Search Results - "CRESSEY, Tim R"
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A pilot program of HIV pre-exposure prophylaxis in Thai youth
Published in PloS one (22-02-2024)“…There are gaps in knowledge and experience of antiretroviral pre-exposure prophylaxis (PrEP) delivery in adolescents. This pilot study enrolled Thai…”
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Continued attendance in a PrEP program despite low adherence and non-protective drug levels among adolescent girls and young women in Kenya: Results from a prospective cohort study
Published in PLoS medicine (12-09-2022)“…Background In sub-Saharan Africa (SSA), adolescent girls and young women (AGYW) ages 15 to 24 years represent <10% of the population yet account for 1 in 5 new…”
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3
Assessment of three antibiotic combination regimens against Gram-negative bacteria causing neonatal sepsis in low- and middle-income countries
Published in Nature communications (10-05-2024)“…Gram-negative bacteria (GNB) are a major cause of neonatal sepsis in low- and middle-income countries (LMICs). Although the World Health Organization (WHO)…”
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Pharmacodynamics of Rivaroxaban and Dabigatran in Adults with Diffuse Large B-Cell Lymphoma Receiving R-CHOP Immunochemotherapy
Published in Pharmaceutics (11-10-2024)“…: Rivaroxaban and dabigatran are commonly used for thromboembolic disease management in active cancer patients. However, limited research explores the impact…”
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Role of efavirenz plasma concentrations on long-term HIV suppression and immune restoration in HIV-infected children
Published in PloS one (16-05-2019)“…To access the long term relationship between efavirenz plasma concentrations and evolution of HIV RNA loads and CD4 cell counts in children. Retrospective…”
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Pilot evaluation of an enzymatic assay for rapid measurement of antiretroviral drug concentrations
Published in Virology journal (15-04-2021)“…Maintaining adequate drug adherence is crucial to ensure the HIV prevention benefits of pre-exposure prophylaxis (PrEP). We developed an enzymatic assay for…”
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Plasma pharmacokinetics and urinary excretion of tenofovir following cessation in adults with controlled levels of adherence to tenofovir disoproxil fumarate
Published in International journal of infectious diseases (01-08-2020)“…•Tenofovir disoproxil fumarate (TDF) is a key drug for HIV prevention and treatment.•Maintaining adherence to TDF is critical for efficacy but can be…”
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Population Pharmacokinetic Modeling of Abacavir/Dolutegravir/Lamivudine to Support a Fixed-Dose Combination in Children with HIV-1
Published in Infectious diseases and therapy (01-08-2024)“…Introduction Once-daily fixed-dose combinations (FDC) containing abacavir (ABC), dolutegravir (DTG), and lamivudine (3TC) have been approved in the US for…”
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Weekends-off efavirenz-based antiretroviral therapy in HIV-infected children, adolescents and young adults (BREATHER): Extended follow-up results of a randomised, open-label, non-inferiority trial
Published in PloS one (23-04-2018)“…Weekends off antiretroviral therapy (ART) may help engage HIV-1-infected young people facing lifelong treatment. BREATHER showed short cycle therapy (SCT; 5…”
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Borrowing information across patient subgroups in clinical trials, with application to a paediatric trial
Published in BMC medical research methodology (20-02-2022)“…Clinical trial investigators may need to evaluate treatment effects in a specific subgroup (or subgroups) of participants in addition to reporting results of…”
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Lack of Association between Adverse Pregnancy Outcomes and Zika Antibodies among Pregnant Women in Thailand between 1997 and 2015
Published in Viruses (22-07-2021)“…Data about Zika virus infection and adverse pregnancy outcomes in Southeast Asia are scarce. We conducted an unmatched case-control study of Zika virus (ZIKV)…”
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Simplifying TREAtment and Monitoring for HIV (STREAM HIV): protocol for a randomised controlled trial of point-of-care urine tenofovir and viral load testing to improve HIV outcomes
Published in BMJ open (05-10-2021)“…IntroductionSubstantial improvements in viral suppression among people living with HIV (PLHIV) are needed to end the HIV epidemic, requiring extensive scale-up…”
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A randomized clinical pharmacokinetic trial of Tenofovir in blood, plasma and urine in adults with perfect, moderate and low PrEP adherence: the TARGET study
Published in BMC infectious diseases (14-07-2017)“…Tenofovir disoproxil fumarate (TDF) is key component of pre-exposure prophylaxis (PrEP) and antiretroviral therapy (ART) for HIV, but existing tools to monitor…”
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14
A Mobile Phone App to Support Adherence to Daily HIV Pre-exposure Prophylaxis Engagement Among Young Men Who Have Sex With Men and Transgender Women Aged 15 to 19 Years in Thailand: Pilot Randomized Controlled Trial
Published in JMIR mHealth and uHealth (21-04-2022)“…Widespread smartphone use provides opportunities for mobile health HIV prevention strategies among at-risk populations. This study aims to investigate…”
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Modeling of In-Utero and Intra-Partum Transmissions to Evaluate the Efficacy of Interventions for the Prevention of Perinatal HIV
Published in PloS one (19-05-2015)“…Antiretroviral treatments decrease HIV mother-to-child transmission through pre/post exposure prophylaxis and reduction of maternal viral load. We modeled…”
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Nevirapine Exposure with WHO Pediatric Weight Band Dosing: Enhanced Therapeutic Concentrations Predicted Based on Extensive International Pharmacokinetic Experience
Published in Antimicrobial Agents and Chemotherapy (01-10-2012)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Correction: Modeling of In-Utero and Intra-Partum Transmissions to Evaluate the Efficacy of Interventions for the Prevention of Perinatal HIV
Published in PloS one (26-06-2015)Get full text
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Correction: Modeling of In-Utero and Intra-Partum Transmissions to Evaluate the Efficacy of Interventions for the Prevention of Perinatal HIV
Published in PloS one (28-08-2015)Get full text
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Expanding options of child-friendly, single-tablet regimens for young children with HIV
Published in The lancet HIV (01-05-2024)Get full text
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Tenofovir versus Placebo to Prevent Perinatal Transmission of Hepatitis B
Published in The New England journal of medicine (08-03-2018)“…Preventing mother-to-child transmission of hepatitis B virus is an opportunity to prevent lifelong infection and associated complications. This randomized,…”
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