Search Results - "CRON, Greg O"
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Influence of metabolic syndrome on cerebral perfusion and cognition
Published in Neurobiology of disease (01-04-2020)“…Vascular cognitive impairment (VCI) is associated with chronic cerebral hypoperfusion (CCH) and memory deficits, and often occurs concurrently with metabolic…”
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Distinct local and brain-wide networks are activated by optogenetic stimulation of neurons specific to each layer of motor cortex
Published in NeuroImage (Orlando, Fla.) (01-11-2022)“…Primary motor cortex (M1) consists of a stack of interconnected but distinct layers (L1-L6) which affect motor control through large-scale networks. However,…”
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The SIRT1 deacetylase protects mice against the symptoms of metabolic syndrome
Published in The FASEB journal (01-03-2014)“…Type 2 diabetes, hepatic steatosis, and gut dysbiosis are pathophysiological consequences of obesity. Sirtuin (SIRT)‐1 is a protein deacetylase implicated in…”
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Imaging of the rabbit supraspinatus enthesis at 7 Tesla: a 4‐week time course after repair surgery and effect of channeling
Published in Journal of magnetic resonance imaging (01-08-2017)“…Purpose To image the supraspinatus enthesis reformation of rabbit shoulders by magnetic resonance at 7 Tesla (T) using T2 mapping after surgical repair and to…”
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Differentiation of Lipoma From Liposarcoma on MRI Using Texture and Shape Analysis
Published in Academic radiology (01-09-2014)“…Rationale and Objectives To determine if differentiation of lipoma from liposarcoma on magnetic resonance imaging can be improved using computer-assisted…”
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Fibrinogen aptamer functionalized gold-coated iron-oxide nanoparticles for targeted imaging of thrombi
Published in Chemical communications (Cambridge, England) (24-02-2022)“…Targeting of molecular constituents of thrombi with aptamer functionalized core-shell nanoparticles (CSN) allowed for high resolution clot delineation in…”
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Botulinum toxin potentiates cancer radiotherapy and chemotherapy
Published in Clinical cancer research (15-02-2006)“…PURPOSE: Structural and functional abnormalities in the tumor vascular network are considered factors of resistance of solid tumors to cytotoxic treatments. To…”
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Repeated hippocampal seizures lead to brain-wide reorganization of circuits and seizure propagation pathways
Published in Neuron (Cambridge, Mass.) (19-01-2022)“…Repeated seizure activity can lead to long-term changes in seizure dynamics and behavior. However, resulting changes in brain-wide dynamics remain poorly…”
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Exploring the Unique Contrast Properties of Aptamer–Gadolinium Conjugates in Magnetic Resonance Imaging for Targeted Imaging of Thrombi
Published in ACS applied materials & interfaces (03-03-2021)“…Objective: An important clinical question in the determination of the extent of thrombosis-related vascular conditions is the identification of blood clot…”
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Prospective comparative diagnostic accuracy evaluation of dynamic contrast‐enhanced (DCE) vs. dynamic susceptibility contrast (DSC) MR perfusion in differentiating tumor recurrence from radiation necrosis in treated high‐grade gliomas
Published in Journal of magnetic resonance imaging (01-08-2019)“…Background The appearance of a new enhancing lesion after surgery and chemoradiation for high‐grade glioma (HGG) presents a common diagnostic dilemma…”
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Lateral Trochlear Ridge: A Non-Articulating Zone for Anterior-to-Posterior Screw Placement in Fractures Involving the Capitellum and Trochlea
Published in Journal of bone and joint surgery. American volume (07-08-2019)“…Coronal shear fractures of the distal aspect of the humerus that involve the capitellum and the trochlea are rare; nevertheless, they are difficult to treat…”
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Methylenetetrahydrofolate reductase deficiency alters cellular response after ischemic stroke in male mice
Published in Nutritional neuroscience (04-03-2022)“…Objective: Elevated homocysteine concentrations are a risk factor for stroke. A common genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR 677…”
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Co-targeting Bulk Tumor and CSCs in Clinically Translatable TNBC Patient-Derived Xenografts via Combination Nanotherapy
Published in Molecular cancer therapeutics (01-10-2019)“…Triple-negative breast cancer (TNBC) accounts disproportionally for the majority of breast cancer-related deaths throughout the world. This is largely…”
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Intracranial Displacement Measurements Within Targeted Anatomical Regions of a Postmortem Human Surrogate Brain Subjected to Impact
Published in Annals of biomedical engineering (01-10-2021)“…The dynamic response of the human brain subjected to impulsive loading conditions is of fundamental importance to the understanding of traumatic brain…”
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Holocranohistochemistry enables the visualization of α-synuclein expression in the murine olfactory system and discovery of its systemic anti-microbial effects
Published in Journal of Neural Transmission (01-06-2017)“…Braak and Del Tredici have proposed that typical Parkinson disease (PD) has its origins in the olfactory bulb and gastrointestinal tract. However, the role of…”
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19F NMR in vivo spectroscopy reflects the effectiveness of perfusion-enhancing vascular modifiers for improving gemcitabine chemotherapy
Published in Magnetic resonance in medicine (01-01-2008)“…Nuclear magnetic resonance spectroscopy of fluorine‐19 (19F NMR) has proven useful for evaluating kinetics of fluorinated chemotherapy drugs in tumors in vivo…”
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Imaging cognitive fatigability in multiple sclerosis: objective quantification of cerebral blood flow during a task of sustained attention using ASL perfusion fMRI
Published in Brain imaging and behavior (01-12-2020)“…Cognitive fatigability (CF) can be defined as an inability to maintain performance throughout a sustained cognitive task. Individuals with multiple sclerosis…”
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NK-Cell Recruitment Is Necessary for Eradication of Peritoneal Carcinomatosis with an IL12-Expressing Maraba Virus Cellular Vaccine
Published in Cancer immunology research (01-03-2017)“…Despite improvements in chemotherapy and radical surgical debulking, peritoneal carcinomatosis (PC) remains among the most common causes of death from…”
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PET imaging of a collagen matrix reveals its effective injection and targeted retention in a mouse model of myocardial infarction
Published in Biomaterials (01-05-2015)“…Abstract Injectable biomaterials have shown promise for cardiac regeneration therapy. However, little is known regarding their retention and distribution upon…”
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