Search Results - "CRAWFORD, DARRELL G"

Serum ferritin concentration predicts mortality in patients awaiting liver transplantation by Walker, Nicole M., Stuart, Katherine A., Ryan, Rebecca J., Desai, Shireena, Saab, Sammy, Nicol, Jennifer A., Fletcher, Linda M., G. Crawford, Darrell H.

“…Additional markers are required to identify patients on the orthotopic liver transplant (OLT) waiting list at increased risk of death and adverse clinical…”
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APASL consensus statements and recommendations for hepatitis C prevention, epidemiology, and laboratory testing by Omata, Masao, Kanda, Tatsuo, Wei, Lai, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Dokmeci, A. Kadir, Al-Mahtab, Mamun, McCaughan, Geofferey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Yokosuka, Osamu, Lau, George K. K., Sarin, Shiv Kumar

“…The Asian Pacific Association for the Study of the Liver (APASL) convened an international working party on “APASL consensus statements and recommendations for…”
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Visualizing liver anatomy, physiology and pharmacology using multiphoton microscopy by Wang, Haolu, Liang, Xiaowen, Gravot, Germain, Thorling, Camilla A., Crawford, Darrell H. G., Xu, Zhi Ping, Liu, Xin, Roberts, Michael S.

“…Multiphoton microscopy (MPM) has become increasingly popular and widely used in both basic and clinical liver studies over the past few years. This technology…”
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Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading by McDonald, Cameron J, Rishi, Gautam, Secondes, Eriza S, Ostini, Lesa, Wallace, Daniel F, Crawford, Darrell H G, Sia, Hanlon, Clark, Paul, Subramaniam, V Nathan

“…Atypical iron overload without variation in the five clinically associated hereditary hemochromatosis genes is now recognized; however, their etiology remains…”
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Hepatocellular Necrosis, Fibrosis and Microsomal Activity Determine the Hepatic Pharmacokinetics of Basic Drugs in Right-Heart-Failure-Induced Liver Damage by Li, Peng, Robertson, Thomas A., Zhang, Qian, Fletcher, Linda M., Crawford, Darrell H. G., Weiss, Michael, Roberts, Michael S.

“…ABSTRACT Purpose To explore how liver damage arising from cardio-hepatic syndromes in RHF affect the hepatic pharmacokinetics of basic drugs. Methods The…”
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Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis by Bridle, Kim R, Frazer, David M, Wilkins, Sarah J, Dixon, Jeanette L, Purdie, David M, Crawford, Darrell HG, Subramaniam, V Nathan, Powell, Lawrie W, Anderson, Gregory J, Ramm, Grant A

“…The mechanisms responsible for disturbed iron homoeostasis in hereditary haemochromatosis are poorly understood. However, results of some studies indicate a…”
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Monitoring Immune Checkpoint Regulators as Predictive Biomarkers in Hepatocellular Carcinoma by Shrestha, Ritu, Prithviraj, Prashanth, Anaka, Matthew, Bridle, Kim R, Crawford, Darrell H G, Dhungel, Bijay, Steel, Jason C, Jayachandran, Aparna

“…The global burden of hepatocellular carcinoma (HCC), one of the frequent causes of cancer-related deaths worldwide, is rapidly increasing partly due to the…”
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Necroptosis in Hepatosteatotic Ischaemia-Reperfusion Injury by Baidya, Raji, Crawford, Darrell H G, Gautheron, Jérémie, Wang, Haolu, Bridle, Kim R

“…While liver transplantation remains the sole treatment option for patients with end-stage liver disease, there are numerous limitations to liver…”
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CD73 and PD-L1 as Potential Therapeutic Targets in Gallbladder Cancer by Cao, Lu, Bridle, Kim R, Shrestha, Ritu, Prithviraj, Prashanth, Crawford, Darrell H G, Jayachandran, Aparna

“…Gallbladder cancer (GBC) is one of the most common and aggressive biliary tract cancers with a dismal prognosis. Ongoing clinical trials are evaluating a few…”
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APASL consensus statements and recommendation on treatment of hepatitis C by Omata, Masao, Kanda, Tatsuo, Wei, Lai, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Dokmeci, A. Kadir, Mamun-Al-Mahtab, McCaughan, Geofferey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Yokosuka, Osamu, Lau, George K. K., Sarin, Shiv Kumar

“…The Asian-Pacific Association for the Study of the Liver (APASL) convened an international working party on the “APASL consensus statements and recommendation…”
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APASL HCV guidelines of virus-eradicated patients by DAA on how to monitor HCC occurrence and HBV reactivation by Kanda, Tatsuo, Lau, George K. K., Wei, Lai, Moriyama, Mitsuhiko, Yu, Ming-Lung, Chuang, Wang-Long, Ibrahim, Alaaeldin, Lesmana, Cosmas Rinaldi Adithya, Sollano, Jose, Kumar, Manoj, Jindal, Ankur, Sharma, Barjesh Chander, Hamid, Saeed S., Kadir Dokmeci, A., Mamun-Al-Mahtab, McCaughan, Geoffrey W., Wasim, Jafri, Crawford, Darrell H. G., Kao, Jia-Horng, Ooka, Yoshihiko, Yokosuka, Osamu, Sarin, Shiv Kumar, Omata, Masao

