Search Results - "CRUSIO, W. E"

Functional implications of decreases in neurogenesis following chronic mild stress in mice by Mineur, Y.S, Belzung, C, Crusio, W.E

“…Abstract Numerous data from human and animal studies suggest that hippocampal plasticity might be a key element in depression. However, the connection remains…”
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Standards for the publication of mouse mutant studies by Crusio, W. E., Goldowitz, D., Holmes, A., Wolfer, D.

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Monogenic mouse models of social dysfunction: Implications for autism by Oddi, D., Crusio, W.E., D’Amato, F.R., Pietropaolo, S.

“…► The Fmr1- and mu-KO mouse lines present clear autistic-like phenotypes. ► Both models must be further investigated especially for sex and age differences. ►…”
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Gene-targeting studies: new methods, old problems by Crusio, Wim E

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QTL and systems genetics analysis of mouse grooming and behavioral responses to novelty in an open field by Delprato, A., Algéo, M.‐P., Bonheur, B., Bubier, J. A., Lu, L., Williams, R. W., Chesler, E. J., Crusio, W. E.

“…The open field is a classic test used to assess exploratory behavior, anxiety and locomotor activity in rodents. Here, we mapped quantitative trait loci (QTLs)…”
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A note on the effect of within‐strain sample sizes on QTL mapping in recombinant inbred strain studies by Crusio, W. E.

“…This note explores the effect of within‐strain sample sizes on the correlations between a phenotype and a molecular‐genetic marker in a battery of inbred…”
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Books in short by Crusio, W. E.

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A quantitative trait locus on chromosome 1 modulates intermale aggression in mice by Delprato, A., Bonheur, B., Algéo, M.‐P., Murillo, A., Dhawan, E., Lu, L., Williams, R. W., Crusio, W. E.

“…Aggression between male conspecifics is a complex social behavior that is likely modulated by multiple gene variants. In this study, the BXD recombinant inbred…”
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Systems genetic analysis of hippocampal neuroanatomy and spatial learning in mice by Delprato, A., Bonheur, B., Algéo, M.‐P., Rosay, P., Lu, L., Williams, R. W., Crusio, W. E.

“…Variation in hippocampal neuroanatomy correlates well with spatial learning ability in mice. Here, we have studied both hippocampal neuroanatomy and behavior…”
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Hippocampal mossy fibers and radial-maze learning in the mouse: a correlation with spatial working memory but not with non-spatial reference memory by Schwegler, H, Crusio, W E, Brust, I

“…One hundred and eight male mice from nine different inbred strains were tested for two aspects of learning in an eight-arm radial maze. In the first…”
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Correlations between radial-maze learning and structural variations of septum and hippocampus in rodents by Schwegler, Herbert, Crusio, Wim E.

“…Large, but non-pathological, individual differences in neuroanatomy of the brain exist in rodents, which have been shown to covary with behavioral traits. In…”
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Flanking gene and genetic background problems in genetically manipulated mice by Crusio, Wim E.

“…Mice carrying engineered genetic modifications have become an indispensable tool in the study of gene functioning. The interpretation of results obtained with…”
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Radial-maze performance and structural variation of the hippocampus in mice: a correlation with mossy fibre distribution by Crusio, W E, Schwegler, H, Lipp, H P

“…Twenty-four male mice, belonging to 8 different inbred strains, were tested in an 8-arm radial maze. Clear strain differences were found for performance on the…”
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Further phenotypical characterisation of two substrains of C57BL/6J inbred mice differing by a spontaneous single-gene mutation by SLUYTER, F, MARICAN, C. C. M, CRUSIO, W. E

“…Males from two substrains of C57BL/6J mice, which have been found to differ for open-field exploration, radial-maze learning, and the sizes of their…”
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Social behavior deficits in the Fmr1 mutant mouse by Mineur, Yann S., Huynh, Linh X., Crusio, Wim E.

“…Mice exhibiting deficits in social behavior may provide valuable models for autistic-like behavioral problems. We tested social interactions in male mice from…”
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Genetic dissection of mouse exploratory behaviour by Crusio, Wim E

“…A large variety of apparatus and procedures are being employed to measure mouse exploratory behaviour. Definitions of what constitutes exploration also vary…”
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13-cis-Retinoic Acid Suppresses Hippocampal Cell Division and Hippocampal-Dependent Learning in Mice by Crandall, James, Sakai, Yasuo, Zhang, Jinghua, Koul, Omanand, Mineur, Yann, Crusio, Wim E., McCaffery, Peter, Dowling, John E.

“…The active component of the acne drug Accutane is 13-cis-retinoic acid (RA), and it is highly teratogenic for the developing central nervous system. Very…”
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Knockout mice: simple solutions to the problems of genetic background and flanking genes by Wolfer, David P., Crusio, Wim E., Lipp, Hans-Peter

“…Inducing null mutations by means of homologous recombination provides a powerful technique to investigate gene function and has found wide application in many…”
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The genetic dissection of brain-behaviour relationships An introduction to neurobehavioural genetics by Crusio, W E

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Radial maze learning in two inbred mouse strains and their reciprocal congenics for the non-pseudoautosomal region of the Y chromosome by Sluyter, Frans, Marican, Charlotte C.M., Roubertoux, Pierre L., Crusio, W.E.

“…The effect of the non-pseudoautosomal region of the Y chromosome on spatial learning in a radial maze task was examined in two inbred mouse strains, NZB and…”
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