Search Results - "CRIDER, J. Y"

Ocular hypotensive FP prostaglandin (PG) analogs: PG receptor subtype binding affinities and selectivities, and agonist potencies at FP and other PG receptors in cultured cells by Sharif, N A, Kelly, C R, Crider, J Y, Williams, G W, Xu, S X

“…Natural prostaglandins (PGs) such as PGD2, PGE2, PGF2(2alpha), and PGI2 exhibited the highest affinity for their respective cognate receptors, but were the…”
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Prostaglandin DP receptors positively coupled to adenylyl cyclase in embryonic bovine tracheal (EBTr) cells: pharmacological characterization using agonists and antagonists by Crider, J Y, Griffin, B W, Sharif, N A

“…Various prostaglandin agonists representing various classes of receptor subtypes were evaluated for their ability to stimulate adenylyl cyclase via the…”
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FP prostaglandin receptors mediating inositol phosphates generation and calcium mobilization in Swiss 3T3 cells: a pharmacological study by Griffin, B W, Williams, G W, Crider, J Y, Sharif, N A

“…A detailed pharmacological characterization of the prostaglandin (PG) receptor coupled to phosphoinositide (PI) turnover and intracellular calcium mobilization…”
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Agonist activity of bimatoprost, travoprost, latanoprost, unoprostone isopropyl ester and other prostaglandin analogs at the cloned human ciliary body FP prostaglandin receptor by Sharif, N A, Kelly, C R, Crider, J Y

“…We have determined the agonist activity of a number of natural prostaglandins and prostaglandin analogs at the FP prostaglandin receptor cloned from a human…”
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Levobetaxolol (Betaxon) and other beta-adrenergic antagonists: preclinical pharmacology, IOP-lowering activity and sites of action in human eyes by Sharif, N A, Xu, S X, Crider, J Y, McLaughlin, M, Davis, T L

“…The pharmacological characteristics of levobetaxolol, a single active isomer of betaxolol, were determined and compared with activities of other…”
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Endogenous EP4 prostaglandin receptors coupled positively to adenylyl cyclase in Chinese hamster ovary cells : pharmacological characterization by CRIDER, J. Y, GRIFFIN, B. W, SHARIF, N. A

“…The purpose of these studies was to investigate the pharmacology of E-series and selected prostaglandins of other classes on adenylyl cyclase activity in…”
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AL-3138 Antagonizes FP Prostanoid Receptor-mediated Inositol Phosphates Generation: Comparison with Some Purported FP Antagonists by SHARIF, N. A., CRIDER, J. Y., DAVIS, T. L.

“…The aim of this study was to pharmacologically characterize the antagonist properties of a novel prostaglandin F2α (PGF2α) analogue (11‐deoxy‐16‐fluoro PGF2α;…”
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Pharmacology of functional endogenous IP prostanoid receptors in NCB-20 cells: comparison with binding data from human platelets by Crider, J.Y., Xu, S.X., Sharif, N.A.

“…The objective of these studies was to characterize the effects of a broad range of prostanoid agonists upon the stimulation of cAMP production in National…”
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Use of a semi-automated, robotic radioimmunoassay to measure cAMP generated by activation of DP-, EP2-, and IP-prostaglandin receptors in human ocular and other cell types by CRIDER, J. Y, GRIFFIN, B. W, XU, S. X, SHARIF, N. A

“…The aim of these studies was to compare the effects of several prostaglandin agonists on adenylyl cyclase activity in embryonic bovine tracheal (EBTr) cells,…”
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Prostaglandin-stimulated adenylyl cyclase activity via a pharmacologically defined EP2 receptor in human nonpigmented ciliary epithelial cells by Crider, J Y, Griffin, B W, Sharif, N A

“…The goal of these studies was to compare the effects of several prostaglandin (PG) receptor agonists on adenylyl cyclase activity in transformed human…”
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Pharmacological analysis of mast cell mediator and neurotransmitter receptors coupled to adenylate cyclase and phospholipase C on immunocytochemically-defined human conjunctival epithelial cells by Sharif, N A, Crider, J Y, Griffin, B W, Davis, T L, Howe, W E

“…We sought to establish and immunocytochemically characterize primary cultures of human conjunctival epithelial (HCE) cells, and to determine the types of…”
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The effects of elevated glucose on Na+/K(+)-ATPase of cultured bovine retinal pigment epithelial cells measured by a new nonradioactive rubidium uptake assay by Crider, J Y, Yorio, T, Sharif, N A, Griffin, B W

“…The effects of stimulated hyperglycemia on the Na+/K(+)-ATPase activity of cultured bovine retinal pigment epithelial (RPE) cells were investigated. Total Rb+…”
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Levobetaxolol (Betaxon): in vitro pharmacology, intraocular pressure lowering activity and autoradiographic localization of beta-adrenoceptors in human eyes by Sharif, N A, Crider, J Y, Xu, S X, McLaughlin, M, Davis, T L

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Affinities, selectivities, potencies, and intrinsic activities of natural and synthetic prostanoids using endogenous receptors: focus on DP class prostanoids by Sharif, N A, Crider, J Y, Xu, S X, Williams, G W

“…The prostanoid receptor-subtype binding affinities, selectivities, potencies, and intrinsic activities of four natural prostanoids and six synthetic DP class…”
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Functional pharmacological evidence for EP2 and EP4 prostanoid receptors in immortalized human trabecular meshwork and non-pigmented ciliary epithelial cells by Crider, J Y, Sharif, N A

“…The aim of these studies was to characterize the molecular pharmacology of the prostanoid receptors positively coupled to stimulation of adenylyl cyclase…”
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A new chromatographic method for measurement of rubidium transport activities in cultured bovine retinal pigment epithelial cells by Crider, J Y, Williams, G W, Yorio, T, Sharif, N A, Griffin, B W

“…A new method for measuring cellular rubidium (Rb+) uptake activities based on cation chromatography was developed and compared with the standard technique,…”
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Human Trabecular Meshwork Cell Responses Induced by Bimatoprost, Travoprost, Unoprostone, and other FP Prostaglandin Receptor Agonist Analogues by Sharif, Najam A, Kelly, Curtis R, Crider, Julie Y

“…To determine the functional agonist potencies of the intraocular pressure (IOP)-lowering prostaglandin F (FP)-class prostaglandin (PG) analogues (e.g.,…”
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Effects of naphthalene on the hemoglobin concentration and oxygen uptake of Daphnia magna by Crider, J.Y, Wilhm, J, Harmon, H.J

“…Results are given of experiments on the effect of naphthalene, an important constituent of oil , on Daphnia magna. Significant effects on haemoglobin content…”
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AL-8810: a novel prostaglandin F2 alpha analog with selective antagonist effects at the prostaglandin F2 alpha (FP) receptor by Griffin, B W, Klimko, P, Crider, J Y, Sharif, N A

“…A novel analog of prostaglandin F(2alpha) [AL-8810; (5Z, 13E)-(9S, 11S,15R)-9,15-dihydroxy-11-fluoro-15-(2-indanyl)-16,17,18,19, 20-pentanor-5,13-prostadienoic…”
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Human ciliary muscle cell responses to FP-class prostaglandin analogs: phosphoinositide hydrolysis, intracellular Ca2+ mobilization and MAP kinase activation by Sharif, Naj A, Crider, Julie Y, Husain, Shahid, Kaddour-Djebbar, Ismail, Ansari, Habib R, Abdel-Latif, Ata A

“…Phospholipase C induced phosphoinositide (PI) turnover, intracellular Ca(2+) ([Ca(2+)](i)) mobilization and mitogen-activated protein (MAP) kinase activation…”
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