Search Results - "COWLEY, Hugh"

On the Design of Radical–Radical Cocrystals by Nascimento, Mitchell A., Heyer, Elodie, Clarke, Joshua J., Cowley, Hugh J., Alberola, Antonio, Stephaniuk, Nadia, Rawson, Jeremy M.

“…Formation of radical–radical cocrystals is an important step towards the design of organic ferrimagnets. We describe a simple approach to generate…”
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Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsìveness, and the late asthmatic response by Leckie, Margaret J, Brinke, Anneke ten, Khan, Jamey, Diamant, Zuzana, O'Connor, Brian J, Walls, Christine M, Mathur, Ashwini K, Cowley, Hugh C, Chung, K Fan, Djukanovic, Ratko, Hansel, Trevor T, Holgate, Stephen T, Sterk, Peter J, Barnes, Peter J

“…Interleukin-5 (IL-5) is essential for the formation of eosinophils, which are thought to have a major role in the pathogenesis of asthma and other allergic…”
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Catalytic dehydrocoupling of Me2NHBH3 with Al(NMe2)3 by Cowley, Hugh J, Holt, Mark S, Melen, Rebecca L, Rawson, Jeremy M, Wright, Dominic S

“…The catalytic dehydrocoupling reaction of Me(2)NHBH(3) with Al(NMe(2))(3) gives the dimer [Me(2)NBH(2)](2) and the chain [(Me(2)N)(2)BH], involving the…”
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Non-Innocent Ligand Effects on Low-Oxidation-State Indium Complexes by Allan, Christopher J., Cooper, Benjamin F. T., Cowley, Hugh J., Rawson, Jeremy M., Macdonald, Charles L. B.

“…Attempts to coordinate neutral ligands to low oxidation state indium centers are often hindered by disproportionation pathways that produce elemental indium…”
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On the Design of Radical–Radical Cocrystals by Nascimento, Mitchell A., Heyer, Elodie, Clarke, Joshua J., Cowley, Hugh J., Alberola, Antonio, Stephaniuk, Nadia, Rawson, Jeremy M.

“…Formation of radical–radical cocrystals is an important step towards the design of organic ferrimagnets. We describe a simple approach to generate…”
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Absorption, Disposition, and Metabolism of Rosiglitazone, a Potent Thiazolidinedione Insulin Sensitizer, in Humans by COX, P. J, RYAN, D. A, HOLLIS, F. J, HARRIS, A.-M, MILLER, A. K, VOUSDEN, M, COWLEY, H

“…Rosiglitazone is a potent peroxisome proliferator-activated receptor gamma agonist that decreases hyperglycemia by reducing insulin resistance in patients with…”
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Decreased antioxidant status and increased lipid peroxidation in patients with septic shock and secondary organ dysfunction by Goode, Helen F, Cowley, Hugh C, Walker, Barry E, Howdle, Peter D, Webster, Nigel R

“…OBJECTIVETo determine antioxidant vitamin concentrations, lipid peroxidation, and an index of nitric oxide production in patients in the intensive care unit…”
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Plasma antioxidant potential in severe sepsis: A comparison of survivors and nonsurvivors by Cowley, Hugh C, Bacon, Pamela J, Goode, Helen F, Webster, Nigel R, Jones, J. Gareth, Menon, David K

“…OBJECTIVE To determine the plasma antioxidant potential of patients in the intensive care unit (ICU) with severe sepsis and secondary organ dysfunction and…”
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C–H Bond Activation by Radical Ion Pairs Derived from R3P/Al(C6F5)3 Frustrated Lewis Pairs and N2O by Ménard, Gabriel, Hatnean, Jillian A, Cowley, Hugh J, Lough, Alan J, Rawson, Jeremy M, Stephan, Douglas W

“…Al(C6F5)3/R3P [R = tert-butyl (tBu), mesityl (Mes), naphthyl (Nap)] frustrated Lewis pairs react with N2O to form species having the formula R3P(N2O)Al(C6F5)3,…”
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Increased circulating adhesion molecule concentrations in patients with the systemic inflammatory response syndrome: a prospective cohort study by Cowley, H C, Heney, D, Gearing, A J, Hemingway, I, Webster, N R

“…To investigate the relationship between the soluble derivatives of endothelial adhesion molecules liberated by activated vascular endothelium and the…”
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Cover Picture: On the Design of Radical–Radical Cocrystals (Angew. Chem. Int. Ed. 5/2019) by Nascimento, Mitchell A., Heyer, Elodie, Clarke, Joshua J., Cowley, Hugh J., Alberola, Antonio, Stephaniuk, Nadia, Rawson, Jeremy M.

