Search Results - "CRIPE, Larry D"
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Extramedullary Disease in Adult Acute Myeloid Leukemia Is Common but Lacks Independent Significance: Analysis of Patients in ECOG-ACRIN Cancer Research Group Trials, 1980-2008
Published in Journal of clinical oncology (10-10-2016)“…Purpose Extramedullary disease (EMD) at diagnosis in patients with acute myeloid leukemia (AML) has been recognized for decades. Reported herein are results…”
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Very poor long‐term survival in past and more recent studies for relapsed AML patients: The ECOG‐ACRIN experience
Published in American journal of hematology (01-08-2018)“…This study examines the long‐term OS of relapsed AML patients who were enrolled to 9 successive ECOG‐ACRIN trials for newly diagnosed AML, during 1984‐2008…”
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Music Therapy Is Associated With Family Perception of More Spiritual Support and Decreased Breathing Problems in Cancer Patients Receiving Hospice Care
Published in Journal of pain and symptom management (01-08-2015)“…Abstract Context Music therapy is a common discretionary service offered within hospice; however, there are critical gaps in understanding the effects of music…”
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Targeted detection and quantitation of histone modifications from 1,000 cells
Published in PloS one (26-10-2020)“…Histone post-translational modifications (PTMs) create a powerful regulatory mechanism for maintaining chromosomal integrity in cells. Histone acetylation and…”
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Independent Prognostic Significance of Monosomy 17 and Impact of Karyotype Complexity in Monosomal Karyotype/Complex Karyotype Acute Myeloid Leukemia: Results from Four ECOG-ACRIN Prospective Therapeutic Trials
Published in Leukemia research (01-08-2017)“…Highlights • Prognostic impact of monosomal karyotype appears dependent on karyotype complexity. • Monosomy 5 lacks prognostic impact in context of AML with…”
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A phase 1b/2 study of vosaroxin in combination with cytarabine in patients with relapsed or refractory acute myeloid leukemia
Published in Haematologica (Roma) (01-02-2015)“…Vosaroxin is a first-in-class anticancer quinolone derivative that intercalates DNA and inhibits topoisomerase II. This study assessed the safety and…”
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Cell signaling-based classifier predicts response to induction therapy in elderly patients with acute myeloid leukemia
Published in PloS one (17-04-2015)“…Single-cell network profiling (SCNP) data generated from multi-parametric flow cytometry analysis of bone marrow (BM) and peripheral blood (PB) samples…”
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Predicting symptoms of anxiety and depression in patients living with advanced cancer: the differential roles of hope and optimism
Published in Supportive care in cancer (01-10-2018)“…Purpose Psychological distress is related to poorer functioning and reduced quality of life in patients with advanced cancer and may have untoward influences…”
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Hope Is the Thing With Feathers
Published in JAMA : the journal of the American Medical Association (19-01-2016)“…Cripe talks about the capacity to hope. Hopefulness is a fundamental human perspective that allows a person to imagine the future as possible and, to some…”
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Inhibition of Syk with fostamatinib disodium has significant clinical activity in non-Hodgkin lymphoma and chronic lymphocytic leukemia
Published in Blood (01-04-2010)“…Certain malignant B cells rely on B-cell receptor (BCR)–mediated survival signals. Spleen tyrosine kinase (Syk) initiates and amplifies the BCR signal. In in…”
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Results from a randomized trial of salvage chemotherapy followed by lestaurtinib for patients with FLT3 mutant AML in first relapse
Published in Blood (24-03-2011)“…In a randomized trial of therapy for FMS-like tyrosine kinase-3 (FLT3) mutant acute myeloid leukemia in first relapse, 224 patients received chemotherapy alone…”
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Goals of care communication and higher-value care for patients with advanced-stage cancer: A systematic review of the evidence
Published in Patient education and counseling (01-05-2022)“…•We couldn’t derive a consensus definition of GOC communication topics, behaviors, timing, or anticipated outcomes.•Goals were most commonly descriptions of…”
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We were in the fight together: The expectations of bereaved caregivers of patients with acute myeloid leukemia from diagnosis to death
Published in Leukemia research (01-01-2023)“…Patients with hematologic malignancies are more optimistic than their oncologists and their expectations may be a barrier to timely hospice care. Patient…”
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Zosuquidar, a novel modulator of P-glycoprotein, does not improve the outcome of older patients with newly diagnosed acute myeloid leukemia: a randomized, placebo-controlled trial of the Eastern Cooperative Oncology Group 3999
Published in Blood (18-11-2010)“…Zosuquidar, which modulates P-glycoprotein (P-gp) with minimal delay of anthracycline clearance, may reverse P-gp–mediated resistance in acute myeloid leukemia…”
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The Goal Inventory: An Innovative Digital Resource to Help Patients Identify and Evaluate Their Goals
Published in Journal of pain and symptom management (01-10-2024)Get full text
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Obesity in adult acute myeloid leukemia is not associated with inferior response or survival even when dose capping anthracyclines: An ECOG‐ACRIN analysis
Published in Cancer (15-08-2023)“…Background Obesity (body mass index [BMI] ≥30 kg/m2) is an important epidemiological risk factor for developing acute myeloid leukemia (AML). Therefore, the…”
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Life and treatment goals of patients with advanced, incurable cancer
Published in Supportive care in cancer (01-07-2016)“…Purpose Goals of care conversations have been suggested as a strategy for helping patients with advanced cancer manage the uncertainty and distress associated…”
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Prognostic effect of gender on outcome of treatment for adults with acute myeloid leukaemia
Published in British journal of haematology (01-07-2021)“…Summary There are conflicting reports in the literature suggesting that one gender or the other has a better survival with acute myeloid leukaemia (AML). The…”
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