Search Results - "CUNNINGHAM, Charles"
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Particle‐based MR modeling with diffusion, microstructure, and enzymatic reactions
Published in Magnetic resonance in medicine (01-01-2025)“…Purpose To develop a novel particle‐based in silico MR model and demonstrate applications of this model to signal mechanisms which are affected by the spatial…”
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Statistical Methods for the Analysis of Discrete Choice Experiments: A Report of the ISPOR Conjoint Analysis Good Research Practices Task Force
Published in Value in health (01-06-2016)“…Abstract Conjoint analysis is a stated-preference survey method that can be used to elicit responses that reveal preferences, priorities, and the relative…”
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Analysis of Cancer Metabolism by Imaging Hyperpolarized Nuclei: Prospects for Translation to Clinical Research
Published in Neoplasia (New York, N.Y.) (01-02-2011)“…A major challenge in cancer biology is to monitor and understand cancer metabolism in vivo with the goal of improved diagnosis and perhaps therapy. Because of…”
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Noninvasive Immunometabolic Cardiac Inflammation Imaging Using Hyperpolarized Magnetic Resonance
Published in Circulation research (13-04-2018)“…RATIONALE:Current cardiovascular clinical imaging techniques offer only limited assessment of innate immune cell-driven inflammation, which is a potential…”
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5
Saturated double-angle method for rapid B1+ mapping
Published in Magnetic resonance in medicine (01-06-2006)“…For in vivo magnetic resonance imaging at high field (≥3 T) it is essential to consider the homogeneity of the active B1 field (B1+), particularly if surface…”
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First in‐human evaluation of pyruvate in D2O for hyperpolarized MRI of the brain: A safety and feasibility study
Published in Magnetic resonance in medicine (01-06-2024)“…PurposeTo investigate the safety and value of hyperpolarized (HP) MRI of [1‐13C]pyruvate in healthy volunteers using deuterium oxide (D2O) as a…”
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Age‐associated change in pyruvate metabolism investigated with hyperpolarized 13C‐MRI of the human brain
Published in Human brain mapping (01-07-2023)“…In this study, hyperpolarized 13C MRI (HP‐13C MRI) was used to investigate changes in the uptake and metabolism of pyruvate with age. Hyperpolarized…”
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Hyperpolarized 13C lactate, pyruvate, and alanine: noninvasive biomarkers for prostate cancer detection and grading
Published in Cancer research (Chicago, Ill.) (15-10-2008)“…An extraordinary new technique using hyperpolarized (13)C-labeled pyruvate and taking advantage of increased glycolysis in cancer has the potential to improve…”
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Assessment of the Feasibility of Hyperpolarized [1- 13 C]pyruvate Whole-Abdomen MRI using D 2 O Solvation in Humans
Published in Journal of magnetic resonance imaging (01-12-2024)Get full text
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First in-human evaluation of [1- 13 C]pyruvate in D 2 O for hyperpolarized MRI of the brain: A safety and feasibility study
Published in Magnetic resonance in medicine (01-06-2024)“…To investigate the safety and value of hyperpolarized (HP) MRI of [1- C]pyruvate in healthy volunteers using deuterium oxide (D O) as a solvent. Healthy…”
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What is the mechanism of action of praziquantel and how might resistance strike?
Published in Future medicinal chemistry (01-04-2015)Get full text
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12
DWI of the spinal cord with reduced FOV single-shot EPI
Published in Magnetic resonance in medicine (01-08-2008)“…Single‐shot echo‐planar imaging (ss‐EPI) has not been used widely for diffusion‐weighted imaging (DWI) of the spinal cord, because of the magnetic field…”
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Cardiac metabolic imaging using hyperpolarized [1‐13C]lactate as a substrate
Published in NMR in biomedicine (01-07-2021)“…Hyperpolarized (HP) [1‐13C]lactate is an attractive alternative to [1‐13C]pyruvate as a substrate to investigate cardiac metabolism in vivo: it can be…”
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14
Distinguishing selective mutism and social anxiety in children: a multi-method study
Published in European child & adolescent psychiatry (01-07-2021)“…Selective mutism (SM) is an anxiety disorder in which a child fails to speak in some situations (e.g., school) despite the ability to speak in other situations…”
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Cross‐talk between the bone morphogenetic protein pathway and other major signaling pathways results in tightly regulated cell‐specific outcomes
Published in The FEBS journal (01-06-2007)“…Members of the bone morphogenetic protein (BMP) family of ligands have been identified in a variety of vertebrate and invertebrate species and have been shown…”
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Nonrigid motion correction in 3D using autofocusing withlocalized linear translations
Published in Magnetic resonance in medicine (01-12-2012)“…MR scans are sensitive to motion effects due to the scan duration. To properly suppress artifacts from nonrigid body motion, complex models with elements such…”
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Imaging and treatment of brain tumors through molecular targeting: Recent clinical advances
Published in European journal of radiology (01-09-2021)“…Molecular imaging techniques have rapidly progressed over recent decades providing unprecedented in vivo characterization of metabolic pathways and molecular…”
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Trajectories of Observed Shyness and Psychosocial Adjustment in Children
Published in Child psychiatry and human development (01-08-2020)“…Shyness can manifest as inhibition, fear, and avoidance in the context of social novelty and situations of perceived social evaluation. In the present study,…”
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Comparative Genomics of Carp Herpesviruses
Published in Journal of Virology (01-03-2013)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Evidence of 13C‐lactate oxidation in the human brain from hyperpolarized 13C‐MRI
Published in Magnetic resonance in medicine (01-05-2024)“…Purpose To test the hypothesis that lactate oxidation contributes to the 13$$ {}^{13} $$C‐bicarbonate signal observed in the awake human brain using…”
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