Search Results - "Caballero, J. Martin"

PARP-2 sustains erythropoiesis in mice by limiting replicative stress in erythroid progenitors by Farrés, J, Llacuna, L, Martin-Caballero, J, Martínez, C, Lozano, J J, Ampurdanés, C, López-Contreras, A J, Florensa, L, Navarro, J, Ottina, E, Dantzer, F, Schreiber, V, Villunger, A, Fernández-Capetillo, O, Yélamos, J

“…Erythropoiesis is a tightly regulated process in which multipotential hematopoietic stem cells produce mature red blood cells. Here we show that deletion of…”
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ZRF1 controls the retinoic acid pathway and regulates leukemogenic potential in acute myeloid leukemia by Demajo, S, Uribesalgo, I, Gutiérrez, A, Ballaré, C, Capdevila, S, Roth, M, Zuber, J, Martín-Caballero, J, Di Croce, L

“…Acute myeloid leukemia (AML) is frequently linked to epigenetic abnormalities and deregulation of gene transcription, which lead to aberrant cell proliferation…”
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ΔNp63α promotes adhesion of metastatic prostate cancer cells to the bone through regulation of CD82 by Di Giacomo, V, Tian, T V, Mas, A, Pecoraro, M, Batlle-Morera, L, Noya, L, Martín-Caballero, J, Ruberte, J, Keyes, W M

“…ΔNp63α is a critical mediator of epithelial development and stem cell function in a variety of tissues including the skin and breast, while overexpression of…”
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Long-Term Treatment with Alcaligenes faecalis A12C Improves Host Resistance to Pathogens in Septic Rats: Possible Contribution of Curdlan-Like Immune Trainer by Martel-Benítez, C J, Alayón-Afonso, R, Castillo, D Padilla, Chamizo-López, F J, García-Laorden, M Isabel, de Los Monteros Y Zayas, A Espinosa, Rivero-Vera, J C, Salgueiro, P Nogueira, Real, F, Bordes-Benítez, A, Quintana, A Martel, Peña, C Almeida, Cabrera, C Domínguez, González-Martín, J M, Caballero, J Martín, Beneyto, R Frías, Villar, Jesús, Martín-Barrasa, J L

“…Curdlan, a β-1,3/1,6-glucan found in Alcaligenes faecalis (A. faecalis) wall, activates innate and humoral immunity. The aim of this study is to evaluate…”
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Probiotic Properties of Alcaligenes faecalis Isolated from Argyrosomus regius in Experimental Peritonitis (Rat Model) by Gutiérrez-Falcón, A. I., Ramos-Nuez, A. M., de los Monteros y Zayas, A. Espinosa, Castillo, D. F. Padilla, García-Laorden, M. Isabel, Chamizo-López, F. J., Real Valcárcel, F., Campelo, F. Artilles, Benítez, A. Bordes, Salgueiro, P. Nogueira, Cabrera, C. Domínguez, Rivero-Vera, J. C., González-Martín, J. M., Caballero, J. Martín, Frías-Beneyto, R., Villar, Jesús, Martín-Barrasa, J. L.

“…A strain of Alcaligenes faecalis A12C ( A. faecalis A12C) isolated from Argyrosomus regius is a probiotic in fish. Previous experiments showed that A. faecalis…”
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Hoxa-10 and Cyclin D3 Overexpression in the Decidual Reaction in a Superovulation Protocol in Young Adult C57BL/6J Mice by Robles, T. Garcia, Fernández, R. A. García, García-Palencia, P., Arrabal, M. D., Maldonado, B. Sánchez, Pérez, M. A. Sánchez, Rollan, E., Caballero, J. Martin, Flores, J. M.

“…Following the performance of a superovulation protocol, multiple nodules were observed bilaterally in the uterine horns of 31 of 276 (11.2%) C57BL/6 J female…”
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Snail1 controls TGF-β responsiveness and differentiation of mesenchymal stem cells by Batlle, R, Alba-Castellón, L, Loubat-Casanovas, J, Armenteros, E, Francí, C, Stanisavljevic, J, Banderas, R, Martin-Caballero, J, Bonilla, F, Baulida, J, Casal, J I, Gridley, T, de Herreros, A García

“…The Snail1 transcriptional repressor plays a key role in triggering epithelial-to-mesenchymal transition. Although Snail1 is widely expressed in early…”
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Tumor susceptibility of p21(Waf1/Cip1)-deficient mice by Martín-Caballero, J, Flores, J M, García-Palencia, P, Serrano, M

“…The cell cycle regulator p21 mediates the ability of the tumor suppressor p53 to arrest cellular proliferation. We have examined the involvement of p21 in…”
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Tumorigenic activity of p21Waf1/Cip1 in thymic lymphoma by De la Cueva, E, García-Cao, I, Herranz, M, López, P, García-Palencia, P, Flores, J M, Serrano, M, Fernández-Piqueras, J, Martín-Caballero, J

