Search Results - "CROS, Jérôme"

Stratification of Pancreatic Ductal Adenocarcinomas Based on Tumor and Microenvironment Features by Puleo, Francesco, Nicolle, Rémy, Blum, Yuna, Cros, Jérôme, Marisa, Laetitia, Demetter, Pieter, Quertinmont, Eric, Svrcek, Magali, Elarouci, Nabila, Iovanna, Juan, Franchimont, Denis, Verset, Laurine, Galdon, Maria Gomez, Devière, Jacques, de Reyniès, Aurélien, Laurent-Puig, Pierre, Van Laethem, Jean-Luc, Bachet, Jean-Baptiste, Maréchal, Raphaël

“…Genomic studies have revealed subtypes of pancreatic ductal adenocarcinoma (PDA) based on their molecular features, but different studies have reported…”
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Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma by Neuzillet, Cindy, Tijeras‐Raballand, Annemilaï, Ragulan, Chanthirika, Cros, Jérôme, Patil, Yatish, Martinet, Matthieu, Erkan, Mert, Kleeff, Jörg, Wilson, Jeremy, Apte, Minoti, Tosolini, Marie, Wilson, Abigail S, Delvecchio, Francesca R, Bousquet, Corinne, Paradis, Valérie, Hammel, Pascal, Sadanandam, Anguraj, Kocher, Hemant M

“…Cancer‐associated fibroblasts (CAF) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Stromal heterogeneity may explain…”
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Telomerase Activation and ATRX Mutations Are Independent Risk Factors for Metastatic Pheochromocytoma and Paraganglioma by Job, Sylvie, Draskovic, Irena, Burnichon, Nelly, Buffet, Alexandre, Cros, Jérôme, Lépine, Charles, Venisse, Annabelle, Robidel, Estelle, Verkarre, Virginie, Meatchi, Tchao, Sibony, Mathilde, Amar, Laurence, Bertherat, Jérôme, de Reyniès, Aurélien, Londoño-Vallejo, Arturo, Favier, Judith, Castro-Vega, Luis Jaime, Gimenez-Roqueplo, Anne-Paule

“…Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors. Whereas most PPGLs are benign, up to 20% may become metastatic with - and -mutated…”
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Periostin‐ and podoplanin‐positive cancer‐associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma by Neuzillet, Cindy, Nicolle, Rémy, Raffenne, Jérôme, Tijeras‐Raballand, Annemilaï, Brunel, Alexia, Astorgues‐Xerri, Lucile, Vacher, Sophie, Arbateraz, Floriane, Fanjul, Marjorie, Hilmi, Marc, Samain, Rémi, Klein, Christophe, Perraud, Aurélie, Rebours, Vinciane, Mathonnet, Muriel, Bièche, Ivan, Kocher, Hemant, Cros, Jérôme, Bousquet, Corinne

“…Cancer‐associated fibroblasts (CAFs) are orchestrators of the pancreatic ductal adenocarcinoma (PDAC) microenvironment. Previously we described four CAF…”
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Erythrocyte-encapsulated asparaginase (eryaspase) combined with chemotherapy in second-line treatment of advanced pancreatic cancer: An open-label, randomized Phase IIb trial by Hammel, Pascal, Fabienne, Portales, Mineur, Laurent, Metges, Jean-Philippe, Andre, Thierry, De La Fouchardiere, Christelle, Louvet, Christophe, El Hajbi, Farid, Faroux, Roger, Guimbaud, Rosine, Tougeron, David, Bouche, Olivier, Lecomte, Thierry, Rebischung, Christine, Tournigand, Christophe, Cros, Jerome, Kay, Richard, Hamm, Adam, Gupta, Anu, Bachet, Jean-Baptiste, El Hariry, Iman

“…This Phase IIb (NCT02195180) open-label study evaluated erythrocyte-encapsulated asparaginase (eryaspase) in combination with chemotherapy in second-line…”
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Role of the fatty pancreatic infiltration in pancreatic oncogenesis by Frendi, Sonia, Martineau, Chloé, Cazier, Hélène, Nicolle, Rémy, Chassac, Anaïs, Albuquerque, Miguel, Raffenne, Jérôme, Le Faouder, Julie, Paradis, Valérie, Cros, Jérôme, Couvelard, Anne, Rebours, Vinciane

“…Although pancreatic precancerous lesions are known to be related to obesity and fatty pancreatic infiltration, the mechanisms remain unclear. We assessed the…”
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Therapeutic advances in metastatic pancreatic cancer: a focus on targeted therapies by Turpin, Anthony, Neuzillet, Cindy, Colle, Elise, Dusetti, Nelson, Nicolle, Rémy, Cros, Jérôme, de Mestier, Louis, Bachet, Jean-Baptiste, Hammel, Pascal

