Search Results - "CRAIN, Karen I"

A Lipidomics Analysis of the Relationship Between Dietary Fatty Acid Composition and Insulin Sensitivity in Young Adults by LAWRENCE KIEN, C, BUNN, Janice Y, MUOIO, Deborah M, POYNTER, Matthew E, STEVENS, Robert, BAIN, James, IKAYEVA, Olga, FUKAGAWA, Naomi K, CHAMPAGNE, Catherine M, CRAIN, Karen I, KOVES, Timothy R

“…Relative to diets enriched in palmitic acid (PA), diets rich in oleic acid (OA) are associated with reduced risk of type 2 diabetes. To gain insight into…”
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Dietary saturated fat and monounsaturated fat have reversible effects on brain function and the secretion of pro-inflammatory cytokines in young women by Dumas, Julie A, Bunn, Janice Y, Nickerson, Joshua, Crain, Karen I, Ebenstein, David B, Tarleton, Emily K, Makarewicz, Jenna, Poynter, Matthew E, Kien, C. Lawrence

“…Abstract Background Previous literature suggests that a higher ratio of palmitic acid (PA)/oleic acid (OA) in the diet induces inflammation, which may result…”
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Muscle-Specific Overexpression of PGC-1α Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction by Wong, Kari E, Mikus, Catherine R, Slentz, Dorothy H, Seiler, Sarah E, DeBalsi, Karen L, Ilkayeva, Olga R, Crain, Karen I, Kinter, Michael T, Kien, C Lawrence, Stevens, Robert D, Muoio, Deborah M

“…This study used mice with muscle-specific overexpression of PGC-1α, a transcriptional coactivator that promotes mitochondrial biogenesis, to determine whether…”
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Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood by Kien, C Lawrence, Bunn, Janice Y, Tompkins, Connie L, Dumas, Julie A, Crain, Karen I, Ebenstein, David B, Koves, Timothy R, Muoio, Deborah M

“…Background: The Western diet increases risk of metabolic disease.Objective: We determined whether lowering the ratio of saturated fatty acids to…”
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Pharmacokinetics of omega-3 fatty acids in patients with severe sepsis compared with healthy volunteers: A prospective cohort study by Parikh, Radhika, Bates, Jason H.T., Poynter, Matthew E., Suratt, Benjamin T., Parsons, Polly E., Kien, C. Lawrence, Heyland, Daren K., Crain, Karen I., Martin, Julie, Garudathri, Jayanthi, Stapleton, Renee D.

“…Pharmacokinetics (PK) of pharmaceuticals and pharmaconutrients are poorly understood in critically ill patients, and dosing is often based on healthy subject…”
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Lipidomic evidence that lowering the typical dietary palmitate to oleate ratio in humans decreases the leukocyte production of proinflammatory cytokines and muscle expression of redox-sensitive genes by Kien, C. Lawrence, Bunn, Janice Y., Fukagawa, Naomi K., Anathy, Vikas, Matthews, Dwight E., Crain, Karen I., Ebenstein, David B., Tarleton, Emily K., Pratley, Richard E., Poynter, Matthew E.

“…We recently reported that lowering the high, habitual palmitic acid (PA) intake in ovulating women improved insulin sensitivity and both inflammatory and…”
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Increased palmitate intake: higher acylcarnitine concentrations without impaired progression of β-oxidation by Kien, C Lawrence, Matthews, Dwight E, Poynter, Matthew E, Bunn, Janice Y, Fukagawa, Naomi K, Crain, Karen I, Ebenstein, David B, Tarleton, Emily K, Stevens, Robert D, Koves, Timothy R, Muoio, Deborah M

“…Palmitic acid (PA) is associated with higher blood concentrations of medium-chain acylcarnitines (MCACs), and we hypothesized that PA may inhibit progression…”
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Increased palmitate intake: higher acylcarnitine concentrations without impaired progression of β-oxidation1[S] by Kien, C.Lawrence, Matthews, Dwight E., Poynter, Matthew E., Bunn, Janice Y., Fukagawa, Naomi K., Crain, Karen I., Ebenstein, David B., Tarleton, Emily K., Stevens, Robert D., Koves, Timothy R., Muoio, Deborah M.

“…Palmitic acid (PA) is associated with higher blood concentrations of medium-chain acylcarnitines (MCACs), and we hypothesized that PA may inhibit progression…”
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Substituting dietary monounsaturated fat for saturated fat lowers inflammasome activation observed on a high saturated fat diet by Kien, Craig Lawrence, Crain, Karen I., Bunn, Janice Y., Fukagawa, Naomi K., Poynter, Matthew E.

“…Abstract only Altered lipid homeostasis (obesity) is linked to inflammation and defective insulin signaling. In the presence of palmitic acid (PA), but not…”
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Muscle-Specific Overexpression of PGC-1a Does Not Augment Metabolic Improvements in Response to Exercise and Caloric Restriction by Wong, Kari E, Mikus, Catherine R, Slentz, Dorothy H, Seiler, Sarah E, DeBalsi, Karen L, Ilkayeva, Olga R, Crain, Karen I, Kinter, Michael T, Kien, C Lawrence, Stevens, Robert D, Muoio, Deborah M

“…This study used mice with muscle-specific overexpression of PGC-1α, a transcriptional coactivator that promotes mitochondrial biogenesis, to determine whether…”
Get full text

Lipidomic evidence that lowering the typical dietary palmitate to oleate ratio in humans decreases the leukocyte production of pro-inflammatory cytokines and muscle expression of redox-sensitive genes by Kien, C. Lawrence, Bunn, Janice Y., Fukagawa, Naomi K., Anathy, Vikas, Matthews, Dwight E., Crain, Karen I., Ebenstein, David B., Tarleton, Emily K., Pratley, Richard E., Poynter, Matthew E.

“…We recently reported that lowering the high, habitual palmitic acid (PA) intake in ovulating women improved insulin sensitivity and both inflammatory and…”
Get full text

Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood123 by Kien, C Lawrence, Bunn, Janice Y, Tompkins, Connie L, Dumas, Julie A, Crain, Karen I, Ebenstein, David B, Koves, Timothy R, Muoio, Deborah M

“…The Western diet increases risk of metabolic disease. We determined whether lowering the ratio of saturated fatty acids to monounsaturated fatty acids in the…”
Get full text

Substituting dietary monounsaturated fat for saturated fat is associated with increased daily physical activity and resting energy expenditure and with changes in mood by Kien, Craig Lawrence, Bunn, Janice Y., Tompkins, Connie L., Dumas, Julie A., Crain, Karen I., Ebenstein, David B., Koves, Timothy R., Muoio, Deborah M.

“…Abstract only The Western Diet has been linked to obesity, an imbalance of energy intake and expenditure. Studies have emphasized how dietary composition…”
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