Search Results - "COX, Helen S"
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Impact of Xpert MTB/RIF for TB diagnosis in a primary care clinic with high TB and HIV prevalence in South Africa: a pragmatic randomised trial
Published in PLoS medicine (01-11-2014)“…Xpert MTB/RIF is approved for use in tuberculosis (TB) and rifampicin-resistance diagnosis. However, data are limited on the impact of Xpert under routine…”
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Xpert MTB/RIF versus sputum microscopy as the initial diagnostic test for tuberculosis: a cluster-randomised trial embedded in South African roll-out of Xpert MTB/RIF
Published in The Lancet global health (01-08-2015)“…Summary Background In South Africa, sputum smear microscopy has been replaced with Xpert MTB/RIF as the initial diagnostic test for tuberculosis. In a…”
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3
Adverse events among HIV/MDR-TB co-infected patients receiving antiretroviral and second line anti-TB treatment in Mumbai, India
Published in PloS one (11-07-2012)“…Significant adverse events (AE) have been reported in patients receiving medications for multidrug- and extensively-drug-resistant tuberculosis (MDR-TB &…”
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Loss from treatment for drug resistant tuberculosis: risk factors and patient outcomes in a community-based program in Khayelitsha, South Africa
Published in PloS one (18-03-2015)“…A community based drug resistant tuberculosis (DR-TB) program has been incrementally implemented in Khayelitsha, a high HIV and TB burden community in South…”
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5
Ambulatory multi-drug resistant tuberculosis treatment outcomes in a cohort of HIV-infected patients in a slum setting in Mumbai, India
Published in PloS one (01-12-2011)“…India carries one quarter of the global burden of multi-drug resistant TB (MDR-TB) and has an estimated 2.5 million people living with HIV. Despite this…”
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6
Genomic diversity among drug sensitive and multidrug resistant isolates of Mycobacterium tuberculosis with identical DNA fingerprints
Published in PloS one (12-10-2009)“…Mycobacterium tuberculosis complex (MTBC), the causative agent of tuberculosis (TB), is characterized by low sequence diversity making this bacterium one of…”
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Epidemic levels of drug resistant tuberculosis (MDR and XDR-TB) in a high HIV prevalence setting in Khayelitsha, South Africa
Published in PloS one (15-11-2010)“…Although multidrug-resistant tuberculosis (MDR-TB) is emerging as a significant threat to tuberculosis control in high HIV prevalence countries such as South…”
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Sequence Analyses of Just Four Genes To Detect Extensively Drug-Resistant Mycobacterium tuberculosis Strains in Multidrug-Resistant Tuberculosis Patients Undergoing Treatment
Published in Antimicrobial Agents and Chemotherapy (01-08-2009)“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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9
The need to accelerate access to new drugs for multidrug-resistant tuberculosis
Published in Bulletin of the World Health Organization (01-07-2015)“…Approximately half a million people are thought to develop multidrug-resistant tuberculosis annually. Barely 20% of these people currently receive recommended…”
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Multidrug-resistant tuberculosis treatment outcomes in Karakalpakstan, Uzbekistan: treatment complexity and XDR-TB among treatment failures
Published in PloS one (07-11-2007)“…A pilot programme to treat multidrug-resistant TB (MDR-TB) was implemented in Karakalpakstan, Uzbekistan in 2003. This region has particularly high levels of…”
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Risk of Acquired Drug Resistance during Short-Course Directly Observed Treatment of Tuberculosis in an Area with High Levels of Drug Resistance
Published in Clinical infectious diseases (01-06-2007)“…Background. Data on the performance of standardized short-course directly observed treatment (DOTS) of tuberculosis (TB) in areas with high levels of drug…”
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12
Serogroup X in meningococcal disease, Western Kenya
Published in Emerging infectious diseases (01-06-2007)Get full text
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13
Resistance to fluoroquinolones and second-line injectable drugs: impact on multidrug-resistant TB outcomes
Published in The European respiratory journal (01-07-2013)“…A meta-analysis for response to treatment was undertaken using individual data of multidrug-resistant tuberculosis (MDR-TB) (resistance to isoniazid and…”
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Long term efficacy of DOTS regimens for tuberculosis: systematic review
Published in BMJ (01-03-2008)“…Objective To identify published studies assessing tuberculosis recurrence after successful treatment with standard short course regimens for six months to…”
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15
The benefits and risks of mathematical modelling in tuberculosis
Published in The international journal of tuberculosis and lung disease (01-05-2014)Get full text
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Impact of Decentralized Care and the Xpert MTB/RIF Test on Rifampicin-Resistant Tuberculosis Treatment Initiation in Khayelitsha, South Africa
Published in Open forum infectious diseases (01-01-2015)“…Background. Globally, case detection and treatment access are poor for rifampicin-resistant tuberculosis (RR-TB). The Xpert MTB/RIF test has the potential to…”
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17
Emergence of Extensive Drug Resistance during Treatment for Multidrug-Resistant Tuberculosis
Published in The New England journal of medicine (27-11-2008)“…This report from Uzbekistan describes the development of fluoroquinolone-resistant and extensively drug-resistant tuberculosis during second-line treatment for…”
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embCAB sequence variation among ethambutol-resistant Mycobacterium tuberculosis isolates without embB306 mutation
Published in Journal of antimicrobial chemotherapy (01-07-2010)“…Objectives Mechanisms of resistance to ethambutol in Mycobacterium tuberculosis remain inadequately described. Although there is mounting evidence that…”
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19
Effects of aging on the responsiveness of the human cardiac sympathetic nerves to stressors
Published in Circulation (New York, N.Y.) (15-01-1995)“…Aging increases human sympathetic nervous activity at rest. Beause of the probable importance of neural stress responses in the heart as triggers for clinical…”
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Tuberculosis ethambutol resistance: Concordance between phenotypic and genotypic test results
Published in Tuberculosis (Edinburgh, Scotland) (01-11-2009)“…Summary embB 306 mutations are potential markers for detecting ethambutol resistance in clinical Mycobacterium tuberculosis isolates. However, more recently,…”
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