Search Results - "CRAMER, Jakob P"
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1
Evolution of the COVID-19 vaccine development landscape
Published in Nature reviews. Drug discovery (01-10-2020)Get full text
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Vaccine-associated enhanced disease: Case definition and guidelines for data collection, analysis, and presentation of immunization safety data
Published in Vaccine (21-05-2021)“…This is a Brighton Collaboration Case Definition of the term “Vaccine Associated Enhanced Disease” to be utilized in the evaluation of adverse events following…”
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A phase 2 study of the bivalent VLP norovirus vaccine candidate in older adults; impact of MPL adjuvant or a second dose
Published in Vaccine (10-08-2020)“…•Dose and adjuvant confirmation trial in adults 60–102 years with young adult cohort.•A single adult dose was as safe and immunogenic in older adults as young…”
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Safety and Immunogenicity of Different Formulations of Norovirus Vaccine Candidate in Healthy Adults: A Randomized, Controlled, Double-Blind Clinical Trial
Published in The Journal of infectious diseases (30-01-2018)“…Bivalent (GI.1 and GII.4) virus-like particle norovirus candidate vaccine formulations were well tolerated and immunogenic, 1 dose inducing immune responses…”
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Travel-associated infection presenting in Europe (2008–12): an analysis of EuroTravNet longitudinal, surveillance data, and evaluation of the effect of the pre-travel consultation
Published in The Lancet infectious diseases (2015)“…Summary Background Travel is important in the acquisition and dissemination of infection. We aimed to assess European surveillance data for travel-related…”
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Multicenter GeoSentinel analysis of rickettsial diseases in international travelers, 1996-2008
Published in Emerging infectious diseases (01-11-2009)“…We investigated epidemiologic and clinical aspects of rickettsial diseases in 280 international travelers reported to the GeoSentinel surveillance Network…”
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Myeloperoxidase Attenuates Pathogen Clearance during Plasmodium yoelii Nonlethal Infection
Published in Infection and immunity (01-01-2017)“…Myeloperoxidase (MPO), a leukocyte-derived enzyme mainly secreted by activated neutrophils, is known to be involved in the immune response during bacterial and…”
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Efficacy and safety of a patch vaccine containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase 3, randomised, double-blind, placebo-controlled field trial in travellers from Europe to Mexico and Guatemala
Published in The Lancet infectious diseases (01-03-2014)“…Summary Background Enterotoxigenic Escherichia coli (ETEC) is a major cause of travellers' diarrhoea. We investigated the efficacy and safety of a skin-patch…”
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Risk assessment in travel medicine: how to obtain, interpret, and use risk data for informing pre-travel advice
Published in Journal of travel medicine (01-01-2015)“…It has been recommended that numerical risk data should be provided during the pre-travel consultation in order for travelers to make informed decisions…”
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Toll-Like Receptor (TLR) Polymorphisms in African Children: Common TLR-4 Variants Predispose to Severe Malaria
Published in Proceedings of the National Academy of Sciences - PNAS (03-01-2006)“…Genetic host factors play a substantial role in susceptibility to and severity of malaria, which continues to cause at least one million deaths per year…”
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Post-treatment haemolysis in severe imported malaria after intravenous artesunate: case report of three patients with hyperparasitaemia
Published in Malaria journal (17-05-2012)“…Parenteral artesunate has been shown to be a superior treatment option compared to parenteral quinine in adults and children with severe malaria. Little…”
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Realising the potential of correlates of protection for vaccine development, licensure and use: short summary
Published in npj vaccines (29-04-2024)“…On 27–29 th of September 2022, Wellcome convened an international multi-stakeholder workshop to discuss the use of Correlates of Protection (CoP) to accelerate…”
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Malaria, Anemia, and Malnutrition in African Children—Defining Intervention Priorities
Published in The Journal of infectious diseases (01-07-2006)“…BackgroundMalaria, anemia, and malnutrition contribute substantially to childhood morbidity in sub-Saharan Africa, but their respective roles and interactions…”
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Regional variation in travel-related illness acquired in Africa, March 1997-May 2011
Published in Emerging infectious diseases (01-04-2014)“…To understand geographic variation in travel-related illness acquired in distinct African regions, we used the GeoSentinel Surveillance Network database to…”
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Duration of Fecal Shedding of Shiga Toxin—Producing Escherichia coli O104:H4 in Patients Infected During the 2011 Outbreak in Germany: A Multicenter Study
Published in Clinical infectious diseases (15-04-2013)“…Background. In May–July 2011, Germany experienced a large food-borne outbreak of Shiga toxin 2—producing Escherichia coli (STEC O104:H4) with 3842 cases,…”
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Armillifer armillatus pentastomiasis in African immigrant, Germany
Published in Emerging infectious diseases (01-03-2013)Get full text
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Delivering Pandemic Vaccines in 100 Days — What Will It Take?
Published in The New England journal of medicine (14-07-2022)“…Implementing best practices could compress vaccine-development timelines in the event of a new pandemic. Further speeding of development will require…”
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SARS-CoV-2 Variants and Vaccines
Published in The New England journal of medicine (08-07-2021)“…Viral variants of concern may emerge with dangerous resistance to the immunity generated by the current vaccines to prevent coronavirus disease 2019…”
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Intermittent Preventive Treatment in Infants as a Means of Malaria Control: a Randomized, Double-Blind, Placebo-Controlled Trial in Northern Ghana
Published in Antimicrobial Agents and Chemotherapy (01-09-2007)“…Errata ( vol. 56 , p. 600 ) Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg…”
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Risk factors for development of hemolytic uremic syndrome in a cohort of adult patients with STEC 0104:H4 infection
Published in PloS one (22-03-2013)“…The outbreak of Shiga toxin producing E.coli O104:H4 in northern Germany in 2011 was one of the largest worldwide and involved mainly adults. Post-diarrheal…”
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