Search Results - "CUMMING, A. M"

Effect of water table management and elevated CO2 on radish productivity and on CH4 and CO2 fluxes from peatlands converted to agriculture by Musarika, S., Atherton, C.E., Gomersall, T., Wells, M.J., Kaduk, J., Cumming, A.M.J., Page, S.E., Oechel, W.C., Zona, D.

“…Anthropogenic activity is affecting the global climate through the release of greenhouse gases (GHGs) e.g. CO2 and CH4. About a third of anthropogenic GHGs are…”
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Maize grown for bioenergy on peat emits twice as much carbon as when grown on mineral soil by Lloyd, I. L., Morrison, R., Grayson, R. P., Cumming, A. M. J., D'Acunha, B., Galdos, M. V., Evans, C. D., Chapman, P. J.

“…The area of land dedicated to growing maize for bioenergy in the United Kingdom is rapidly expanding. To understand how maize production influences soil carbon…”
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Geographic distribution of the 20210 G to A prothrombin variant by Rosendaal, F R, Doggen, C J, Zivelin, A, Arruda, V R, Aiach, M, Siscovick, D S, Hillarp, A, Watzke, H H, Bernardi, F, Cumming, A M, Preston, F E, Reitsma, P H

“…A variant in prothrombin (clotting factor II), a G to A transition at nucleotide position 20210, has recently been shown to be associated with the prothrombin…”
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Evaluation of the use of global haemostasis assays to monitor treatment in factor XI deficiency by Pike, G. N., Cumming, A. M., Thachil, J., Hay, C. R. M., Burthem, J., Bolton‐Maggs, P. H. B.

“…Introduction Previous guidelines recommend that FXI:C levels should be used to monitor FXI replacement in factor XI (FXI) deficiency. However, FXI:C levels do…”
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The prothrombin gene G20210A variant: prevalence in a U.K. anticoagulant clinic population by CUMMING, A. M., KEENEY, S., SALDEN, A., BHAVNANI, M., SHWE, K. H., HAY, C. R. M.

“…We have investigated the prevalence of a recently reported genetic variation in the prothrombin gene (G20210A) in patients with an objectively confirmed…”
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Contribution of APOE promoter polymorphisms to Alzheimer's disease risk by LAMBERT, J.-C, ARARIA-GOUMIDI, L, FRIGARD, B, PETERSEN, R. C, CUMMING, A. M, PASQUIER, F, SASTRE, I, TIENARI, P. J, FRANK, A, SULKAVA, R, MORRIS, J. C, CLAIR, D. St, MYLLYKANGAS, L, MANN, D. M, WAVRANT-DEVRIEZE, F, EZQUERRA-TRABALON, M, AMOUYEL, P, HARDY, J, HALTIA, M, VALDIVIESO, F, GOATE, A. M, PEREZ-TUR, J, LENDON, C. L, ELLIS, C, CHARTIER-HARLIN, M.-C, WANG, J. C, BULLIDO, M. J, HARRIS, J. M, ARTIGA, M. J, HERNANDEZ, D, KWON, J. M

“…To determine whether the effects of APOE promoter polymorphisms on AD are independent of the APOE-epsilon4 allele. Recently, the -491 A-->T and -219 G-->T…”
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Development of resistance to activated protein C during pregnancy by Cumming, A M, Tait, R C, Fildes, S, Yoong, A, Keeney, S, Hay, C R

“…We measured activated protein C (APC) anticoagulant activity in 20 healthy women at 14-20, 28 and 36 weeks gestation, and at 1 d post-partum. Significant…”
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Management of von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors' Organization by Pasi, K. J., Collins, P. W., Keeling, D. M., Brown, S. A., Cumming, A. M., Dolan, G. C., Hay, C. R. M., Hill, F. G. H., Laffan, M., Peake, I. R.