“…Mortality from pancreatic ductal adenocarcinoma (PDAC) is increasing worldwide and effective new treatments are urgently needed. The current treatment of…”
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Establishment of a pancreatic adenocarcinoma molecular gradient (PAMG) that predicts the clinical outcome of pancreatic cancer by Nicolle, Rémy, Blum, Yuna, Duconseil, Pauline, Vanbrugghe, Charles, Brandone, Nicolas, Poizat, Flora, Roques, Julie, Bigonnet, Martin, Gayet, Odile, Rubis, Marion, Elarouci, Nabila, Armenoult, Lucile, Ayadi, Mira, de Reyniès, Aurélien, Giovannini, Marc, Grandval, Philippe, Garcia, Stephane, Canivet, Cindy, Cros, Jérôme, Bournet, Barbara, Buscail, Louis, Moutardier, Vincent, Gilabert, Marine, Iovanna, Juan, Dusetti, Nelson

“…A significant gap in pancreatic ductal adenocarcinoma (PDAC) patient's care is the lack of molecular parameters characterizing tumours and allowing a…”
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A glycosyltransferase gene signature to detect pancreatic ductal adenocarcinoma patients with poor prognosis by Mohamed Abd-El-Halim, Yousra, El Kaoutari, Abdessamad, Silvy, Françoise, Rubis, Marion, Bigonnet, Martin, Roques, Julie, Cros, Jérôme, Nicolle, Rémy, Iovanna, Juan, Dusetti, Nelson, Mas, Eric

“…Pancreatic ductal adenocarcinoma (PDAC) is characterized by an important heterogeneity, reflected by different clinical outcomes and chemoresistance. During…”
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Sonic hedgehog and Gli1 expression predict outcome in resected pancreatic adenocarcinoma by Maréchal, Raphaël, Bachet, Jean-Baptiste, Calomme, Annabelle, Demetter, Pieter, Delpero, Jean Robert, Svrcek, Magali, Cros, Jérôme, Bardier-Dupas, Armelle, Puleo, Francesco, Monges, Geneviève, Hammel, Pascal, Louvet, Christophe, Paye, François, Bachelier, Philippe, Le Treut, Yves Patrice, Vaillant, Jean-Christophe, Sauvanet, Alain, André, Thierry, Salmon, Isabelle, Devière, Jacques, Emile, Jean-François, Van Laethem, Jean-Luc

“…Aberrant activation of the hedgehog (Hh) pathway is implicated in pancreatic ductal adenocarcinoma (PDAC) tumorigenesis. We investigated the prognostic and…”
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Pectoral I Block Does Not Improve Postoperative Analgesia After Breast Cancer Surgery: A Randomized, Double-Blind, Dual-Centered Controlled Trial by Cros, Jérôme, Sengès, Patrick, Kaprelian, Suzan, Desroches, Julie, Gagnon, Caroline, Labrunie, Anaïs, Marin, Benoît, Crépin, Sabrina, Nathan, Nathalie, Beaulieu, Pierre

“…Background and ObjectivesGeneral anesthesia for breast surgery may be supplemented by using a regional anesthetic technique. We evaluated the efficacy of the…”
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Lysyl oxidase family activity promotes resistance of pancreatic ductal adenocarcinoma to chemotherapy by limiting the intratumoral anticancer drug distribution by Le Calvé, Benjamin, Griveau, Audrey, Vindrieux, David, Maréchal, Raphaël, Wiel, Clotilde, Svrcek, Magali, Gout, Johann, Azzi, Lamia, Payen, Léa, Cros, Jérôme, de la Fouchardière, Christelle, Dubus, Pierre, Guitton, Jérôme, Bartholin, Laurent, Bachet, Jean-Baptiste, Bernard, David

“…Solid tumors often display chemotherapy resistance. Pancreatic ductal adenocarcinoma (PDAC) is the archetype of resistant tumors as current chemotherapies are…”
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DECONbench: a benchmarking platform dedicated to deconvolution methods for tumor heterogeneity quantification by Decamps, Clémentine, Arnaud, Alexis, Petitprez, Florent, Ayadi, Mira, Baurès, Aurélia, Armenoult, Lucile, Alcala, N., Arnaud, A., Avila Cobos, F., Batista, Luciana, Batto, A.-F., Blum, Y., Chuffart, F., Cros, J., Decamps, C., Dirian, L., Doncevic, D., Durif, G., Bahena Hernandez, S. Y., Jakobi, M., Jardillier, R., Jeanmougin, M., Jedynak, P., Jumentier, B., Kakoichankava, A., Kondili, Maria, Liu, J., Maie, T., Marécaille, J., Merlevede, J., Meylan, M., Nazarov, P., Newar, K., Nyrén, K., Petitprez, F., Novella Rausell, C., Richard, M., Scherer, M., Sompairac, N., Waury, K., Xie, T., Zacharouli, M.-A., Escalera, Sergio, Guyon, Isabelle, Nicolle, Rémy, Tomasini, Richard, de Reyniès, Aurélien, Cros, Jérôme, Blum, Yuna, Richard, Magali

