Search Results - "CRAIG, R. W"

MCL1 provides a window on the role of the BCL2 family in cell proliferation, differentiation and tumorigenesis by CRAIG, R. W

“…The MCL1 gene (myeloid cell leukemia-1) was discovered serendipitously about a decade ago and proved to be a member of the emerging BCL2 gene family. Ongoing…”
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MCL1, a Gene Expressed in Programmed Myeloid Cell Differentiation, has Sequence Similarity to BCL2 by Kozopas, Karen M., Yang, Tao, Buchan, Heather L., Zhou, Ping, Craig, Ruth W.

“…During their lifespan, immature cells normally pass through sequential transitions to a differentiated state and eventually undergo cell death. This…”
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Participation of p53 protein in the cellular response to DNA damage by KASTAN, M. B, ONYEKWERE, O, SIDRANSKY, D, VOGELSTEIN, B, CRAIG, R. W

“…The inhibition of replicative DNA synthesis that follows DNA damage may be critical for avoiding genetic lesions that could contribute to cellular…”
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Mcl-1, a Bcl-2 family member, delays the death of hematopoietic cells under a variety of apoptosis-inducing conditions by ZHOU, P, QIAN, L, KOZOPAS, K. M, CRAIG, R. W

“…Mcl-1 is a member of the Bcl-2 family that was identified based on increased expression in myeloblastic leukemia cells undergoing differentiation. Mcl-1 was…”
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Mobile Aortic Atheroma and Systemic Emboli: Efficacy of Anticoagulation and Influence of Plaque Morphology on Recurrent Stroke by Dressler, Frederick A, Craig, William R, Castello, Ramon, Labovitz, Arthur J

“…Objectives. We sought to determine the influence of plaque morphology and warfarin anticoagulation on the risk of recurrent emboli in patients with mobile…”
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Mcl-1, a member of the Bcl-2 family, delays apoptosis induced by c-Myc overexpression in Chinese hamster ovary cells by REYNOLDS, J. E, TAO YANG, LIPING QIAN, JENKINSON, J. D, PING ZHOU, EASTMAN, A, CRAIG, R. W

“…Mcl-1, a protein increased early in the differentiation of human myeloblastic ML-1 cells, has sequence similarity to Bcl-2. In the present study, we determined…”
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Expression of the antiapoptotic MCL1 gene product is regulated by a mitogen activated protein kinase-mediated pathway triggered through microtubule disruption and protein kinase C by TOWNSEND, K. J, TRUSTY, J. L, TRAUPMAN, M. A, EASTMAN, A, CRAIG, R. W

“…Members of both the mitogen activated protein (MAP) kinase and BCL2 gene families, acting in concert with other gene products, are involved in the regulation…”
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Metoclopramide, thickened feedings, and positioning for gastro-oesophageal reflux in children under two years by Craig, W R, Hanlon-Dearman, A, Sinclair, C, Taback, S, Moffatt, M

“…Gastro-esophageal reflux (GER) is the refluxing of gastric contents into the esophagus. Fifty per cent of all infants 0 to 3 months regurgitate at least once a…”
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Abnormal coronary flow velocity reserve after coronary artery stenting in patients : Role of relative coronary reserve to assess potential mechanisms by KERN, M. J, PURI, S, MECHEM, C. J, DUBOIS-RANDE, J.-L, BACH, R. G, DONOHUE, T. J, DUPOUY, P, CARACCIOLO, E. A, CRAIG, W. R, AGUIRRE, F, APTECAR, E, WOLFORD, T. L

“…Absolute coronary flow velocity reserve (CVR) after stenting may remain abnormal as a result of several different mechanisms. Relative CVR…”
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MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol by DOMINA, Aaron M, VRANA, Julie A, GREGORY, Mark A, HANN, Stephen R, CRAIG, Ruth W

“…BCL2 family members are subject to regulation at multiple levels, providing checks on their ability to contribute to tumorigenesis. However, findings on…”
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SKIP OVIPOSITION BEHAVIOR OF LABORATORY, FIELD AND TRANSGENIC STRAIN OF AEDES AEGYPTI (L.) by Nazni, W A, Bandara, M R S S, Azahari, A H, Craig, R W, Lee, H L

