Search Results - "CRIST, K. A"

5-Aza-2'-deoxycytidine is chemopreventive in a 4-(methyl-nitrosamino)-1-(3-pyridyl)-1-butanone-induced primary mouse lung tumor model by LANTRY, L. E, ZHANG, Z, CRIST, K. A, WANG, Y, KELLOFF, G. J, LUBET, R. A, YOU, M

“…Carcinogenesis is a multistep process in which many alterations in both genetic and epigenetic controls lead to a growth advantage for neoplastic cells…”
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Effect of farnesyltransferase inhibitor FTI-276 on established lung adenomas from A/J mice induced by 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by Lantry, Laura E., Zhang, Zhongqiu, Yao, Rusheng, Crist, Keith A., Wang, Yian, Ohkanda, Junko, Hamilton, Andrew D., Sebti, Said M., lubet, Ronald A., You, Ming

“…The Ras protein undergoes a series of post-translational modifications at the C-terminal CAAX motif, which culminates with the anchoring of p21 Ras to the…”
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Distribution of estrogen receptor in ductal carcinoma in situ of the breast by Chaudhuri, B, Crist, K A, Mucci, S, Malafa, M, Chaudhuri, P K

“…Long-term antiestrogen therapy has been suggested as a possible treatment alternative for ductal carcinoma in situ (DCIS) of the breast. However, very little…”
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Pharmacokinetics and toxicity of isolated perfusion of lung with doxorubicin by Baciewicz, Jr, F A, Arredondo, M, Chaudhuri, B, Crist, K A, Basilius, D, Bandyopadhyah, S, Thomford, N R, Chaudhuri, P K

“…The treatment of pulmonary metastases from soft tissue sarcomas with chemotherapy has an overall response rate of less than 30%, and the majority of these…”
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Effects of culture duration on hydrogen peroxide-induced hepatocyte toxicity by Ruch, R J, Crist, K A, Klaunig, J E

“…The effects of culture duration on primary cultured mouse hepatocyte antioxidant levels (superoxide dismutase, catalase, glutathione peroxidase, vitamin E, and…”
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Effect of CCK receptor antagonist on growth of pancreatic adenocarcinoma by Shivaram, S, Crist, K A, Chaudhuri, B, Mucci, S J, Chaudhuri, P K

“…Cholecystokinin (CCK) exerts an influential effect on the growth of normal pancreas. It is postulated that carcinoma arising from the pancreas may retain some…”
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CHEMOPREVENTIVE EFFICACY OF PROMISING FARNESYLTRANSFERASE INHIBITORS by Lantry, Laura E., Zhang, Zhongqiu, Crist, Keith A., Wang, Yian, Hara, Mitsunobu, Zeeck, Axel, Lubet, Ronald A., You, Ming

“…The studies presented were designed to test the efficacy of farnesyltransferase inhibitors (FTIs) as potential chemopreventive compounds in the mouse lung…”
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Temporal adjustments in sympathoadrenal activity in rats with obesity-producing hypothalamic knife cuts by Vander Tuig, J G, Crist, K A, Romsos, D R

“…Sympathoadrenal activity was assessed in adult rats with obesity-producing hypothalamic knife cuts prior to and after the onset of gross obesity by measuring…”
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Altered gene expression profile in chemically induced rat mammary adenocarcinomas and its modulation by an aromatase inhibitor by YIAN WANG, LAN HU, RUISHENG YAO, MIN WANG, CRIST, Keith A, GRUBBS, Clinton J, JOHANNING, Gary L, LUBET, Ronald A, MING YOU

“…In the present study, competitive cDNA library screening (CCLS) and cDNA microarray analyses were employed to identify differentially expressed genes in…”
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Evidence for cold-induced but not for diet-induced thermogenesis in adult dogs by Crist, K A, Romsos, D R

“…Rats often exhibit diet-induced thermogenesis when overfed, which has been linked to activation of the sympathetic nervous system. In the present study, adult…”
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Palmitate and stearate kinetics in the rat during sepsis and trauma by Cardwell, R J, Birkhahn, R H, Crist, K A, Lee, E M, Thomford, N R

“…Kinetics of plasma free palmitate and stearate were measured in control and septic-traumatized rats to determine the contribution plasma free fatty acids make…”
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Additional Evidence That the K-ras Protooncogene is a Candidate for the Major Mouse Pulmonary Adenoma Susceptibility (Pas-1) Gene by Lin, Lin, Festing, Michael F. W., Devereux, Theodora R., Crist, Keith A., Christiansen, Steven C., Wang, Yian, Yang, Alice, Svenson, Karen, Paigen, Beverly, Malkinson, Alvin M., You, Ming

“…A locus for mouse pulmonary adenoma susceptibility, Pas-1, has been mapped on distal chromosome 6, where the K-ras gene is located. Allele-specific activation…”
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Chromosome 3p tumor-suppressor gene alterations in cervical carcinomas by Herzog, Christopher R., Crist, Keith A., Sabourin, Carol L. K., Kelloff, Gary J., Boone, Charles W., Stoner, Gary D., You, Ming

“…Loss of heterozygosity (LOH) on chromosome 3p is a common event in cervical cancer and typically occurs in a dispersed pattern involving several loci. This…”
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Effect of green tea on p53 mutation distribution in ultraviolet B radiation-induced mouse skin tumors by QING LIU, YUE WANG, A.CRIST, K, WANG, Z.-Y, LOU, Y.-R, HUANG, M.-T, CONNEY, A. H, MING YOU

“…In the present study, administration of green tea to SKH-1 mice, via the drinking fluid, was found to significantly reduce the incidence and volume of…”
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Gemcitabine enhances the sensitivity of renal cell cancer to cytolysis by IL2-activated lymphocytes by Braun, D. P., Kloesel, B., Crist, K. A.

“…Abstract only…”
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Detection of differentially expressed genes in Methylnitrosourea-induced rat mammary adenocarcinomas by Hu, Lan, Lin, Lin, Crist, Keith A., Kelloff, Gary J., Steele, Vernon E., Lubet, Ronald A., You, Ming, Wang, Yian

“…In this study, altered gene expression in five methylnitrosourea (MNU)‐induced rat mammary adenocarcinomas was investigated using a newly developed competitive…”
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Effect of early vs. late administration of 4-Hydroxyphenylretinamide (4-HPR) on N-Methyl-N-Nitrosourea (MNU)-induced mammary tumorigenesis by Crist, Keith A., Wang, Yian, Lubet, Ronald A., Steele, Vernon E., Kelloff, Gary J., You, Ming

“…Mammary tumors were induced in 48–52‐day‐old female Sprague‐Dawley rats in metestrus or diestrus with a single jugular injection of MNU (50 mg/kg). Control…”
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Estrogen receptor in carcinoma in situ of the cervix by Chaudhuri, B, Crist, K A, Mucci, S J, Thomford, N R, Chaudhuri, P K

“…The lining epithelium of the human cervix uteri is an estrogen dependent tissue containing specific intracellular receptors for this hormone. However, the…”
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The pattern of injury to rear seat passengers involved in automobile collisions by Mucci, S J, Eriksen, L D, Crist, K A, Bernath, L A, Chaudhuri, P K

“…This retrospective study analyzed the pattern of injury among rear seat occupants in automobile collisions and compared the incidence and type of injury with…”
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Palmitic acid kinetics in fasting, traumatized patients by Birkhahn, R H, Cardwell, R J, Birkhahn, G C, Crist, K A, Taha, A M, Thomford, N R

“…The contribution of free fatty acid oxidation to the elevation in energy expenditure after trauma has not been well characterized. Six control subjects and six…”
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