Search Results - "CUSTER, R. P"

Evidence of functional lymphocytes in some (leaky) scid mice by BOSMA, G. C, FRIED, M, CUSTER, R. P, CARROLL, A, GIBSON, D. M, BOSMA, M. J

“…Although the majority of severe combined immune deficiency (scid) mice lack functional lymphocytes, some (2-23%) appear to develop a limited number of B and T…”
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Severe combined immunodeficiency (SCID) in the mouse. Pathology, reconstitution, neoplasms by Custer, RP, Bosma, GC, Bosma, MJ

“…Histologic findings in mice with severe combined immunodeficiency (SCID) were remarkably uniform, consisting of lymphopenia, a rudimentary thymic medulla…”
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Target Polypeptide of a Carcinogen is Associated with Normal Mitosis and Carcinogen-Induced Hyperplasias in Adult Hepatocytes by Custer, R. Philip, Sorof, Sam

“…Normal rat liver cytosol was found previously to contain a 14,000-dalton polypeptide that is the principal target of the carcinogen N-2-fluorenylacetamide…”
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Iron, ferritin, hepatitis B surface and core antigens in the livers of Chinese patients with hepatocellular carcinoma by Zhou, X D, DeTolla, L, Custer, R P, London, W T

“…Surgically resected specimens, consisting of tumor and adjacent non-neoplastic liver tissue, were obtained from 40 patients with primary liver cancer at Zhong…”
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Elevated expression and cell cycle deregulation of a mitosis-associated target polypeptide of a carcinogen in hyperplastic and malignant rat hepatocytes by SOROF, S, CUSTER, R. P

“…A cytoplasmic polypeptide with a molecular weight of 14,000 (p14) was previously found to be the principal covalent target protein of the carcinogen,…”
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Totipotent hematopoietic stem cells: normal self-renewal and differentiation after transplantation between mouse fetuses by Fleischman, R A, Custer, R P, Mintz, B

“…Successful engraftment of mouse fetal liver cells in early fetal recipients, after microinjection via the placental circulation, is attributable to seeding of…”
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Retinoid Prevents Mammary Gland Transformation by Carcinogenic Hydrocarbon in Whole-Organ Culture by Dickens, Michael S., Custer, R. Philip, Sorof, Sam

“…The mouse mammary gland in whole-organ culture, an in vitro system that is capable of alveolar development, differentiation, involution, and oncogenic…”
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Persistence of precursor cells of squamous metaplasia in preneoplastic mammary outgrowth lines from mice by Schaefer, F V, Custer, R P, Sorof, S

“…The preneoplastic state is without apparent effect on the induction or prevention of epidermidalization in transplanted mammary outgrowth lines. Development of…”
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Mitosis in hepatocytes is generally associated with elevated levels of the target polypeptide of a liver carcinogen by Custer, R P, Sorof, S

“…Rat hepatocytes have previously been found to contain in their cytoplasm a 14,000-dalton polypeptide that: is markedly and specifically increased in…”
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Normal Liver Chromatin Contains a Firmly Bound and Larger Protein Related to the Principal Cytosolic Target Polypeptide of a Hepatic Carcinogen by Vinores, Stanley A., Churey, John J., Haller, Joanne M., Schnabel, Susan J., Custer, R. Philip, Sorof, Sam

“…A 14,000-dalton polypeptide was previously reported to be the principal protein target of the carcinogen N-2-fluorenylacetamide (2-acetylaminofluorene) in…”
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Normal hepatocytes exhibiting histone H3 with antibody accessible sites that are cryptic in carcinogen-altered hepatocytes by MUNIR, K. M, CUSTER, R. P, SAM SOROF

“…A Mr 14,000 polypeptide (p14), identified as liver fatty acid binding protein, in normal liver cytosol was shown previously to be the principal target of the…”
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Reconstitution of scid mice by injection of varying numbers of normal fetal liver cells into scid neonates by Bosma, G C, Gibson, D M, Custer, R P, Bosma, M J

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Growth of human normal and neoplastic mammary tissues in the cleared mammary fat pad of the nude mouse by Outzen, H C, Custer, R P

“…Dysplastic and malignant human breast tissues were grown successfully in the cleared mammary fat pads (CFP) of nude mice. The mammary fat pads were cleared…”
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A severe combined immunodeficiency mutation in the mouse by Bosma, Gayle C, Custer, R. Philip, Bosma, Melvin J

“…The most debilitating human lymphoid deficiency disease, known as severe combined immunodeficiency (SCID), impairs the differentiation of both T and B…”
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Dystrophic cardiac calcinosis in mice: genetic, hormonal, and dietary influences by Eaton, G J, Custer, R P, Johnson, F N, Stabenow, K T

“…Mice of five inbred strains (BALB/c, C3H, C3Hf, DBA/2, and C57BL/6) of both sexes, mated and virginal, were examined for the incidence, severity, and location…”
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Induction of epidermoid differentiation by cyclic adenine nucleotide in cultured mammary tumors of mice by SCHAEFER, F. V, CUSTER, R. P, SOROF, S

“…In search of the degree of responsiveness of mammary adenocarcinomas to signals of differentiation, mouse mammary tumors were induced to undergo a course of…”
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Somatic Cell Origin of Teratocarcinomas by Mintz, Beatrice, Cronmiller, Claire, Custer, R. Philip

“…Malignant teratocarcinomas arise from developmentally totipotent normal stem cells. Whether the targets are embryonal somatic cells or germinal cells has long…”
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Induction of squamous metaplasia: requirement for cell multiplication, and competition with lobuloalveolar development in cultured mammary glands by Schaefer, F V, Custer, R P, Sorof, S

“…Mouse mammary glands were previously shown to undergo either of two courses of development and differentiation in whole organ culture. The combination of…”
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Differentiation of a methylcholanthrene-induced sarcoma to a benign plexiform fibroneural tumor in an adult frog (Rana pipiens). Possible influence of host regenerative capacity by Outzen, HC, Custer, RP

“…A spindle cell sarcoma appeared 20 months after implantation of a pellet of 3-methylcholanthrene in the denervated foreleg of an adult frog, Rana pipiens. Its…”
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Nononcogenic hormone-independent alveoli produced by carcinogens in cultured mouse mammary glands by SCHAEFER, F. V, TONELLI, Q. J, DICKENS, M. S, CUSTER, R. P, SOROF, S

“…Treatment of mouse mammary glands with a high concentration of 7,12-dimethylbenzo(a)anthracene in whole organ culture was reported by Banerjee et al. to…”
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