Search Results - "Cañizares, Francisco J"

Paclitaxel antitumor effect improvement in lung cancer and prevention of the painful neuropathy using large pegylated cationic liposomes by Jiménez-López, Julia, Bravo-Caparrós, Inmaculada, Cabeza, Laura, Nieto, Francisco R., Ortiz, Raúl, Perazzoli, Gloria, Fernández-Segura, Eduardo, Cañizares, Francisco J., Baeyens, José M., Melguizo, Consolación, Prados, José

“…[Display omitted] •Large and small liposomes (MLV and SUV) improve PTX efficacy in lung cancer cells.•Both, MLV and SUV, improve PTX antitumor activity in…”
Get full text

Grip strength in mice with joint inflammation: A rheumatology function test sensitive to pain and analgesia by Montilla-García, Ángeles, Tejada, Miguel Á., Perazzoli, Gloria, Entrena, José M., Portillo-Salido, Enrique, Fernández-Segura, Eduardo, Cañizares, Francisco J., Cobos, Enrique J.

“…Grip strength deficit is a measure of pain-induced functional disability in rheumatic disease. We tested whether this parameter and tactile allodynia, the…”
Get full text

Pharmacological differences in postoperative cutaneous sensitivity, pain at rest, and movement-induced pain in laparotomized mice by Santos-Caballero, Miriam, Hasoun, Makeya A., Huerta, Miguel Á., Ruiz-Cantero, M. Carmen, Tejada, Miguel Á., Robles-Funes, María, Fernández-Segura, Eduardo, Cañizares, Francisco J., González-Cano, Rafael, Cobos, Enrique J.

“…Postoperative pain management is challenging. We used mice with a transverse laparotomy to study tactile allodynia measured by the von Frey test, pain at rest…”
Get full text

Sigma-1 receptor agonism exacerbates immune-driven nociception: Role of TRPV1 + nociceptors by Ruiz-Cantero, M. Carmen, Huerta, Miguel Á., Tejada, Miguel Á., Santos-Caballero, Miriam, Fernández-Segura, Eduardo, Cañizares, Francisco J., Entrena, José M., Baeyens, José M., Cobos, Enrique J.

“…The analgesic effects of sigma-1 antagonists are undisputed, but the effects of sigma-1 agonists on pain are not well studied. Here, we used a mouse model to…”
Get full text

Improvement of the antioxidant and hypolipidaemic effects of cowpea flours (Vigna unguiculata) by fermentation: results of in vitro and in vivo experiments by Kapravelou, Garyfallia, Martínez, Rosario, Andrade, Ana M, López Chaves, Carlos, López-Jurado, María, Aranda, Pilar, Arrebola, Francisco, Cañizares, Francisco J, Galisteo, Milagros, Porres, Jesús M

“…BACKGROUND The antioxidant capacity and hypolipidaemic effects of Vigna unguiculata, as well as their potential improvement by different fermentation and…”
Get full text

Urinary bladder sigma-1 receptors: A new target for cystitis treatment by González-Cano, Rafael, Artacho-Cordón, Antonia, Romero, Lucía, Tejada, Miguel A., Nieto, Francisco R., Merlos, Manuel, Cañizares, Francisco J., Cendán, Cruz M., Fernández-Segura, Eduardo, Baeyens, José M.

“…[Display omitted] No adequate treatment is available for painful urinary bladder disorders such as interstitial cystitis/bladder pain syndrome, and the…”
Get full text

Genetic Inactivation and Pharmacological Blockade of Sigma-1 Receptors Prevent Paclitaxel-Induced Sensory-Nerve Mitochondrial Abnormalities and Neuropathic Pain in Mice by Nieto, Francisco R, Cendán, Cruz M, Cañizares, Francisco J, Cubero, María A, Vela, José M, Fernández-Segura, Eduardo, Baeyens, José M

“…Background: Paclitaxel, a widely-used antineoplastic drug, produces a painful peripheral neuropathy that in rodents is associated with peripheral-nerve…”
Get full text

Intracolonic Mustard Oil Induces Visceral Pain in Mice by TRPA1-Dependent and -Independent Mechanisms: Role of Tissue Injury and P2X Receptors by Gonzalez-Cano, Rafael, Montilla-García, Ángeles, Perazzoli, Gloria, Torres, Jesús M, Cañizares, Francisco J, Fernández-Segura, Eduardo, Costigan, Michael, Baeyens, José M, Cobos, Enrique J

“…Both TRPA1 and purinergic P2X receptors have been proposed as potential targets for the treatment of visceral pain. We found that the intracolonic…”
Get full text

Changes in intracellular sodium, chlorine, and potassium concentrations in staurosporine-induced apoptosis by Arrebola, Francisco, Zabiti, Saloua, Cañizares, Francisco J., Cubero, Maria A., Crespo, Pascual V., Fernández-Segura, Eduardo

“…Ion gradients across the plasma membrane, fundamentally K+, play a pivotal role in the execution phase of apoptosis. However, little is known about other…”
Get full text

SIGMA-1 RECEPTOR AGONISM EXACERBATES IMMUNE-DRIVEN NOCICEPTION: ROLE OF TRPV1+ NOCICEPTORS by Ruiz-Cantero, Mari Carmen, Huerta, Miguel Ángel, Tejada, Miguel Á., Fernández-Segura, Eduardo, Cañizares, Francisco J., Baeyens, José Manuel, Cobos, Enrique J.

Get full text

Improvement of the antioxidant and hypolipidaemic effects of cowpea flours ( Vigna unguiculata ) by fermentation: results of in vitro and in vivo experiments: Health benefits of raw and fermented V. unguiculata by Kapravelou, Garyfallia, Martínez, Rosario, Andrade, Ana M, López Chaves, Carlos, López-Jurado, María, Aranda, Pilar, Arrebola, Francisco, Cañizares, Francisco J, Galisteo, Milagros, Porres, Jesús M

Get full text

Changes in Elemental Content During Apoptotic Cell Death Studied by Electron Probe X-Ray Microanalysis by Fernández-Segura, Eduardo, Cañizares, Francisco J., Cubero, Maria A., Warley, Alice, Campos, Antonio

“…Recent data suggest that changes in ionic content, primarily potassium, play a pivotal role in the progression of apoptosis. However, the changes in total…”
Get full text