Search Results - "COX, R. S"

Genome-wide association study of cognitive functions and educational attainment in UK Biobank (N=112 151) by Davies, G, Marioni, R E, Liewald, D C, Hill, W D, Hagenaars, S P, Harris, S E, Ritchie, S J, Luciano, M, Fawns-Ritchie, C, Lyall, D, Cullen, B, Cox, S R, Hayward, C, Porteous, D J, Evans, J, McIntosh, A M, Gallacher, J, Craddock, N, Pell, J P, Smith, D J, Gale, C R, Deary, I J

“…People’s differences in cognitive functions are partly heritable and are associated with important life outcomes. Previous genome-wide association (GWA)…”
Get full text

Validation of a polygenic risk score for frailty in the Lothian Birth Cohort 1936 and English longitudinal study of ageing by Flint, J. P., Welstead, M., Cox, S. R., Russ, T. C., Marshall, A., Luciano, M.

“…Frailty is a complex trait. Twin studies and high-powered Genome Wide Association Studies conducted in the UK Biobank have demonstrated a strong genetic basis…”
Get full text

Structural brain imaging correlates of general intelligence in UK Biobank by Cox, S.R., Ritchie, S.J., Fawns-Ritchie, C., Tucker-Drob, E.M., Deary, I.J.

“…The associations between indices of brain structure and measured intelligence are unclear. This is partly because the evidence to-date comes from mostly small…”
Get full text

Three major dimensions of human brain cortical ageing in relation to cognitive decline across the eighth decade of life by Cox, S. R., Harris, M. A., Ritchie, S. J., Buchanan, C. R., Valdés Hernández, M. C., Corley, J., Taylor, A. M., Madole, J. W., Harris, S. E., Whalley, H. C., McIntosh, A. M., Russ, T. C., Bastin, M. E., Wardlaw, J. M., Deary, I. J., Tucker-Drob, E. M.

“…Different brain regions can be grouped together, based on cross-sectional correlations among their cortical characteristics; this patterning has been used to…”
Get full text

Genetic contributions to Trail Making Test performance in UK Biobank by Hagenaars, S P, Cox, S R, Hill, W D, Davies, G, Liewald, D C M, Harris, S E, McIntosh, A M, Gale, C R, Deary, I J

“…The Trail Making Test (TMT) is a widely used test of executive function and has been thought to be strongly associated with general cognitive function. We…”
Get full text

Cerebral small vessel disease burden and longitudinal cognitive decline from age 73 to 82: the Lothian Birth Cohort 1936 by Hamilton, O. K. L., Cox, S. R., Okely, J. A., Conte, F., Ballerini, L., Bastin, M. E., Corley, J., Taylor, A. M., Page, D., Gow, A. J., Muñoz Maniega, S., Redmond, P., Valdés-Hernández, M. del C., Wardlaw, J. M., Deary, I. J.

“…Slowed processing speed is considered a hallmark feature of cognitive decline in cerebral small vessel disease (SVD); however, it is unclear whether SVD’s…”
Get full text

Polygenic risk score for schizophrenia and structural brain connectivity in older age: A longitudinal connectome and tractography study by Alloza, C., Cox, S.R., Blesa Cábez, M., Redmond, P., Whalley, H.C., Ritchie, S.J., Muñoz Maniega, S., Valdés Hernández, M. del C., Tucker-Drob, E.M., Lawrie, S.M., Wardlaw, J.M., Deary, I.J., Bastin, M.E.

“…Higher polygenic risk score for schizophrenia (szPGRS) has been associated with lower cognitive function and might be a predictor of decline in brain structure…”
Get full text

Associations between total MRI-visible small vessel disease burden and domain-specific cognitive abilities in a community-dwelling older-age cohort by Hamilton, OKL, Cox, SR, Ballerini, L, Bastin, ME, Corley, J, Gow, AJ, Muñoz Maniega, S, Redmond, P, Valdés Hernández, M del C, Wardlaw, JM, Deary, IJ

“…•Greater SVD burden associates with poorer abilities in all major cognitive domains.•SVD associates with memory and visuospatial due to covariance with general…”
Get full text

Safety, pharmacokinetics and use of the novel NK-1 receptor antagonist maropitant (CereniaTM) for the prevention of emesis and motion sickness in cats by HICKMAN, M.A, COX, S.R, MAHABIR, S, MISKELL, C, LIN, J, BUNGER, A, McCALL, R.B

“…The present study characterizes the safety, pharmacokinetics, and anti-emetic effects of the selective NK-1 receptor antagonist maropitant in the cat. Safety…”
Get full text