“…von Willebrand disease (VWD) is the commonest inherited bleeding disorder. The aim of therapy for VWD is to correct the two defects of haemostasis in this…”
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The diagnosis of von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors' Organization by Laffan, M., Brown, S. A., Collins, P. W., Cumming, A. M., Hill, F. G. H., Keeling, D., Peake, I. R., Pasi, K. J.

“…von Willebrand disease (VWD) is the commonest inherited bleeding disorder. However, despite an increasing understanding of the pathophysiology of VWD, the…”
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The molecular biology of von Willebrand disease by Keeney, S., Cumming, A.M.

“…von Willebrand disease (VWD) is a common autosomally inherited bleeding disorder associated with mucosal or trauma‐related bleeding in affected individuals…”
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Evaluation of the use of rotational thromboelastometry in the assessment of FXI deficency by Pike, G. N., Cumming, A. M., Thachil, J., Hay, C. R. M., Bolton‐Maggs, P. H. B., Burthem, J.

“…Introduction The absence of a reliable clinical test to predict bleeding tendency leaves factor XI (FXI)‐deficient individuals at risk of overtreatment or…”
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A framework for genetic service provision for haemophilia and other inherited bleeding disorders by Ludlam, C. A., Pasi, K. J., Bolton-Maggs, P., Collins, P. W., Cumming, A. M., Dolan, G., Fryer, A., Harrington, C., Hill, F. G. H., Peake, I. R., Perry, D. J., Skirton, H., Smith, M.

“…This framework document offers guidance to patients, doctors, nurses, laboratory scientists, funders and hospitals on the provision of clinical and laboratory…”
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Human leucocyte antigen-A2 increases risk of Alzheimer's disease but does not affect age of onset in a Scottish population by Harris, J.M, Cumming, A.M, Craddock, N, St Clair, D, Lendon, C.L

“…The use of non-steroidal anti-inflammatory drugs has been associated with a reduced incidence of Alzheimer's disease (AD), suggesting that attenuation of the…”
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In vitro comparison of the effect of two factor XI (FXI) concentrates on thrombin generation in major FXI deficiency by Pike, G. N., Cumming, A. M., Hay, C. R. M., Sempasa, B., Sutherland, M., Thachil, J., Burthem, J., Bolton-Maggs, P. H. B.

“…Introduction Bleeding risk in factor XI (FXI) deficiency following surgery may be reduced by treatment with either of two FXI concentrates, but indications for…”
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The investigation and management of inherited thrombophilia by Cumming, A. M., Shiach, C. R.

“…Inherited thrombophilia can be defined as a genetically determined tendency to venous thromboembolism. Genetic risk factors for venous thrombosis include…”
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The factor VIII gene intron 1 inversion mutation: prevalence in severe hemophilia A patients in the UK by Cumming, A. M.

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The C677T MTHFR variant and the risk of venous thrombosis by Salden, A, Keeney, S, Hay, C R, Cumming, A M

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The mutation spectrum associated with type 3 von Willebrand disease in a cohort of patients from the North West of England by SUTHERLAND, M. S., KEENEY, S., BOLTON-MAGGS, P. H. B., HAY, C. R. M., WILL, A., CUMMING, A. M.

“…Type 3 von Willebrand disease (VWD) is a severe autosomal recessive inherited bleeding disorder. In affected individuals the underlying von Willebrand factor…”
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The methylenetetrahydrofolate reductase gene C677T polymorphism in patients with homozygous sickle cell disease and stroke by CUMMING, A. M, OLUJOHUNGBE, A, KEENEY, S, SINGH, H, HAY, C. R. M, SERJEANT, G. R

“…Homozygosity for the methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism may cause hyperhomocysteinaemia, a recognized risk factor for stroke,…”
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Type 1 von Willebrand disease: application of emerging data to clinical practice by COLLINS, P. W., CUMMING, A. M., GOODEVE, A. C., LILLICRAP, D.

“…There has been much recent data published on type 1 von Willebrand disease (VWD) predominantly from three multi‐centre cohort studies. These data have…”
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