Search Results - "CRESTANI, Maurizio"

PGC1s and Beyond: Disentangling the Complex Regulation of Mitochondrial and Cellular Metabolism by Coppi, Lara, Ligorio, Simona, Mitro, Nico, Caruso, Donatella, De Fabiani, Emma, Crestani, Maurizio

“…Metabolism is the central engine of living organisms as it provides energy and building blocks for many essential components of each cell, which are required…”
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Ketogenic Diet: A New Light Shining on Old but Gold Biochemistry by Longo, Raffaella, Peri, Carolina, Cricrì, Dalma, Coppi, Lara, Caruso, Donatella, Mitro, Nico, De Fabiani, Emma, Crestani, Maurizio

“…Diets low in carbohydrates and proteins and enriched in fat stimulate the hepatic synthesis of ketone bodies (KB). These molecules are used as alternative fuel…”
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Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue by GALMOZZI, Andrea, MITRO, Nico, VALENTE, Sergio, GUERRINI, Uliano, CARUSO, Donatella, MAI, Antonello, SAEZ, Enrique, DE FABIANI, Emma, CRESTANI, Maurizio, FERRARI, Alessandra, GERS, Elise, GILARDI, Federica, GODIO, Cristina, CERMENATI, Gaia, GUALERZI, Alice, DONETTI, Elena, ROTILI, Dante

“…Chromatin modifications are sensitive to environmental and nutritional stimuli. Abnormalities in epigenetic regulation are associated with metabolic disorders…”
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Conditioning the microenvironment for soft tissue regeneration in a cell free scaffold by Gerges, Irini, Tamplenizza, Margherita, Martello, Federico, Koman, Stefano, Chincarini, Giulia, Recordati, Camilla, Tamplenizza, Mariacaterina, Guelcher, Scott, Crestani, Maurizio, Tocchio, Alessandro

“…The use of cell-free scaffolds for the regeneration of clinically relevant volumes of soft tissue has been challenged, particularly in the case of synthetic…”
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HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning by Ferrari, Alessandra, Longo, Raffaella, Fiorino, Erika, Silva, Rui, Mitro, Nico, Cermenati, Gaia, Gilardi, Federica, Desvergne, Béatrice, Andolfo, Annapaola, Magagnotti, Cinzia, Caruso, Donatella, Fabiani, Emma De, Hiebert, Scott W., Crestani, Maurizio

“…White adipose tissue (WAT) can undergo a phenotypic switch, known as browning, in response to environmental stimuli such as cold. Post-translational…”
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Does microRNA Perturbation Control the Mechanisms Linking Obesity and Diabetes? Implications for Cardiovascular Risk by La Sala, Lucia, Crestani, Maurizio, Garavelli, Silvia, de Candia, Paola, Pontiroli, Antonio E

“…Metabolic disorders such as obesity and type 2 diabetes (T2D) are considered the major risk factors for the development of cardiovascular diseases (CVD)…”
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Histone Deacetylase 3 Regulates Adipocyte Phenotype at Early Stages of Differentiation by Cricrí, Dalma, Coppi, Lara, Pedretti, Silvia, Mitro, Nico, Caruso, Donatella, De Fabiani, Emma, Crestani, Maurizio

“…Obesity is a condition characterized by uncontrolled expansion of adipose tissue mass resulting in pathological weight gain. Histone deacetylases (HDACs) have…”
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An Essential Role for Liver ERα in Coupling Hepatic Metabolism to the Reproductive Cycle by Della Torre, Sara, Mitro, Nico, Fontana, Roberta, Gomaraschi, Monica, Favari, Elda, Recordati, Camilla, Lolli, Federica, Quagliarini, Fabiana, Meda, Clara, Ohlsson, Claes, Crestani, Maurizio, Uhlenhaut, Nina Henriette, Calabresi, Laura, Maggi, Adriana

“…Lipoprotein synthesis is controlled by estrogens, but the exact mechanisms underpinning this regulation and the role of the hepatic estrogen receptor α (ERα)…”
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Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation by Cermenati, Gaia, Abbiati, Federico, Cermenati, Solei, Brioschi, Elisabetta, Volonterio, Alessandro, Cavaletti, Guido, Saez, Enrique, De Fabiani, Emma, Crestani, Maurizio, Garcia-Segura, Luis M., Melcangi, Roberto C., Caruso, Donatella, Mitro, Nico

“…Diabetic peripheral neuropathy (DPN) is characterized by myelin abnormalities; however, the molecular mechanisms underlying such deficits remain obscure. To…”
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Dietary Mannan Oligosaccharides Modulate Gut Inflammatory Response and Improve Duodenal Villi Height in Post-Weaning Piglets Improving Feed Efficiency by Agazzi, Alessandro, Perricone, Vera, Zorini, Fabio Omodei, Sandrini, Silvia, Mariani, Elena, Jiang, Xian- Ren, Ferrari, Alessandra, Crestani, Maurizio, Nguyen, Thi Xuan, Bontempo, Valentino, Domeneghini, Cinzia, Savoini, Giovanni

