Search Results - "CRIPPA, Alexandre"
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Neuropharmacological Effects of the Main Phytocannabinoids: A Narrative Review
Published in Advances in experimental medicine and biology (01-01-2021)“…Cannabis can synthetize more than 400 compounds, including terpenes, flavonoids, and more than 100 phytocannabinoids. The main phytocannabinoids are…”
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The psychedelic state induced by ayahuasca modulates the activity and connectivity of the default mode network
Published in PloS one (18-02-2015)“…The experiences induced by psychedelics share a wide variety of subjective features, related to the complex changes in perception and cognition induced by this…”
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Antidepressant Effects of a Single Dose of Ayahuasca in Patients With Recurrent Depression: A SPECT Study
Published in Journal of clinical psychopharmacology (01-02-2016)“…Ayahuasca is an Amazonian botanical hallucinogenic brew which contains dimethyltryptamine, a 5-HT2A receptor agonist, and harmine, a monoamine-oxidase A…”
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Safety and side effects of cannabidiol, a Cannabis sativa constituent
Published in Current drug safety (01-09-2011)“…Cannabidiol (CBD), a major nonpsychotropic constituent of Cannabis, has multiple pharmacological actions, including anxiolytic, antipsychotic, antiemetic and…”
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Effects of cannabidiol in the treatment of patients with Parkinson’s disease: An exploratory double-blind trial
Published in Journal of psychopharmacology (Oxford) (01-11-2014)“…Introduction: Parkinson’s disease (PD) has a progressive course and is characterized by the degeneration of dopaminergic neurons. Although no neuroprotective…”
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Fifty years of research on cannabidiol (CBD) as an anticonvulsant: The legacy of Brazilian groups
Published in Revista brasileira de psiquiatria (01-11-2023)Get full text
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Effects of cannabidiol on symptoms induced by the recall of traumatic events in patients with posttraumatic stress disorder
Published in Psychopharmacology (01-05-2022)“…Studies with cannabidiol (CBD) suggest that this compound has anxiolytic properties and may mediate the reconsolidation and extinction of aversive memories…”
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Effects of acute cannabidiol administration on anxiety and tremors induced by a Simulated Public Speaking Test in patients with Parkinson’s disease
Published in Journal of psychopharmacology (Oxford) (01-02-2020)“…Background: Cannabidiol (CBD) is one of the main components of Cannabis sativa and has anxiolytic properties, but no study has been conducted to evaluate the…”
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Cannabidiol Reduces the Anxiety Induced by Simulated Public Speaking in Treatment-Naïve Social Phobia Patients
Published in Neuropsychopharmacology (New York, N.Y.) (01-05-2011)“…Generalized Social Anxiety Disorder (SAD) is one of the most common anxiety conditions with impairment in social life. Cannabidiol (CBD), one major…”
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A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation
Published in Current pharmaceutical design (01-11-2012)“…Δ(9)-tetrahydrocannabinol (Δ(9)-THC) is the main compound of the Cannabis Sativa responsible for most of the effects of the plant. Another major constituent is…”
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Cannabidiol attenuates mechanical allodynia in streptozotocin-induced diabetic rats via serotonergic system activation through 5-HT1A receptors
Published in Brain research (15-07-2019)“…•Cannabidiol exerts significant anti-allodynic effect in diabetic neuropathic pain.•Cannabidiol does not alter locomotor activity in diabetic animals.•5-HT1A…”
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Classical hallucinogens and neuroimaging: A systematic review of human studies: Hallucinogens and neuroimaging
Published in Neuroscience and biobehavioral reviews (01-12-2016)“…Serotonergic hallucinogens produce alterations of perceptions, mood, and cognition, and have anxiolytic, antidepressant, and antiaddictive properties. These…”
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Neuroimaging in social anxiety disorder: A systematic review of the literature
Published in Progress in neuro-psychopharmacology & biological psychiatry (30-05-2010)“…Brain imaging techniques allow the in vivo evaluation of the human brain, leading to a better understanding of its anatomical, functional and metabolic…”
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Recent advances in LC-MS/MS methods to determine endocannabinoids in biological samples: Application in neurodegenerative diseases
Published in Analytica chimica acta (31-12-2018)“…Endocannabinoids (ECs) are endogenous lipid-based retrograde neurotransmitters that bind to cannabinoid receptors [cannabinoid receptor 1 (CB1) and cannabinoid…”
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Neural basis of anxiolytic effects of cannabidiol (CBD) in generalized social anxiety disorder: a preliminary report
Published in Journal of psychopharmacology (Oxford) (01-01-2011)“…Animal and human studies indicate that cannabidiol (CBD), a major constituent of cannabis, has anxiolytic properties. However, no study to date has…”
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Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years
Published in Therapeutic Advances in Psychopharmacology (01-06-2016)“…To date, pharmacological treatments for mood and anxiety disorders and for drug dependence show limited efficacy, leaving a large number of patients suffering…”
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Altered gray matter morphometry and resting-state functional and structural connectivity in social anxiety disorder
Published in Brain research (04-05-2011)“…Abstract In social anxiety disorder (SAD), impairments in limbic/paralimbic structures are associated with emotional dysregulation and inhibition of the medial…”
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Long-term use of psychedelic drugs is associated with differences in brain structure and personality in humans
Published in European neuropsychopharmacology (01-04-2015)“…Abstract Psychedelic agents have a long history of use by humans for their capacity to induce profound modifications in perception, emotion and cognitive…”
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Assessing the Psychedelic “After-Glow” in Ayahuasca Users: Post-Acute Neurometabolic and Functional Connectivity Changes Are Associated with Enhanced Mindfulness Capacities
Published in The international journal of neuropsychopharmacology (01-09-2017)“…Abstract Background Ayahuasca is a plant tea containing the psychedelic 5-HT2A agonist N,N-dimethyltryptamine and harmala monoamine-oxidase inhibitors. Acute…”
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Cannabis and anxiety: a critical review of the evidence
Published in Human psychopharmacology (01-10-2009)“…Background Anxiety reactions and panic attacks are the acute symptoms most frequently associated with cannabis use. Understanding the relationship between…”
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