Search Results - "CRAFT, Joe"

The pathogenesis of systemic lupus erythematosus—an update by Choi, Jinyoung, Kim, Sang Taek, Craft, Joe

“…Highlights ► Innate effectors are critical for the lupus phenotype. ► Aberrant adaptive immune responses promote disease progression in SLE. ► Dissection of…”
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T Follicular Regulatory Cells: Choreographers of Productive Germinal Center Responses by Lu, Yisi, Craft, Joe

“…T follicular regulatory cells, or Tfr cells, are a discernable population of regulatory T (Treg) cells that migrate to the B cell follicle and germinal center…”
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Disruption of Pathogenic Cellular Networks by IL-21 Blockade Leads to Disease Amelioration in Murine Lupus by Choi, Jin-Young, Seth, Abhinav, Kashgarian, Michael, Terrillon, Sonia, Fung, Emma, Huang, Lili, Wang, Li Chun, Craft, Joe

“…Systemic lupus erythematosus (lupus) is characterized by autoantibody-mediated organ injury. Follicular Th (Tfh) cells orchestrate physiological germinal…”
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A Critical Role of IL-21-Induced BATF in Sustaining CD8-T-Cell-Mediated Chronic Viral Control by Xin, Gang, Schauder, David M., Lainez, Begoña, Weinstein, Jason S., Dai, Zhengxi, Chen, Yuhong, Esplugues, Enric, Wen, Renren, Wang, Demin, Parish, Ian A., Zajac, Allan J., Craft, Joe, Cui, Weiguo

“…Control of chronic viral infections by CD8 T cells is critically dependent on CD4 help. In particular, helper-derived IL-21 plays a key role in sustaining the…”
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Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus by Shah, Kamini, Lee, Won-Woo, Lee, Seung-Hyun, Kim, Sang Hyun, Kang, Seong Wook, Craft, Joe, Kang, Insoo

“…Interleukin (IL)-17 is a proinflammatory cytokine that is produced largely by a unique CD4(+) T-helper (Th) subset called Th17 cells. The development of Th17…”
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Human Extrafollicular CD4 + Th Cells Help Memory B Cells Produce Igs by Kim, Sang Taek, Choi, Jin-Young, Lainez, Begona, Schulz, Vincent P, Karas, David E, Baum, Eric D, Setlur, Jennifer, Gallagher, Patrick G, Craft, Joe

“…Follicular helper T (Tfh) cells are necessary for germinal center B cell maturation during primary immune responses; however, the T cells that promote humoral…”
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Local Triggering of the ICOS Coreceptor by CD11c+ Myeloid Cells Drives Organ Inflammation in Lupus by Teichmann, Lino L., Cullen, Jaime L., Kashgarian, Michael, Dong, Chen, Craft, Joe, Shlomchik, Mark J.

“…The inducible T cell costimulator (ICOS) is a potent promoter of organ inflammation in murine lupus. ICOS stimulates T follicular helper cell differentiation…”
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Gamma Interferon Plays a Crucial Early Antiviral Role in Protection against West Nile Virus Infection by SHRESTHA, Bimmi, TIAN WANG, SAMUEL, Melanie A, WHITBY, Kevin, CRAFT, Joe, FIKRIG, Erol, DIAMOND, Michael S

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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The transforming growth factor beta signaling pathway is critical for the formation of CD4 T follicular helper cells and isotype-switched antibody responses in the lung mucosa by Marshall, Heather D, Ray, John P, Laidlaw, Brian J, Zhang, Nianzhi, Gawande, Dipika, Staron, Matthew M, Craft, Joe, Kaech, Susan M

“…T follicular helper cells (Tfh) are crucial for the initiation and maintenance of germinal center (GC) reactions and high affinity, isotype-switched antibody…”
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HIF-1 regulates pathogenic cytotoxic T cells in lupus skin disease by Little, Alicia J, Chen, Ping-Min, Vesely, Matthew D, Khan, Rahanna N, Fiedler, Jacob, Garritano, James, Maisha, Fahrisa I, McNiff, Jennifer M, Craft, Joe

“…Cutaneous lupus erythematosus (CLE) is a disfiguring autoimmune skin disease characterized by an inflammatory infiltrate rich in T cells, which are strongly…”
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T follicular helper cell heterogeneity: Time, space, and function by Song, Wenzhi, Craft, Joe

“…Summary T follicular helper (Tfh) cells play a crucial role in orchestrating the humoral arm of adaptive immune responses. Mature Tfh cells localize to…”
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IL-10 signaling in CD4+ T cells is critical for the pathogenesis of collagen-induced arthritis by Tao, Jian, Kamanaka, Masahito, Hao, Jianlei, Hao, Zhifang, Jiang, Xi, Craft, Joe E, Flavell, Richard A, Wu, Zhenzhou, Hong, Zhangyong, Zhao, Liqing, Yin, Zhinan

“…IL-10 is a very important anti-inflammatory cytokine. However, the role of this cytokine in T cells in the pathogenesis of collagen-induced arthritis is…”
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Defective Control of Latent Epstein-Barr Virus Infection in Systemic Lupus Erythematosus by Kang, Insoo, Quan, Timothy, Nolasco, Helena, Park, Sung-Hwan, Hong, Myung Sun, Crouch, Jill, Pamer, Eric G, Howe, John Greg, Craft, Joe

“…EBV infection is more common in patients with systemic lupus erythematosus (SLE) than in control subjects, suggesting that this virus plays an etiologic role…”
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IL-10 Regulates Murine Lupus by Yin, Zhinan, Bahtiyar, Gul, Zhang, Na, Liu, Lanzhen, Zhu, Ping, Robert, Marie E, McNiff, Jennifer, Madaio, Michael P, Craft, Joe

“…MRL/MpJ-Tnfrsf6(lpr) (MRL/MpJ-Fas(lpr); MRL-Fas(lpr)) mice develop a spontaneous lupus syndrome closely resembling human systemic lupus erythematosus. To…”
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T Follicular Helper Cell Heterogeneity by Song, Wenzhi, Craft, Joe

“…T follicular helper (Tfh) cells specialize in helping B cells and are therefore critical contributors to the generation of humoral immunity. Tfh cells aid…”
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Spatial and functional heterogeneity of follicular helper T cells in autoimmunity by Seth, Abhinav, Craft, Joe

“…•Tfh cells drive isotype switch and affinity maturation of pathogenic autoantibodies.•Tfh cell subsets acquire unique functional properties based on the…”
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CBLs downregulation foretells T cell ubiquitination leading to autoimmunity by Vidyarthi, Aurobind, Craft, Joe

“…In a study published in the July issue of Immunity, Li et al. demonstrate that expression of the E3 ubiquitin ligases CBL and CBL-B is downregulated in Tfh…”
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Editing Antigen Presentation: Antigen Transfer between Human B Lymphocytes and Macrophages Mediated by Class A Scavenger Receptors by Harvey, Bohdan P, Quan, Timothy E, Rudenga, Benjamin J, Roman, Robert M, Craft, Joe, Mamula, Mark J

“…B lymphocytes can function independently as efficient APCs. However, our previous studies demonstrate that both dendritic cells and macrophages are necessary…”
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Reply by Craft, Joe, Weinstein, Jason

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Reply by Craft, Joe, Weinstein, Jason

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