

    Published in Cerebral cortex (New York, N.Y. 1991) (01-06-2016)
    “…Although deep brain stimulation (DBS) has been used with success in treatment-resistant depression, little is known about its mechanism of action. We examined…”
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    Zwitter Ionization of Glycine at Outer Space Conditions due to Microhydration by Six Water Molecules by Schwaab, Gerhard, Pérez de Tudela, Ricardo, Mani, Devendra, Pal, Nitish, Roy, Tarun Kumar, Gabas, Fabio, Conte, Riccardo, Durán Caballero, Laura, Ceotto, Michele, Marx, Dominik, Havenith, Martina

    Published in Physical review letters (21-01-2022)
    “…We investigate glycine microsolvation with water molecules, mimicking astrophysical conditions, in our laboratory by embedding these clusters in helium…”
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    TMEM70 functions in the assembly of complexes I and V by Sánchez-Caballero, Laura, Elurbe, Dei M., Baertling, Fabian, Guerrero-Castillo, Sergio, van den Brand, Mariel, van Strien, Joeri, van Dam, Teunis J.P., Rodenburg, Richard, Brandt, Ulrich, Huynen, Martijn A., Nijtmans, Leo G.J.

    “…Protein complexes from the oxidative phosphorylation (OXPHOS) system are assembled with the help of proteins called assembly factors. We here delineate the…”
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    Mutation in mitochondrial complex IV subunit COX5A causes pulmonary arterial hypertension, lactic acidemia, and failure to thrive by Baertling, Fabian, Al‐Murshedi, Fathiya, Sánchez‐Caballero, Laura, Al‐Senaidi, Khalfan, Joshi, Niranjan P, Venselaar, Hanka, den Brand, Mariël AM, Nijtmans, Leo GJ, Rodenburg, Richard JT

    Published in Human mutation (01-06-2017)
    “…COX5A is a nuclear‐encoded subunit of mitochondrial respiratory chain complex IV (cytochrome c oxidase). We present patients with a homozygous pathogenic…”
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    Unveiling Zwitterionization of Glycine in the Microhydration Limit by Tripathi, Ravi, Durán Caballero, Laura, Pérez de Tudela, Ricardo, Hölzl, Christoph, Marx, Dominik

    Published in ACS omega (18-05-2021)
    “…Charge separation under solvation stress conditions is a fundamental process that comes in many forms in doped water clusters. Yet, the mechanism of…”
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    Mutations in mitochondrial complex I assembly factor NDUFAF3 cause Leigh syndrome by Baertling, Fabian, Sánchez-Caballero, Laura, Timal, Sharita, van den Brand, Mariël AM, Ngu, Lock Hock, Distelmaier, Felix, Rodenburg, Richard JT, Nijtmans, Leo GJ

    Published in Molecular genetics and metabolism (01-03-2017)
    “…NDUFAF3 is an assembly factor of mitochondrial respiratory chain complex I. Variants in NDUFAF3 have been identified as a cause of severe multisystem…”
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    A Heterozygous NDUFV1 Variant Aggravates Mitochondrial Complex I Deficiency in a Family with a Homoplasmic ND1 Variant by Baertling, Fabian, Sánchez-Caballero, Laura, van den Brand, Mariël A.M., Distelmaier, Felix, Janssen, Mirian C.H., Rodenburg, Richard J.T., Smeitink, Jan A.M., Nijtmans, Leo G.J.

    Published in The Journal of pediatrics (01-05-2018)
    “…We demonstrate that a heterozygous nuclear variant in the gene encoding mitochondrial complex I subunit NDUFV1 aggravates the cellular phenotype in the…”
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    De falacias y sofismas: una mirada cáustica sobre el imperio de la ley como axioma by Caballero Trenado, Laura

    Published in Díkaion (16-08-2022)
    “…Javier Vilaplana, especialista de extensa trayectoria en litigación, disecciona en este ensayo el concepto de nuevo cuño posverdad en el marco del proceso…”
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    Journal Article Book Review
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    Fluoxetine: a case history of its discovery and preclinical development by Perez-Caballero, Laura, Torres-Sanchez, Sonia, Bravo, Lidia, Mico, Juan Antonio, Berrocoso, Esther

    Published in Expert opinion on drug discovery (01-05-2014)
    “…Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of…”
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    Association of Cellular Adhesion Molecules and Oxidative Stress with Endothelial Function in Obstructive Sleep Apnea by Jurado-Gamez, Bernabe, Cabrera, Carlos Bujalance, Ballesteros, Laura Caballero, Hinojosa, Carmen Marin, Cabrera, Luis Muñoz, Perez-Jimenez, Francisco, Lopez-Miranda, Jose

    Published in Internal Medicine (01-01-2012)
    “…Objective To evaluate the impact of oxidative stress and cellular adhesion molecules on ischemic reactive hyperemia (IRH) in patients with OSA. Materials and…”
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    Ketamine promotes rapid and transient activation of AMPA receptor-mediated synaptic transmission in the dorsal raphe nucleus by Llamosas, Nerea, Perez-Caballero, Laura, Berrocoso, Esther, Bruzos-Cidon, Cristina, Ugedo, Luisa, Torrecilla, Maria

    “…Accumulating evidence indicates that the antidepressant effects of ketamine are, in part, mediated by an increase in the AMPA receptor-mediated…”
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