“…The cell cycle inhibitor p21Waf1/Cip1 is among the most important mediators of the tumor suppressor p53. However, there is increasing evidence indicating that…”
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Loss of poly(ADP-ribose) polymerase-2 leads to rapid development of spontaneous T-cell lymphomas in p53-deficient mice by Nicolás, L, Martínez, C, Baró, C, Rodríguez, M, Baroja-Mazo, A, Sole, F, Flores, J M, Ampurdanés, C, Dantzer, F, Martin-Caballero, J, Aparicio, P, Yelamos, J

“…Poly(ADP-ribose) polymerase-2 (Parp-2) belongs to a family of enzymes that catalyse poly(ADP-ribosyl)ation of proteins. Parp-2 deficiency in mice (Parp-2 −/− )…”
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Disease states associated with telomerase deficiency appear earlier in mice with short telomeres by Herrera, Eloísa, Samper, Enrique, Martín-Caballero, Juan, Flores, Juana M., Lee, Han-Woong, Blasco, María A.

“…Mice deficient for the mouse telomerase RNA (mTR−/−) and lacking telomerase activity can only be bred for approximately six generations due to decreased male…”
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Increased epidermal tumors and increased skin wound healing in transgenic mice overexpressing the catalytic subunit of telomerase, mTERT, in basal keratinocytes by González-Suárez, Eva, Samper, Enrique, Ramírez, Angel, Flores, Juana M., Martín-Caballero, Juan, Jorcano, José L., Blasco, María A.

“…Telomerase transgenics are an important tool to assess the role of telomerase in cancer, as well as to evaluate the potential use of telomerase for gene…”
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Tumorigenic activity of p21 in thymic lymphoma

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Limited overlapping roles of P15(INK4b) and P18(INK4c) cell cycle inhibitors in proliferation and tumorigenesis by Latres, E, Malumbres, M, Sotillo, R, Martín, J, Ortega, S, Martín-Caballero, J, Flores, J M, Cordón-Cardo, C, Barbacid, M

“…Entry of quiescent cells into the cell cycle is driven by the cyclin D-dependent kinases Cdk4 and Cdk6. These kinases are negatively regulated by the INK4 cell…”
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Short telomeres result in organismal hypersensitivity to ionizing radiation in mammals by Goytisolo, F A, Samper, E, Martín-Caballero, J, Finnon, P, Herrera, E, Flores, J M, Bouffler, S D, Blasco, M A

“…Here we show a correlation between telomere length and organismal sensitivity to ionizing radiation (IR) in mammals. In particular, fifth generation (G5) mouse…”
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The cell cycle inhibitor p21 controls T-cell proliferation and sex-linked lupus development by Balomenos, Dimitrios, Martín-Caballero, Juan, García, Maria I, Prieto, Ignacio, Flores, Juana M, Serrano, Manuel, Martínez-A, Carlos

“…Here we show that the cell-cycle regulator p21 is involved in immune system function. T lymphocytes from p21-/- mice exhibit significant proliferative…”
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407 Nur77 is a Tumor Suppressor That Mediates P53 Antioncogenic Activities by Carneiro, C, Sanguinetti, D, Martinez, G, Pastoriza, M.C, Martin-Caballero, J, Cameselle-Teijeiro, J.M, Forteza, J, Dominguez, F, Seoane, J, Vidal, A

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Molecular bases of tropism in the PUR46 cluster of transmissible gastroenteritis coronaviruses by Ballesteros, M L, Sánchez, C M, Martin-Caballero, J, Enjuanes, L

“…Transmissible gastroenteritis coronavirus (TGEV) infects both, the enteric and the respiratory tract of swine. S protein, that is recognized by the cellular…”
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Distinct roles for PARP-1 and PARP-2 in c-Myc–driven B-cell lymphoma in mice by Galindo-Campos, Miguel A., Lutfi, Nura, Bonnin, Sarah, Martínez, Carlos, Velasco-Hernandez, Talia, García-Hernández, Violeta, Martín-Caballero, Juan, Ampurdanés, Coral, Gimeno, Ramón, Colomo, Lluis, Roué, Gaël, Guilbaud, Guillaume, Dantzer, Françoise, Navarro, Pilar, Murga, Matilde, Fernández-Capetillo, Oscar, Bigas, Anna, Menéndez, Pablo, Sale, Julian E., Yélamos, José

“…Dysregulation of the c-Myc oncogene occurs in a wide variety of hematologic malignancies, and its overexpression has been linked with aggressive tumor…”
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'Super p53' mice exhibit enhanced DNA damage response, are tumor resistant and age normally by García-Cao, Isabel, García-Cao, Marta, Martín-Caballero, Juan, Criado, Luis M., Klatt, Peter, Flores, Juana M., Weill, Jean-Claude, Blasco, María A., Serrano, Manuel

“…The tumor suppressor p53 is critical in preventing cancer due to its ability to trigger proliferation arrest and cell death upon the occurrence of a variety of…”
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