Search Results - "Caballero, Ana B"

Nanochaperone‐Based Strategies to Control Protein Aggregation Linked to Conformational Diseases by Caballero, Ana B., Gamez, Patrick

“…The generation of highly organized amyloid fibrils is associated with a wide range of conformational pathologies, including primarily neurodegenerative…”
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Leishmanicidal and Trypanocidal Activity of Metal Complexes with 1,2,4-Triazolo[1,5-a]pyrimidines: Insights on their Therapeutic Potential against Leishmaniasis and Chagas Disease by Salas, Juan M, Caballero, Ana B, Esteban-Parra, Ginés M, Méndez-Arriaga, José M

“…Since their first synthesis back in the early 20th century, 1,2,4-triazolo[1,5- a]pyrimidines have aroused increasing interest in very diverse areas ranging…”
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Highly Cytotoxic Ruthenium(II)-Arene Complexes from Bulky 1‑Pyrenylphosphane Ligands by Brissos, Rosa F, Clavero, Pau, Gallen, Albert, Grabulosa, Arnald, Barrios, Leoní A, Caballero, Ana B, Korrodi-Gregório, Luís, Pérez-Tomás, Ricardo, Muller, Guillermo, Soto-Cerrato, Vanessa, Gamez, Patrick

“…In the present study, the potential anti-neoplastic properties of a series of ruthenium half-sandwich complexes of formula…”
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Copper in Alzheimer’s disease: Implications in amyloid aggregation and neurotoxicity by Gamez, Patrick, Caballero, Ana B.

“…The relationship of copper dyshomeostasis with neurodegenerative diseases has become evident in the last years. Because of the major role that this metal ion…”
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Bacterial Inclusion Bodies for Anti-Amyloid Drug Discovery: Current and Future Screening Methods by Caballero, Ana B, Espargaró, Alba, Pont, Caterina, Busquets, Maria Antònia, Estelrich, Joan, Muñoz-Torrero, Diego, Gamez, Patrick, Sabate, Raimon

“…Amyloid aggregation is linked to an increasing number of human disorders from nonneurological pathologies such as type-2 diabetes to neurodegenerative ones…”
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Copper, dityrosine cross-links and amyloid-β aggregation by Vázquez, Guillem, Caballero, Ana B., Kokinda, Jakub, Hijano, Ana, Sabaté, Raimon, Gamez, Patrick

“…Copper is involved in Alzheimer’s disease (AD) where it appears to affect the aggregation of amyloid-β (Aβ) and to catalyze the production of reactive oxygen…”
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DNA-binding and in vitro cytotoxic activity of platinum(II) complexes of curcumin and caffeine by Censi, Valentina, Caballero, Ana B., Pérez-Hernández, Marta, Soto-Cerrato, Vanessa, Korrodi-Gregório, Luís, Pérez-Tomás, Ricardo, Dell'Anna, Maria Michela, Mastrorilli, Piero, Gamez, Patrick

“…Three Pt(II) complexes containing the natural ligands curcumin and caffeine, namely [Pt(curc)(PPh3)2]Cl (1), [PtCl(curc)(DMSO)] (2) (curc = deprotonated…”
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Peptidic Scaffolds To Reduce the Interaction of Cu(II) Ions with β‑Amyloid Protein by Caballero, Ana B, Iranzo, Olga, Hautier, Alexandre, Sabaté, Raimon, Gamez, Patrick

“…Competitive Cu­(II)-binding studies have been carried out between five decapeptides (both acyclic and cyclic), namely C-Asp, C-Asn, O-Asp, O DPro -Asp, and…”
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Evaluation of the metal-dependent cytotoxic behaviour of coordination compounds by Grau, Jordi, Renau, Cristina, Caballero, Ana B, Caubet, Amparo, Pockaj, Marta, Lorenzo, Julia, Gamez, Patrick

“…The [Cu(L)Cl2]2 and [Pt(L)Cl2] complexes were prepared from the simple Schiff-base ligand (E)-phenyl-N-((pyridin-2-yl)methylene)methanamine (L) and…”
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Evaluation of cobalt(III) complexes as potential hypoxia-responsive carriers of esculetin by Palmeira-Mello, Marcos V., Caballero, Ana B., Ribeiro, Juliana Martins, de Souza-Fagundes, Elaine Maria, Gamez, Patrick, Lanznaster, Mauricio

“…Differentiation between hypoxic and normoxic tissues have been exploited for the development of selective chemotherapeutic agents. In this context,…”
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Steric hindrance, ligand ejection and associated photocytotoxic properties of ruthenium(II) polypyridyl complexes by Herrera-Ramírez, Piedad, Berger, Sarah Alina, Josa, Dana, Aguilà, David, Caballero, Ana B., Fontova, Pere, Soto-Cerrato, Vanessa, Martínez, Manuel, Gamez, Patrick

