Search Results - "CROWLEY, W. F. JR"

Kisspeptin and GPR54: Discovery of a Novel Pathway in Reproduction by Seminara, S. B., Crowley Jr, W. F.

“…In order to find novel modulators of gonadotrophin‐releasing hormone (GnRH) secretion, genetic tools were employed in patients with idiopathic…”
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Signaling role of prokineticin 2 on the estrous cycle of female mice by Xiao, Ling, Zhang, Chengkang, Li, Xiaohan, Gong, Shiaoching, Hu, Renming, Balasubramanian, Ravikumar, Crowley W, Jr, William F, Hastings, Michael H, Zhou, Qun-Yong

“…The possible signaling role of prokineticin 2 (PK2) and its receptor, prokineticin receptor 2 (PKR2), on female reproduction was investigated. First, the…”
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CHD7 mutations in patients initially diagnosed with Kallmann syndrome - the clinical overlap with CHARGE syndrome by Jongmans, MCJ, Van Ravenswaaij-Arts, CMA, Pitteloud, N, Ogata, T, Sato, N, Claahsen-van der Grinten, HL, Van Der Donk, K, Seminara, S, Bergman, JEH, Brunner, HG, Crowley Jr, WF, Hoefsloot, LH

“…Kallmann syndrome (KS) is the combination of hypogonadotropic hypogonadism and anosmia or hyposmia, two features that are also frequently present in CHARGE…”
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Increases in bone density during treatment of men with idiopathic hypogonadotropic hypogonadism by Finkelstein, J S, Klibanski, A, Neer, R M, Doppelt, S H, Rosenthal, D I, Segre, G V, Crowley, Jr, W F

“…To assess the effects of gonadal steroid replacement on bone density in men with osteoporosis due to severe hypogonadism, we measured cortical bone density in…”
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Hyperfunction of the hypothalamic-pituitary axis in women with polycystic ovarian disease: indirect evidence for partial gonadotroph desensitization by Waldstreicher, J, Santoro, N F, Hall, J E, Filicori, M, Crowley, Jr, W F

“…To examine gonadotropin secretory frequency as a component of the disordered neuroendocrine regulation of gonadotropin secretion in women with polycystic…”
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Characterization of the physiological pattern of episodic gonadotropin secretion throughout the human menstrual cycle by Filicori, M, Santoro, N, Merriam, G R, Crowley, Jr, W F

“…To characterize the spectrum of pulsatile gonadotropin secretion during the course of the normal menstrual cycle, we studied normal women during 51 ovulatory…”
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Changes in growth and serum growth hormone and plasma somatomedin-C levels during suppression of gonadal sex steroid secretion in girls with central precocious puberty by Mansfield, M J, Rudlin, C R, Crigler, Jr, J F, Karol, K A, Crawford, J D, Boepple, P A, Crowley, Jr, W F

“…Suppression of gonadal sex steroid secretion in children with central precocious puberty (CPP) by LHRH analogs affords an opportunity to study sex steroid…”
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The spectrum of abnormal patterns of gonadotropin-releasing hormone secretion in men with idiopathic hypogonadotropic hypogonadism: clinical and laboratory correlations by Spratt, D I, Carr, D B, Merriam, G R, Scully, R E, Rao, P N, Crowley, Jr, W F

“…Several lines of evidence indicate that hypothalamic-pituitary-gonadal activity varies among men with idiopathic hypogonadotropic hypogonadism (IHH). To test…”
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Effects of increasing the frequency of low doses of gonadotropin-releasing hormone (GnRH) on gonadotropin secretion in GnRH-deficient men by Spratt, D I, Finkelstein, J S, Butler, J P, Badger, T M, Crowley, Jr, W F

“…The effects of increasing the frequency of pulsatile GnRH administration on LH and FSH responsiveness were studied in five GnRH-deficient men who had achieved…”
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Evidence of differential control of FSH and LH secretion by gonadotropin-releasing hormone (GnRH) from the use of a GnRH antagonist by Hall, J E, Brodie, T D, Badger, T M, Rivier, J, Vale, W, Conn, P M, Schoenfeld, D, Crowley, Jr, W F

