Search Results - "CULL, Vanessa S"
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Type I interferon gene therapy protects against cytomegalovirus‐induced myocarditis
Published in Immunology (01-07-2002)“…Summary Type I interferons (IFNs) are produced early in response to viral infection and modulate adaptive immunity. Previously we demonstrated localized…”
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Synergy of type I interferon-A6 and interferon-B naked DNA immunotherapy for cytomegalovirus infection
Published in Immunology and cell biology (01-10-2002)“…Delivery of type I IFN transgenes by naked DNA immunization can protect against cytomegalovirus infection and myocarditis. Here, we investigate IFN transgene…”
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Type I interferon differential therapy for erythroleukemia: specificity of STAT activation
Published in Blood (01-04-2003)“…Type I interferons (IFNs), pleiotropic cytokines with antiviral, antiproliferative, apoptotic, and immunoregulatory functions, are efficacious in the treatment…”
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Optimization of Naked DNA Delivery for Interferon Subtype Immunotherapy in Cytomegalovirus Infection
Published in Biological procedures online (2003)“…Type I interferon (IFN) gene therapy modulates the immune response leading to inflammatory heart disease following cytomegalovirus (CMV) infection in a murine…”
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5
Maturation of erythroid cells and erythroleukemia development are affected by the kinase activity of Lyn
Published in Cancer research (Chicago, Ill.) (15-03-2001)“…This study examined the impact of the tyrosine kinase Lyn on erythropoietin-induced intracellular signaling in erythroid cells. In J2E erythroleukemic cells,…”
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Type I IFN‐β gene therapy suppresses cardiac CD8+ T‐cell infiltration during autoimmune myocarditis
Published in Immunology and cell biology (01-04-2004)“…Gene therapy using DNA encoding type I IFN subtypes IFNA6, IFNA9 and IFNB suppresses murine cytomegalovirus (MCMV)‐myocarditis, a predominantly cell‐mediated…”
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Differential regulation of SOCS genes in normal and transformed erythroid cells
Published in Oncogene (22-05-2003)“…The SOCS family of genes are negative regulators of cytokine signalling with SOCS-1 displaying tumor suppressor activity. SOCS-1, CIS and SOCS-3 have been…”
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Cytokine expression in murine cytomegalovirus-induced myocarditis: modulation with interferon-α therapy
Published in Cellular immunology (01-05-2003)“…Cytomegalovirus-induced myocarditis is largely immune-mediated. BALB/c mice produced higher levels of IL-4 in the heart indicative of a Th2-like response…”
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Interferon subtype gene therapy for regulating cytomegalovirus disease
Published in Methods in molecular medicine (2005)“…Delivery of type I interferon (IFN) subtypes by intramuscular inoculation of mice with a recombinant mammalian expression vector encoding IFN stimulates the…”
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Type I IFN- gene therapy suppresses cardiac CD8 T-cell infiltration during autoimmune myocarditis
Published in Immunology and cell biology (01-04-2004)“…SummaryGene therapy using DNA encoding type I IFN subtypes IFNA6, IFNA9 and IFNB suppresses murine cytomegalovirus (MCMV)-myocarditis, a predominantly…”
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Amiloride Suppresses Erythropoietin-Induced Proliferation and MAP Kinase, but Potentiates Differentiation of J2E Cells
Published in Experimental cell research (01-07-1995)“…The J2E erythroid cell line proliferates and differentiates in response to erythropoietin (epo). Here we demonstrate that the diuretic amiloride can suppress…”
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