Search Results - "CUIQING MA"
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Biotechnological routes based on lactic acid production from biomass
Published in Biotechnology advances (01-11-2011)“…Lactic acid, the most important hydroxycarboxylic acid, is now commercially produced by the fermentation of sugars present in biomass. In addition to its use…”
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Receptor usage and cell entry of bat coronavirus HKU4 provide insight into bat-to-human transmission of MERS coronavirus
Published in Proceedings of the National Academy of Sciences - PNAS (26-08-2014)“…Middle East respiratory syndrome coronavirus (MERS-CoV) currently spreads in humans and causes ∼36% fatality in infected patients. Believed to have originated…”
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3
An l-2-hydroxyglutarate biosensor based on specific transcriptional regulator LhgR
Published in Nature communications (15-06-2021)“…l -2-Hydroxyglutarate ( l- 2-HG) plays important roles in diverse physiological processes, such as carbon starvation response, tumorigenesis, and hypoxic…”
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4
From SARS-CoV to SARS-CoV-2: safety and broad-spectrum are important for coronavirus vaccine development
Published in Microbes and infection (01-07-2020)“…The global pandemic of COVID-19 caused by SARS-CoV-2 (also known as 2019-nCoV and HCoV-19) has posed serious threats to public health and economic stability…”
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A d-2-hydroxyglutarate biosensor based on specific transcriptional regulator DhdR
Published in Nature communications (07-12-2021)“…d -2-Hydroxyglutarate ( d -2-HG) is a metabolite involved in many physiological metabolic processes. When d -2-HG is aberrantly accumulated due to mutations in…”
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6
Degradation of n-alkanes and polycyclic aromatic hydrocarbons in petroleum by a newly isolated Pseudomonas aeruginosa DQ8
Published in Bioresource technology (01-03-2011)“…A bacterial isolate, designated as DQ8, was found capable of degrading diesel, crude oil, n-alkanes and polycyclic aromatic hydrocarbons (PAHs) in petroleum…”
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Microbial lactate utilization: enzymes, pathogenesis, and regulation
Published in Trends in microbiology (Regular ed.) (01-10-2014)“…Highlights • We provide a categorization of NAD-independent lactate dehydrogenases (iLDHs). • We introduce how iLDHs are applied in industry and human life. •…”
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Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitor
Published in Nature communications (28-01-2014)“…A novel human coronavirus, Middle East respiratory syndrome coronavirus (MERS-CoV), has caused outbreaks of a SARS-like illness with high case fatality rate…”
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9
Respiratory Syncytial Virus Replication Is Promoted by Autophagy-Mediated Inhibition of Apoptosis
Published in Journal of virology (15-04-2018)“…Respiratory syncytial virus (RSV) is the main cause of acute lower respiratory tract infection (ALRI) in children worldwide. Virus-host interactions affect the…”
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Organoids: new frontiers in tumor immune microenvironment research
Published in Frontiers in immunology (29-07-2024)“…The tumor microenvironment (TME) contains cells that regulate medication response and cancer growth in a major way. Tumor immunology research has been…”
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Co-utilization of glycerol and lignocellulosic hydrolysates enhances anaerobic 1,3-propanediol production by Clostridium diolis
Published in Scientific reports (11-01-2016)“…Anaerobic fermentation using lignocellulosic hydrolysates as co-substrates is an economically attractive method to enhance 1,3-propanediol (1,3-PD) production…”
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Systematic metabolic engineering of Escherichia coli for high-yield production of fuel bio-chemical 2,3-butanediol
Published in Metabolic engineering (01-05-2014)“…The production of biofuels by recombinant Escherichia coli is restricted by the toxicity of the products. 2,3-Butanediol (2,3-BD), a platform and fuel…”
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Butanol production by Clostridium beijerinckii ATCC 55025 from wheat bran
Published in Journal of industrial microbiology & biotechnology (01-05-2010)“…Wheat bran, a by-product of the wheat milling industry, consists mainly of hemicellulose, starch and protein. In this study, the hydrolysate of wheat bran…”
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A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccines
Published in PloS one (04-12-2013)“…An emerging respiratory infectious disease with high mortality, Middle East respiratory syndrome (MERS), is caused by a novel coronavirus (MERS-CoV). It was…”
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Use of machine learning-based integration to develop a monocyte differentiation-related signature for improving prognosis in patients with sepsis
Published in Molecular medicine (Cambridge, Mass.) (20-03-2023)“…Although significant advances have been made in intensive care medicine and antibacterial treatment, sepsis is still a common disease with high mortality. The…”
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Efficient production of 2,3-butanediol from corn stover hydrolysate by using a thermophilic Bacillus licheniformis strain
Published in Bioresource technology (01-10-2014)“…•Thermophilic Bacillus licheniformis X10 utilizes glucose and xylose simultaneously.•B. licheniformis X10 tolerates up to 3g/L of furfural, vanillin, or formic…”
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Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines
Published in Vaccine (11-04-2014)“…Highlights • We compared MERS-CoV RBD-induced immune responses via i.n. and s.c. routes. • I.n. induced comparable systemic humoral immune responses as s.c. •…”
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Searching for an ideal vaccine candidate among different MERS coronavirus receptor-binding fragments—The importance of immunofocusing in subunit vaccine design
Published in Vaccine (21-10-2014)“…Highlights • We express five MERS-CoV RBDs spanning S350-588, 358-588, 367-588, 377-606, and 377-588. • S377-588, 367-588 and 358-588 have the highest receptor…”
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Rab5c promotes RSV and ADV replication by autophagy in respiratory epithelial cells
Published in Virus research (01-03-2024)“…•The activated Rab5c promotes RSV and ADV replication and the inactivated Rab5c inhibits their replication.•Rab5c promoting RSV and ADV replication is not…”
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Metabolic engineering of Enterobacter cloacae for high-yield production of enantiopure (2R,3R)-2,3-butanediol from lignocellulose-derived sugars
Published in Metabolic engineering (01-03-2015)“…Biotechnological production of biofuels is restricted by toxicity of the products such as ethanol and butanol. As its low toxicity to microbes, 2,3-butanediol…”
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