“…The differential regulation of immunoactive FSH and LH secretion by endogenous GnRH was studied using a GnRH antagonist, [Ac-D2Nal1,D4FPhe2,DTrp3,DArg6]GnRH…”
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Normal structure of the gonadotropin-releasing hormone (GnRH) gene in patients with GnRH deficiency and idiopathic hypogonadotropic hypogonadism by Weiss, J, Crowley, Jr, W F, Jameson, J L

“…Idiopathic hypogonadotropic hypogonadism (IHH) is a genetic disorder in which a lack of hypothalamic GnRH secretion forms the basis for impaired gonadotropin…”
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Gonadotropin-Releasing Hormone and Its Analogues by Conn, P. Michael, Crowley, William F

“…RESEARCH into the neuroendocrine control of reproduction by gonadotropin-releasing hormone (GnRH) has witnessed a remarkable two decades. From the isolation…”
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The physiology of gonadotropin-releasing hormone (GnRH) secretion in men and women by Crowley, Jr, W F, Filicori, M, Spratt, D I, Santoro, N F

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Gonadotropin and alpha-subunit responses to chronic gonadotropin-releasing hormone analog administration in patients with glycoprotein hormone-secreting pituitary tumors by Klibanski, A, Jameson, J L, Biller, B M, Crowley, Jr, W F, Zervas, N T, Rivier, J, Vale, W W, Bikkal, H

“…Pituitary tumors secreting intact glycoprotein hormones (LH, FSH, and TSH) and/or alpha-subunit are being increasingly recognized. Because chronic…”
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Validation of highly specific and sensitive radioimmunoassays for lutropin, follitropin, and free alpha subunit in unextracted urine by Landy, H, Schneyer, A L, Whitcomb, R W, Crowley, Jr, W F

“…Measurement of the urinary excretion of lutropin (LH) and follitropin (FSH) and their common free alpha subunit (FAS) assists in monitoring the maturation of…”
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Osteoporosis in men with idiopathic hypogonadotropic hypogonadism by Finkelstein, J S, Klibanski, A, Neer, R M, Greenspan, S L, Rosenthal, D I, Crowley, Jr, W F

“…To assess the effect of testosterone deficiency on skeletal integrity in men, we determined bone density in 23 hypogonadal men with isolated…”
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Improved measurement of free alpha subunit of glycoprotein hormones by assay with use of a monoclonal antibody by Whitcomb, R W, Sangha, J S, Schneyer, A L, Crowley, Jr, W F

“…Any exploration of the physiology of secretion of free alpha subunit of glycoprotein hormones in humans requires a sensitive assay system that shows low cross…”
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The effects of continuous androgen secretion on the hypothalamic-pituitary axis in woman: evidence from a luteinized thecoma of the ovary by Dunaif, A, Scully, R E, Andersen, R N, Chapin, D S, Crowley, Jr, W F

“…Hyperandrogenic states in women are often accompanied by disruption of gonadotropin secretion. However, the role of androgens per se in the pathogenesis of…”
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Decreased Release of Gonadotropin-Releasing Hormone During the Preovulatory Midcycle Luteinizing Hormone Surge in Normal Women by Hall, Janet E., Taylor, Ann E., Martin, Kathryn A., Rivier, Jean, Schoenfeld, David A., Crowley, William F.

“…To investigate the contribution of hypothalamic gonadotropin-releasing hormone (GnRH) secretion to the midcycle gonadotropin surge in the human, the response…”
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Hypogonadotropic disorders in men and women: diagnosis and therapy with pulsatile gonadotropin-releasing hormone by Santoro, N, Filicori, M, Crowley, Jr, W F

“…Hypogonadotropic hypogonadism (HH) is a clinical syndrome occurring in both sexes which has long puzzled clinicians due to the apparent paradox of…”
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