“…In the direct-acting antiviral (DAA) era for hepatitis C virus (HCV) infection, sustained virological response (SVR) is very high, but close attention must be…”
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Therapeutic modulators of hepatic stellate cells for hepatocellular carcinoma by Ruan, Qi, Wang, Haolu, Burke, Leslie J., Bridle, Kim R., Li, Xinxing, Zhao, Chun‐Xia, Crawford, Darrell H.G., Roberts, Michael S., Liang, Xiaowen

“…Hepatocellular carcinoma (HCC) is the most common type of primary tumor in the liver and is a leading cause of cancer‐related death worldwide. Activated…”
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Concise Review: Quantitative Detection and Modeling the In Vivo Kinetics of Therapeutic Mesenchymal Stem/Stromal Cells by Brooks, Anastasia, Futrega, Kathryn, Liang, Xiaowen, Hu, Xiaoling, Liu, Xin, Crawford, Darrell H. G., Doran, Michael R., Roberts, Michael S., Wang, Haolu

“…Mesenchymal stem/stromal cells (MSCs) present a promising tool in cell‐based therapy for treatment of various diseases. Currently, optimization of treatment…”
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Dual Targeting of Sorafenib-Resistant HCC-Derived Cancer Stem Cells by Shrestha, Ritu, Bridle, Kim R., Cao, Lu, Crawford, Darrell H. G., Jayachandran, Aparna

“…Sorafenib, an oral multi-tyrosine kinase inhibitor, has been the first-line therapy for the treatment of patients with advanced HCC, providing a survival…”
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Australian recommendations for the management of hepatocellular carcinoma: a consensus statement by Lubel, John S, Roberts, Stuart K, Strasser, Simone I, Thompson, Alexander J, Philip, Jennifer, Goodwin, Mark, Clarke, Stephen, Crawford, Darrell HG, Levy, Miriam T, Shackel, Nick

“…Introduction Hepatocellular carcinoma (HCC) is a leading cause of cancer deaths both globally and in Australia. Surveillance for HCC in at‐risk populations…”
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Physical comorbidities of post‐traumatic stress disorder in Australian Vietnam War veterans by McLeay, Sarah C, Harvey, Wendy M, Romaniuk, Madeline NM, Crawford, Darrell HG, Colquhoun, David M, Young, Ross McD, Dwyer, Miriam, Gibson, John M, O'Sullivan, Robyn A, Cooksley, Graham, Strakosch, Christopher R, Thomson, Rachel M, Voisey, Joanne, Lawford, Bruce R

“…Objective: To determine whether the prevalence of physical comorbidities in Australian Vietnam War veterans with post‐traumatic stress disorder (PTSD) is…”
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Intravital Multiphoton Imaging of the Selective Uptake of Water-Dispersible Quantum Dots into Sinusoidal Liver Cells by Liang, Xiaowen, Grice, Jeffrey E., Zhu, Yian, Liu, David, Sanchez, Washington Y., Li, Zhen, Crawford, Darrell H. G., Le Couteur, David G., Cogger, Victoria C., Liu, Xin, Xu, Zhi Ping, Roberts, Michael S.

“…Although many studies reporting the organ‐level biodistribution of nanoparticles (NPs) in animals, very few have addressed the fate of NPs in organs at the…”
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Imaging-based vascular-related biomarkers for early detection of acetaminophen-induced liver injury by Wang, Haolu, Burke, Leslie J, Patel, Jatin, Tse, Brian Wc, Bridle, Kim R, Cogger, Victoria C, Li, Xinxing, Liu, Xin, Yang, Haotian, Crawford, Darrell H G, Roberts, Michael S, Gao, Wenchao, Liang, Xiaowen

“…Acetaminophen (APAP) is the foremost cause of drug-induced liver injury in the Western world. Most studies of APAP hepatotoxicity have focused on the…”
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Iron storage disease in Asia-Pacific populations: The importance of non-HFE mutations by McDonald, Cameron J, Wallace, Daniel F, Crawford, Darrell H G, Subramaniam, V Nathan

“…Hereditary hemochromatosis (HH) is a widely recognized and well‐studied condition in European populations. This is largely due to the high prevalence of the…”
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Rapamycin inhibits hepatic fibrosis in rats by attenuating multiple profibrogenic pathways by Bridle, Kim R., Popa, Claudia, Morgan, Maelle L., Sobbe, Amy L., Clouston, Andrew D., Fletcher, Linda M., Crawford, Darrell H. G.

“…Hepatic stellate cell transdifferentiation, epithelial‐mesenchymal cell transition, and the ductular reaction each contribute to the development of hepatic…”
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