“…Two ruthenium(II) polypyridyl complexes were prepared with the {Ru(phen) 2 } 2+ moiety and a third sterically non-hindering bidentate ligand, namely…”
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Dual Effect of Prussian Blue Nanoparticles on Aβ40 Aggregation: β‑Sheet Fibril Reduction and Copper Dyshomeostasis Regulation by Kowalczyk, Joanna, Grapsi, Ettore, Espargaró, Alba, Caballero, Ana B, Juárez-Jiménez, Jordi, Busquets, Maria A, Gamez, Patrick, Sabate, Raimon, Estelrich, Joan

“…Alzheimer’s disease (AD), affecting almost 50 million individuals worldwide, is currently the first cause of dementia. Despite the tremendous research efforts…”
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Thiosemicarbazone Derivatives as Inhibitors of Amyloid‑β Aggregation: Effect of Metal Coordination by Matesanz, Ana I, Caballero, Ana B, Lorenzo, Carmen, Espargaró, Alba, Sabaté, Raimon, Quiroga, Adoración G, Gamez, Patrick

“…Three thiosemicarbazone derivatives, namely 4-(dimethylamino)­benzaldehyde 4,4-dimethylthiosemicarbazone (HL 1 ), 4-(dimethylamino)­benzaldehyde…”
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Cobalt(III)-py2en systems as potential carriers of β-ketoester-based ligands by Palmeira-Mello, Marcos V., Caballero, Ana B., Herrera-Ramírez, Piedad, Costa, Analu R., Santana, Savyo S., Guedes, Guilherme P., Caubet, Amparo, Batista, Alzir Azevedo, Gamez, Patrick, Lanznaster, Mauricio

“…Two cobalt(III) complexes containing different β-ketoesters, namely [CoIII(L1)(py2en)](ClO4)2·H2O (1) and [CoIII(L2)(py2en)](ClO4)2 (2)…”
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Anti-toxoplasma activity and DNA-binding of copper(II) and zinc(II) coordination compounds with 5-nitroimidazole-based ligands by Navarro-Peñaloza, Rubí, Anacleto-Santos, Jhony, Rivera-Fernández, Norma, Sánchez-Bartez, Francisco, Gracia-Mora, Isabel, Caballero, Ana B., Gamez, Patrick, Barba-Behrens, Norah

“…Tetrahedral copper(II) and zinc(II) coordination compounds from 5-nitroimidazole derivatives, viz . 1-(2-chloroethyl)-2-methyl-5-nitroimidazole (cenz) and…”
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Drastic Effect of the Peptide Sequence on the Copper‐Binding Properties of Tripeptides and the Electrochemical Behaviour of Their Copper(II) Complexes by Mena, Silvia, Mirats, Andrea, Caballero, Ana B., Guirado, Gonzalo, Barrios, Leoní A., Teat, Simon J., Rodriguez‐Santiago, Luis, Sodupe, Mariona, Gamez, Patrick

“…The binding and electrochemical properties of the complexes CuII‐HAH, CuII‐HWH, CuII‐Ac‐HWH, CuII‐HHW, and CuII‐WHH have been studied by using NMR and UV/Vis…”
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Nanochaperone‐Based Strategies to Control Protein Aggregation Linked to Conformational Diseases by Caballero, Ana B., Gamez, Patrick

“…The generation of highly organized amyloid fibrils is associated with a wide range of conformational pathologies, including primarily neurodegenerative…”
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Bis(7-amino-1,2,4-triazolo[1,5-a]pyrimidin-4-ium) bis-(oxalato-κO,O)cuprate(II) dihydrate by Caballero, Ana B, Castillo, Oscar, Rodríguez-Diéguez, Antonio, Salas, Juan M

“…The structure of the title ionic compound, (C(5)H(6)N(5))(2)[Cu(C(2)O(4))(2)]·2H(2)O, consists of a centrosymmetric copper(II) oxalate dianion, two…”
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DNA-interacting properties of two analogous square-planar cis-chlorido complexes: copper versus palladium by Palmeira-Mello, Marcos V., Caballero, Ana B., Lopez-Espinar, Aida, Guedes, Guilherme P., Caubet, Amparo, de Souza, Alessandra M. Teles, Lanznaster, Mauricio, Gamez, Patrick

“…Two square-planar coordination compounds, namely [Cu(CPYA)Cl 2 ] ( 1 ) and [Pd(CPYA)Cl 2 ] ( 2 ), were prepared from the ligand 4-chloro- N…”
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Histidine-Rich Oligopeptides To Lessen Copper-Mediated Amyloid-β Toxicity by Caballero, Ana B., Terol-Ordaz, Laia, Espargaró, Alba, Vázquez, Guillem, Nicolás, Ernesto, Sabaté, Raimon, Gamez, Patrick

“…Brain copper imbalance plays an important role in amyloid‐β aggregation, tau hyperphosphorylation, and neurotoxicity observed in Alzheimer's disease (AD)…”
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