Healthy cognitive ageing in the Lothian Birth Cohort studies: marginal gains not magic bullet by Corley, J, Cox, S R, Deary, I J

“…In the face of shifting demographics and an increase in human longevity, it is important to examine carefully what is known about cognitive ageing, and to…”
Get more information

Brain age predicts mortality by Cole, J H, Ritchie, S J, Bastin, M E, Valdés Hernández, M C, Muñoz Maniega, S, Royle, N, Corley, J, Pattie, A, Harris, S E, Zhang, Q, Wray, N R, Redmond, P, Marioni, R E, Starr, J M, Cox, S R, Wardlaw, J M, Sharp, D J, Deary, I J

“…Age-associated disease and disability are placing a growing burden on society. However, ageing does not affect people uniformly. Hence, markers of the…”
Get full text

Population pharmacokinetics of mavacoxib in osteoarthritic dogs by COX, S.R, LIAO, S, PAYNE-JOHNSON, M, ZIELINSKI, R.J, STEGEMANN, M.R

“…Cox, S. R., Liao, S., Payne-Johnson, M., Zielinski, R. J., Stegemann, M. R. Population pharmacokinetics of mavacoxib in osteoarthritic dogs. J. vet. Pharmacol…”
Get full text

pharmacokinetics of maropitant, a novel neurokinin type-1 receptor antagonist, in dogs by BENCHAOUI, H.A, COX, S.R, SCHNEIDER, R.P, BOUCHER, J.F, CLEMENCE, R.G

“…Maropitant is the first NK₁ receptor antagonist developed to treat and prevent emesis in dogs; it is administered by subcutaneous (s.c.) injection at 1 mg/kg,…”
Get full text

Pharmacokinetics of ceftiofur crystalline‐free acid sterile suspension in the equine by COLLARD, W. T, COX, S. R, LESMAN, S. P, GROVER, G. S, BOUCHER, J. F, HALLBERG, J. W, ROBINSON, J. A, BROWN, S. A

“…Collard, W. T., Cox, S. R., Lesman, S. P., Grover, G. S., Boucher, J. F., Hallberg, J. W., Robinson, J. A., Brown, S. A. Pharmacokinetics of ceftiofur…”
Get full text

The pharmacokinetics of maropitant citrate dosed orally to dogs at 2 mg/kg and 8 mg/kg once daily for 14 days consecutive days by Lesman, S. P., Boucher, J. F., Grover, G. S., Cox, S. R., Bidgood, T. L.

“…The pharmacokinetics of maropitant were evaluated in beagle dogs dosed orally with Cerenia® tablets (Pfizer Animal Health) once daily for 14 consecutive days…”
Get full text

Linear accelerator-based stereotaxic radiosurgery for brain metastases:the influence of number of lesions on survival by Joseph, J, Adler, J R, Cox, R S, Hancock, S L

“…To evaluate the influence of the number of brain metastases on survival after stereotaxic radiosurgery and factors that affect the risk of delayed radiation…”
Get more information

Transcutaneous ultrasound level check for selective dorsal rhizotomy by Gelder, C. L., Sataite, I., Chave-Cox, R. S., Goodden, J. R.

“…Aim Single-level selective dorsal rhizotomy (SDR) surgery requires an intra-operative level check to identify the L1 vertebral level or the conus medullaris…”
Get full text

Correction: Transcutaneous ultrasound level check for selective dorsal rhizotomy by Gelder, C. L., Sataite, I., Chave-Cox, R. S., Goodden, J. R.

Get full text

White matter, cognition and psychotic-like experiences in UK Biobank by Bosma, M J, Cox, S R, Ziermans, T, Buchanan, C R, Shen, X, Tucker-Drob, E M, Adams, M J, Whalley, H C, Lawrie, S M

“…Psychotic-like experiences (PLEs) are risk factors for the development of psychiatric conditions like schizophrenia, particularly if associated with distress…”
Get more information

Association of polygenic risk for major psychiatric illness with subcortical volumes and white matter integrity in UK Biobank by Reus, L. M., Shen, X., Gibson, J., Wigmore, E., Ligthart, L., Adams, M. J., Davies, G., Cox, S. R., Hagenaars, S. P., Bastin, M. E., Deary, I. J., Whalley, H. C., McIntosh, A. M.

“…Major depressive disorder (MDD), schizophrenia (SCZ) and bipolar disorder (BP) are common, disabling and heritable psychiatric diseases with a complex…”
Get full text