“…SOMO Wrestling Molecules of C6F5CNSSN and TEMPO radicals tangle on the Dohyō. In their Communication on page 1371, J. M. Rawson and co‐workers implement…”
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Effect of COVID-19 pandemic on missed medical appointment among adults with chronic disease conditions in Northwest Ethiopia by Tadesse Awoke Ayele, Tesfa Sewunet Alamneh, Habtewold Shibru, Malede Mequanent Sisay, Tesfahun Melese Yilma, Melkitu Fentie Melak, Telake Azale Bisetegn, Tariku Belachew, Mahteme Haile, Taye Zeru, Mezgebu Selamsew Asres, Kegnie Shitu

“…Background COVID-19 had affected the health-care-seeking behavior of people with chronic medical conditions. The impact is even worse in resource-limited…”
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Pharmacokinetics of a hematoregulatory peptide (SK&F 107647) in healthy male volunteers and in patients with colorectal or pancreatic adenocarcinoma not amenable to standard therapy by ZIA-AMIRHOSSEINI, P, HARRIS, R. Z, COWLEY, H. C, VALLE, J. W, CITERONE, D. R, BOPPANA, V. K, SCARFFE, H, WATSON, P, DAVIS, C. B

“…To describe the pharmacokinetics of SK&F 107647, a synthetic hematoregulatory peptide, in healthy volunteers and in patients with adenocarcinoma. SK&F 107647…”
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C–H Bond Activation by Radical Ion Pairs Derived from R 3 P/Al(C 6 F 5 ) 3 Frustrated Lewis Pairs and N 2 O by Ménard, Gabriel, Hatnean, Jillian A., Cowley, Hugh J., Lough, Alan J., Rawson, Jeremy M., Stephan, Douglas W.

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Titelbild: On the Design of Radical–Radical Cocrystals (Angew. Chem. 5/2019) by Nascimento, Mitchell A., Heyer, Elodie, Clarke, Joshua J., Cowley, Hugh J., Alberola, Antonio, Stephaniuk, Nadia, Rawson, Jeremy M.

“…Beim SOMO‐Ringen steigen C6F5CNSSN‐ und TEMPO‐Radikale in den Ring. In ihrer Zuschrift auf S. 1385 setzen J. M. Rawson und Mitarbeiter vorteilhafte…”
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Differential Occupancy of Somatodendritic and Postsynaptic 5HT1A Receptors by Pindolol: A Dose-Occupancy Study with [11C]WAY 100635 and Positron Emission Tomography in Humans by Martinez, Diana, Hwang, Dah-Ren, Mawlawi, Osama, Slifstein, Mark, Kent, Justine, Simpson, Norman, Parsey, Ramin V., Hashimoto, Tomoki, Huang, Yiyun, Shinn, Ann, Van Heertum, Ronald, Abi-Dargham, Anissa, Caltabiano, Stephen, Malizia, Andrea, Cowley, Hugh, Mann, J.John, Laruelle, Marc

“…Augmentation of selective serotonin reuptake inhibitors (SSRIs) therapy by the 5-HT1A receptor agent pindolol may reduce the delay between initiation of…”
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Titelbild: On the Design of Radical–Radical Cocrystals by Nascimento, Mitchell A, Heyer, Elodie, Clarke, Joshua J, Cowley, Hugh J, Alberola, Antonio, Stephaniuk, Nadia, Rawson, Jeremy M

“…Beim SOMO‐Ringen steigen C6F5CNSSN‐ und TEMPO‐Radikale in den Ring. In ihrer Zuschrift auf S. 1385 setzen J. M. Rawson und Mitarbeiter vorteilhafte…”
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An Overview of the Pharmacokinetics of Cilomilast (Ariflo®), a New, Orally Active Phosphodiesterase 4 Inhibitor, in Healthy Young and Elderly Volunteers by Zussman, Barry D., Benincosa, Lisa J., Webber, Dawn M., Clark, David J., Cowley, Hugh, Kelly, John, Murdoch, Robed D., Upward, James, Wyld, Peter, Port, Andreas, Fuder, Hermann

“…The oral pharmacokinetics of cilomilast (Ariflo®) were investtigated in five separate studies in healthy volunteers. Cilomilast was rapidly absorbed, and…”
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Positron emission tomography study of pindolol occupancy of 5-HT(1A) receptors in humans: preliminary analyses by Martinez, D, Mawlawi, O, Hwang, D R, Kent, J, Simpson, N, Parsey, R V, Hashimoto, T, Slifstein, M, Huang, Y, Van Heertum, R, Abi-Dargham, A, Caltabiano, S, Malizia, A, Cowley, H, Mann, J J, Laruelle, M

“…Preclinical studies in rodents suggest that augmentation of serotonin reuptake inhibitors (SSRIs) therapy by the 5-hydroxytryptamine(1A) (5-HT(1A)) receptor…”
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Differential Occupancy of Somatodendritic and Postsynaptic 5HT sub(1A) Receptors by Pindolol: A Dose-Occupancy Study with [ super(11)C]WAY 100635 and Positron Emission Tomography in Humans by Martinez, Diana, Hwang, Dah-Ren, Mawlawi, Osama, Slifstein, Mark, Kent, Justine, Simpson, Norman, Parsey, Ramin V, Hashimoto, Tomoki, Huang, Yiyun, Shinn, Ann, Van Heertum, Ronald, Abi-Dargham, Anissa, Caltabiano, Stephen, Malizia, Andrea, Cowley, Hugh, Mann, J John, Laruelle, Marc

“…Augmentation of selective serotonin reuptake inhibitors (SSRIs) therapy by the 5-HT sub(1A) receptor agent pindolol may reduce the delay between initiation of…”
Get full text