“…The oviposition behavior of 3 strains of Aedes aegypti (L.) namely, laboratory-reared, field collected and transgenic strain was studied. Newly emerged…”
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Protection from cell death by mcl-1 is mediated by membrane hyperpolarization induced by K(+) channel activation by Wang, L, Zhou, P, Craig, R W, Lu, L

“…Mcl-1, a member of the Bcl-2 family, has been identified as an inhibitor of apoptosis induced by anticancer agents and radiation in myeloblastic leukemia…”
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Induction of BCL2 family member MCL1 as an early response to DNA damage by ZHAN, Q, BIESZCZAD, C. K, BAE, I, FORNACE, A. J, CRAIG, R. W

“…When ML-1 human myeloid leukemia cells are exposed to DNA damaging agents, they exhibit dramatic changes in the expression of a variety of gene products. This…”
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Levels of p53 protein increase with maturation in human hematopoietic cells by KASTAN, M. B, RADIN, A. I, KUERBITZ, S. J, ONYEKWERE, O, WOLKOW, C. A, CIVIN, C. I, STONE, K. D, WOO, T, RAVINDRANATH, Y, CRAIG, R. W

“…Transfection of the wild-type p53 gene into malignant cell lines usually results in an inhibition of proliferation. However, the physiological function of the…”
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Suppression of Tumorigenicity in Hybrids of Normal and Oncogene-Transformed CHEF Cells by Craig, Ruth W., Sager, Ruth

“…Somatic cell hybridization experiments were carried out to determine whether normal cells have the ability to suppress the transforming effects of a defined…”
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Mcl-1 in Transgenic Mice Promotes Survival in a Spectrum of Hematopoietic Cell Types and Immortalization in the Myeloid Lineage by Zhou, Ping, Qian, Liping, Bieszczad, Christine K., Noelle, Randolph, Binder, Michael, Levy, Norman B., Craig, Ruth W.

“…Mcl-1 is a member of the Bcl-2 family that is expressed in early monocyte differentiation and that can promote viability on transfection into immature myeloid…”
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Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage by MICHELS, Jorg, O'NEILL, Jason W, PACKHAM, Graham, DALLMAN, Claire L, MOUZAKITI, Amalia, HABENS, Fay, BRIMMELL, Matthew, ZHANG, Kam Y. J, CRAIG, Ruth W, MARCUSSON, Eric G, JOHNSON, Peter W. M

“…Enforced expression of the antiapoptotic Bcl-2 family protein Mcl-1 promotes lymphomagenesis in the mouse; however, the functional role of Mcl-1 in human…”
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MCL1 transgenic mice exhibit a high incidence of B-cell lymphoma manifested as a spectrum of histologic subtypes by Zhou, Ping, Levy, Norman B., Xie, Haiyi, Qian, Liping, Lee, Chi-Yu Gregory, Gascoyne, Randy D., Craig, Ruth W.

“…Viability-promoting genes such as BCL2 play an important role in human cancer but do not directly cause aggressive tumors. BCL2 transgenic mice develop…”
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Exon Skipping in Mcl-1 Results in a Bcl-2 Homology Domain 3 Only Gene Product That Promotes Cell Death by Bingle, Colin D., Craig, Ruth W., Swales, Brenka M., Singleton, Vanessa, Zhou, Ping, Whyte, Moira K.B.

“…Mcl-1 is a member of the Bcl-2 family that is regulated transcriptionally and post-transcriptionally, with expression of the full-length Mcl-1-encoded gene…”
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Nebulized Budesonide and Oral Dexamethasone for Treatment of Croup: A Randomized Controlled Trial by Klassen, Terry P, Craig, William R, Moher, David, Osmond, Martin H, Pasterkamp, Hans, Sutcliffe, Terry, Watters, Lise K, Rowe, Peter C

“…CONTEXT.— The effectiveness of glucocorticoids for patients with croup is well established but it remains uncertain which glucocorticoid regimen is most…”
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