Search Results - "CRAFT, John A"
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Etifoxine reverses weight gain and alters the colonic bacterial community in a mouse model of obesity
Published in Biochemical pharmacology (01-10-2020)“…[Display omitted] Obesity is intimately associated with diet and dysbiosis of gut microorganisms but anxiolytics, widely used in treatment of psychiatric…”
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2
Chinese medicine, Qijudihuang pill, mediates cholesterol metabolism and regulates gut microbiota in high-fat diet-fed mice, implications for age-related macular degeneration
Published in Frontiers in immunology (12-10-2023)“…Background Traditional Chinese Medicines have been used for thousands of years but without any sound empirical basis. One such preparation is the Qijudihuang…”
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3
Pyrosequencing of Mytilus galloprovincialis cDNAs: tissue-specific expression patterns
Published in PloS one (25-01-2010)“…Mytilus species are important in marine ecology and in environmental quality assessment, yet their molecular biology is poorly understood. Molecular aspects of…”
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4
Annual variation in the levels of transcripts of sex-specific genes in the mantle of the common mussel, Mytilus edulis
Published in PloS one (30-11-2012)“…Mytilus species are used as sentinels for the assessment of environmental health but sex or stage in the reproduction cycle is rarely considered even though…”
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5
In silico analysis of bacterial metabolism of glutamate and GABA in the gut in a rat model of obesity and type 2 diabetes
Published in Bioscience of Microbiota, Food and Health (01-01-2022)“…Dysbiosis of gut microbiota has adverse effects on host health. This study aimed to determine the effects of changes of faecal microbiota in obese and diabetic…”
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6
Characterisation of gut microbiota of obesity and type 2 diabetes in a rodent model
Published in Bioscience of Microbiota, Food and Health (01-01-2021)“…Various studies have suggested that the gut microbiome interacts with the host and may have a significant role in the aetiology of obesity and Type 2 Diabetes…”
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7
Hepatic transcriptomic and metabolomic responses in the Stickleback ( Gasterosteus aculeatus) exposed to ethinyl-estradiol
Published in Aquatic toxicology (05-05-2010)“…An established three-spined stickleback ( Gasterosteus aculeatus) cDNA array was expanded to 14,496 probes with the addition of hepatic clones derived from…”
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Hepatic Transcriptomic and Metabolomic Responses in the Stickleback (Gasterosteus aculeatus) Exposed to Environmentally Relevant Concentrations of Dibenzanthracene
Published in Environmental science & technology (15-08-2009)“…A three-spined stickleback (Gasterosteus aculeatus) cDNA array and one-dimensional 1H nuclear magnetic resonance (NMR) spectroscopy-based metabolomics…”
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9
Dysregulation of lipid metabolism in the liver of Tspo knockout mice
Published in Biochimica et biophysica acta. Molecular and cell biology of lipids (01-01-2025)“…The translocator protein, TSPO, has been implicated in a wide range of cellular processes exerted from its position in the outer mitochondrial membrane from…”
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10
Histological Characterization of the Dicer1 Mutant Zebrafish Retina
Published in Journal of Ophthalmology (01-01-2015)“…DICER1, a multidomain RNase III endoribonuclease, plays a critical role in microRNA (miRNA) and RNA-interference (RNAi) functional pathways. Loss of Dicer1…”
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11
Transcriptome-wide changes associated with the reproductive behaviour of male guppies exposed to 17α-ethinyl estradiol
Published in Environmental pollution (1987) (01-02-2021)“…Although many pharmaceutical compounds (and their metabolites) can induce harmful impacts at the molecular, physiological and behavioural levels, their…”
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Exposure to 17α-ethinyl estradiol impairs courtship and aggressive behaviour of male sand gobies ( Pomatoschistus minutus)
Published in Chemosphere (Oxford) (01-04-2010)“…Endocrine disrupting chemicals (EDCs), natural or manmade, are known to interfere with the endocrinology of organisms and also cause behavioural changes. The…”
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13
Key metabolic pathways involved in xenobiotic biotransformation and stress responses revealed by transcriptomics of the mangrove oyster Crassostrea brasiliana
Published in Aquatic toxicology (01-09-2015)“…•The transcriptome of the mangrove oyster Crassostrea brasiliana was sequenced.•The sequencing effort dramatically expanded the existing cDNA sequences…”
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14
A light in the darkness: New biotransformation genes, antioxidant parameters and tissue-specific responses in oysters exposed to phenanthrene
Published in Aquatic toxicology (01-07-2014)“…•New phase I and II genes were identified in the oyster Crassostrea brasiliana.•CYP and GST genes were mainly induced in gill, not in digestive…”
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15
Characterisation of the transcriptome of male and female wild-type guppy brains with RNA-Seq and consequences of exposure to the pharmaceutical pollutant, 17α-ethinyl estradiol
Published in Aquatic toxicology (01-05-2017)“…•We explored the effects of EE2 on brain transcriptome in male and female guppy.•The effects were assessed using Illumina sequencing (MiSeq and HiSeq)…”
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Integrating Omic Technologies into Aquatic Ecological Risk Assessment and Environmental Monitoring: Hurdles, Achievements, and Future Outlook
Published in Environmental health perspectives (01-01-2010)“…Background: In this commentary we present the findings from an international consortium on fish toxicogenomics sponsored by the U.K. Natural Environment…”
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Differential expression of vitellogenin and oestrogen receptor genes in the liver of zebrafish, Danio Rerio
Published in Analytical & bioanalytical chemistry (Print) (01-01-2010)“…Environmental oestrogens are responsible for adverse effects in fish that affect reproduction. Availability of model fish to study the differential effects of…”
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Journal Article Conference Proceeding -
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An endocrine disrupting chemical changes courtship and parental care in the sand goby
Published in Aquatic toxicology (10-05-2010)“…Endocrine disrupting chemicals (EDCs) are a diverse group of compounds that can mimic, block or modulate the synthesis of natural hormones. They are known to…”
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Sand goby ( Pomatoschistus minutus) males exposed to an endocrine disrupting chemical fail in nest and mate competition
Published in Hormones and behavior (01-09-2009)“…Endocrine disrupting chemicals (EDCs) are a widely studied group of chemicals that interfere with the endocrinology of organisms. So far, few studies have…”
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20
Effects of 17α-ethinyl estradiol exposure on estrogen receptors α and β and vitellogenins A, B and C mRNA expression in the liver of sand goby (Pomatoschistus minutus)
Published in Marine environmental research (01-05-2014)“…This study aims to characterize the estrogen receptor (er) in sand goby (Pomatoschistus minutus) and determine the temporal effects of 17α-ethinyl estradiol…”
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Journal Article Conference Proceeding