“…The aim of this study was to evaluate the effects of mannan oligosaccharides (MOS) on gut health and performance in post-weaning piglets. In total, 40 piglets…”
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Activation of a non-neuronal cholinergic system in visceral white adipose tissue of obese mice and humans by Severi, Ilenia, Perugini, Jessica, Ruocco, Chiara, Coppi, Lara, Pedretti, Silvia, Di Mercurio, Eleonora, Senzacqua, Martina, Ragni, Maurizio, Imperato, Gabriele, Valerio, Alessandra, Mitro, Nico, Crestani, Maurizio, Nisoli, Enzo, Giordano, Antonio

“…Since white adipose tissue (WAT) lacks parasympathetic cholinergic innervation, the source of the acetylcholine (ACh) acting on white adipocyte cholinergic…”
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The sirtuin class of histone deacetylases: Regulation and roles in lipid metabolism by Fiorino, Erika, Giudici, Marco, Ferrari, Alessandra, Mitro, Nico, Caruso, Donatella, De Fabiani, Emma, Crestani, Maurizio

“…After the completion of the human genome sequence and that from many other organisms, last decade has witnessed a spectacular gain of knowledge on gene…”
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Effects of nucleotides administration on growth performance and immune response of post-weaning piglets by Perricone, Vera, Comi, Marcello, Bontempo, Valentino, Lecchi, Cristina, Ceciliani, Fabrizio, Crestani, Maurizio, Ferrari, Alessandra, Savoini, Giovanni, Agazzi, Alessandro

“…The aim of this study was to assess the effect of nucleotides administration on growth performance and immune response in post-weaning piglets. Twenty-eight…”
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"The Loss of Golden Touch": Mitochondria-Organelle Interactions, Metabolism, and Cancer by Audano, Matteo, Pedretti, Silvia, Ligorio, Simona, Crestani, Maurizio, Caruso, Donatella, De Fabiani, Emma, Mitro, Nico

“…Mitochondria represent the energy hub of cells and their function is under the constant influence of their tethering with other subcellular organelles…”
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Neuroactive steroid treatment modulates myelin lipid profile in diabetic peripheral neuropathy by Mitro, Nico, Cermenati, Gaia, Brioschi, Elisabetta, Abbiati, Federico, Audano, Matteo, Giatti, Silvia, Crestani, Maurizio, De Fabiani, Emma, Azcoitia, Inigo, Garcia-Segura, Luis Miguel, Caruso, Donatella, Melcangi, Roberto Cosimo

“…Diabetic peripheral neuropathy causes a decrease in the levels of dihydroprogesterone and 5α-androstane-3α,17β-diol (3α-diol) in the peripheral nerves. These…”
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Coordinated Control of Cholesterol Catabolism to Bile Acids and of Gluconeogenesis via a Novel Mechanism of Transcription Regulation Linked to the Fasted-to-fed Cycle by De Fabiani, Emma, Mitro, Nico, Gilardi, Federica, Caruso, Donatella, Galli, Giovanni, Crestani, Maurizio

“…Bile acid metabolism plays an essential role in cholesterol homeostasis and is critical for the initiation of atherosclerotic disease. However, despite the…”
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Energizing Genetics and Epi-genetics: Role in the Regulation of Mitochondrial Function by Audano, Matteo, Ferrari, Alessandra, Fiorino, Erika, Kuenzl, Martin, Caruso, Donatella, Mitro, Nico, Crestani, Maurizio, De Fabiani, Emma

“…Energy metabolism and mitochondrial function hold a core position in cellular homeostasis. Oxidative metabolism is regulated at multiple levels, ranging from…”
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Transcriptional activation of the cholesterol 7α-hydroxylase gene (CYP7A) by nuclear hormone receptors by Crestani, Maurizio, Sadeghpour, Azita, Stroup, Diane, Galli, Giovanni, Chiang, John Y.L.

“…The gene encoding cholesterol 7α-hydroxylase (CYP7A), the rate-limiting enzyme in bile acid synthesis, is transcriptionally regulated by bile acids and…”
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When food meets man: the contribution of epigenetics to health by De Fabiani, Emma, Mitro, Nico, Gilardi, Federica, Galmozzi, Andrea, Caruso, Donatella, Crestani, Maurizio

“…Post-translational modifications of chromatin contribute to the epigenetic control of gene transcription. The response to food intake and individual nutrients…”
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Insights into the Mechanism of Partial Agonism by Pochetti, Giorgio, Godio, Cristina, Mitro, Nico, Caruso, Donatella, Galmozzi, Andrea, Scurati, Samuele, Loiodice, Fulvio, Fracchiolla, Giuseppe, Tortorella, Paolo, Laghezza, Antonio, Lavecchia, Antonio, Novellino, Ettore, Mazza, Fernando, Crestani, Maurizio

“…The peroxisome proliferator-activated receptors (PPARs) are transcriptional regulators of glucose and lipid metabolism. They are activated by natural ligands,…”
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