“…Background Quantification of tumor heterogeneity is essential to better understand cancer progression and to adapt therapeutic treatments to patient…”
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Ampullary tumors: French Intergroup Clinical Practice Guidelines for diagnosis, treatments and follow-up (TNCD, SNFGE, FFCD, UNICANCER, GERCOR, SFCD, SFED, ACHBT, AFC, SFRO, RENAPE, SNFCP, AFEF, SFP, SFR) by Hautefeuille, Vincent, Williet, Nicolas, Turpin, Anthony, Napoleon, Bertrand, Dupré, Aurélien, Huguet, Florence, Bignon, Anne Laure, Camus, Marine, Chevaux, Jean-Baptiste, Coriat, Romain, Cros, Jérôme, Edeline, Julien, Koch, Stéphane, Neuzillet, Cindy, Perkins, Géraldine, Regimbeau, Jean Marc, Sefrioui, David, Vitellius, Carole, Vullierme, Marie-Pierre, Bouché, Olivier, Gaujoux, Sébastien

“…Management of ampullary tumors (AT) is challenging because of a low level of scientific evidence. This document is a summary of the French intergroup…”
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Clearance of pathogenic erythrocytes is maintained despite spleen dysfunction in children with sickle cell disease by Sissoko, Abdoulaye, Cissé, Astan, Duverdier, Clémence, Marin, Mickaël, Dumas, Lucie, Manceau, Sandra, Maître, Blandine, Eckly, Anita, Fricot‐Monsinjon, Aurélie, Roussel, Camille, Ndour, Papa Alioune, Dussiot, Michael, Dokmak, Safi, Aussilhou, Béatrice, Dembinski, Jeanne, Sauvanet, Alain, Paye, François, Lesurtel, Mickaël, Cros, Jérôme, Wendum, Dominique, Tichit, Magali, Hardy, David, Capito, Carmen, Allali, Slimane, Buffet, Pierre

“…In children with sickle cell disease (SCD), splenectomy is immediately beneficial for acute sequestration crises and hypersplenism (ASSC/HyS) but portends a…”
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Treatment outcomes of advanced digestive well-differentiated grade 3 NETs by de Mestier, Louis, Lamarca, Angela, Hernando, Jorge, Zandee, Wouter, Alonso-Gordoa, Teresa, Perrier, Marine, Walenkamp, Annemiek ME, Chakrabarty, Bipasha, Landolfi, Stefania, Van Velthuysen, Marie-Louise F, Kats-Ugurlu, Gursah, Caminoa, Alejandra, Ronot, Maxime, Manoharan, Prakash, Garcia-Alvarez, Alejandro, Brabander, Tessa, García Gómez-Muriel, María Isabel, Cadiot, Guillaume, Couvelard, Anne, Capdevila, Jaume, Pavel, Marianne E, Cros, Jérôme

“…There is no standardized treatment for grade 3 neuroendocrine tumors (G3 NETs). We aimed to describe the treatments received in patients with advanced G3 NETs…”
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Comparison between Space Mapping and Direct FEA Optimizations for the Design of Halbach Array PM Motor by Pérez, Ramón, Pelletier, Alexandre, Grenier, Jean-Michel, Cros, Jérôme, Rancourt, David, Freer, Richard

“…Effective methods for the design of high-performance electrical machines must use optimization techniques and precise and fast physical models. Convergence,…”
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Ovarian metastases of pancreatic adenocarcinoma: clinical presentation, role of surgery, and potential value of the mutational profile for the differential diagnosis with primary mucinous ovarian carcinoma by de Malet, Alice, Svrcek, Magali, Kerbaol, Anne, Theou-Anton, Nathalie, Granier, Sandra, Dokmak, Safi, Paye, François, André, Thierry, de Mestier, Louis, Cros, Jérôme, Hammel, Pascal

“…Background: Ovarian metastases (OM) of pancreatic adenocarcinoma (PA) (OM-PA) can mimic primary ovarian mucinous carcinoma (POMC) on imaging and histology…”
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S100A2 is a predictive biomarker of adjuvant therapy benefit in pancreatic adenocarcinoma by Bachet, Jean-Baptiste, Maréchal, Raphael, Demetter, Pieter, Bonnetain, Franck, Cros, Jérôme, Svrcek, Magali, Bardier-Dupas, Armelle, Hammel, Pascal, Sauvanet, Alain, Louvet, Christophe, Paye, François, Vaillant, Jean-Christophe, André, Thierry, Closset, Jean, Salmon, Isabelle, Emile, Jean-François, Van Laethem, Jean-Luc

“…Abstract Background Prognosis of patients with pancreatic adenocarcinoma (PAC) remains poor. S100A2 has been recently suggested as a negative prognostic…”
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Guidelines on human factors in critical situations 2023 by Bijok, Benjamin, Jaulin, François, Picard, Julien, Michelet, Daphné, Fuzier, Régis, Arzalier-Daret, Ségolène, Basquin, Cédric, Blanié, Antonia, Chauveau, Lucille, Cros, Jérôme, Delmas, Véronique, Dupanloup, Danièle, Gauss, Tobias, Hamada, Sophie, Le Guen, Yann, Lopes, Thomas, Robinson, Nathalie, Vacher, Anthony, Valot, Claude, Pasquier, Pierre, Blet, Alice

“…To provide guidelines to define the place of human factors in the management of critical situations in anaesthesia and critical care. A committee of nineteen…”
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