Search Results - "COVELLO, P. S"

Seed-Specific Over-Expression of an Arabidopsis cDNA Encoding a Diacylglycerol Acyltransferase Enhances Seed Oil Content and Seed Weight by Colette Jako, Kumar, Arvind, Yangdou Wei, Zou, Jitao, Dennis L. Barton, Giblin, E. Michael, Patrick S. Covello, Taylor, David C.

“…We recently reported the cloning and characterization of an Arabidopsis (ecotype Columbia) diacylglycerol acyltransferase cDNA (Zou et al., 1999) and found…”
Get full text

High-level semi-synthetic production of the potent antimalarial artemisinin by Paddon, C. J., Westfall, P. J., Pitera, D. J., Benjamin, K., Fisher, K., McPhee, D., Leavell, M. D., Tai, A., Main, A., Eng, D., Polichuk, D. R., Teoh, K. H., Reed, D. W., Treynor, T., Lenihan, J., Jiang, H., Fleck, M., Bajad, S., Dang, G., Dengrove, D., Diola, D., Dorin, G., Ellens, K. W., Fickes, S., Galazzo, J., Gaucher, S. P., Geistlinger, T., Henry, R., Hepp, M., Horning, T., Iqbal, T., Kizer, L., Lieu, B., Melis, D., Moss, N., Regentin, R., Secrest, S., Tsuruta, H., Vazquez, R., Westblade, L. F., Xu, L., Yu, M., Zhang, Y., Zhao, L., Lievense, J., Covello, P. S., Keasling, J. D., Reiling, K. K., Renninger, N. S., Newman, J. D.

“…Saccharomyces cerevisiae is engineered to produce high concentrations of artemisinic acid, a precursor of the artemisinin used in combination therapies for…”
Get full text

A Mutation in Human Keratin K6b Produces a Phenocopy of the K17 Disorder Pachyonychia Congenita Type 2 by Smith, Frances J. D., Jonkman, Marcel F., van Goor, Harry, Coleman, Carrie M., Covello, Seana P., Uitto, Jouni, McLean, W. H. Irwin

“…Type I and type II keratins form the heteropolymeric intermediate filament cytoskeleton, which is the main stress-bearing structure within epithelial cells…”
Get full text

Keratin 17 mutations cause either steatocystoma multiplex or pachyonychia congenita type 2 by COVELLO, S. P, SMITH, F. J. D, SMITT, J. H. S, PALLER, A. S, MUNRO, C. S, JONKMAN, M. F, UITTO, J, MCLEAN, W. H. I

“…Pachyonychia congenita type 2 (PC‐2; Jackson–Lawler syndrome) is an autosomal dominant disorder characterized by hypertrophic nail dystrophy, mild focal…”
Get full text

Alteration of Seed Fatty Acid Composition by an Ethyl Methanesulfonate-Induced Mutation in Arabidopsis thaliana Affecting Diacylglycerol Acyltransferase Activity by Vesna Katavic, Darwin W. Reed, Taylor, David C., Giblin, E. Michael, Dennis L. Barton, Zou, Jitao, Samuel L. Mac Kenzie, Patrick S. Covello, Kunst, Ljerka

“…In characterizing the enzymes involved in the formation of very long-chain fatty acids (VLCFAs) in the Brassicaceae, we have generated a series of mutants of…”
Get full text

Characterization of the Brassica napus Extraplastidial Linoleate Desaturase by Expression in Saccharomyces cerevisiae by REED, D. W, SCHÄFER, U. A, COVELLO, P. S

“…The substrate specificity and regioselectivity of the Brassica napus extraplastidial linoleate desaturase (FAD3) was investigated in vivo in a heterologous…”
Get full text

Functional expression of the extraplastidial Arabidopsis thaliana oleate desaturase gene (FAD2) in Saccharomyces cerevisiae by Covello, P.S. (National Research Council, Saskatoon, Saskatchewan, Canada.), Reed, D.W

“…The functional expression in yeast of the Arabidopsis thaliana FAD2 gene, encoding the extraplastidial oleate desaturase (1-acyl-2-olecyl-sn-glycero…”
Get full text

Characterization of the Regiochemistry and Cryptoregiochemistry of a Caenorhabditis elegans Fatty Acid Desaturase (FAT-1) Expressed in Saccharomyces cerevisiae by Meesapyodsuk, Dauenpen, Reed, Darwin W, Savile, Christopher K, Buist, Peter H, Ambrose, Stephen J, Covello, Patrick S

“…To characterize the fatty acid desaturase produced by the fat-1 gene from the nematode Caenorhabditis elegans, the functional expression of this enzyme was…”
Get full text

Silent mitochondrial and active nuclear genes for subunit 2 of cytochrome c oxidase (cox2) in soybean: evidence for RNA‐mediated gene transfer by Covello, P.S., Gray, M.W.

“…In most plants and other eukaryotes investigated, the mitochondrial genome carries the gene encoding subunit 2 of cytochrome c oxidase (cox2). In this paper,…”
Get full text

On the evolution of RNA editing by Covello, P S, Gray, M W

“…The term 'RNA editing' encompasses a variety of processes that change the primary nucleotide sequence of an RNA transcript from that of its encoding DNA. As in…”
Get more information

RNA editing in plant mitochondria by Covello, Patrick S, Gray, Michael W

“…A basic principle of molecular biology is that the primary sequence of RNA faithfully reflects the primary sequence of the DNA from which it is transcribed…”
Get full text

The diagnostic quandary of hereditary haemorrhagic telangiectasia vs. CREST syndrome by Lee, J.B., Ben‐Aviv, D., Covello, S.P.

“…The distribution and clinical appearance of the telangiectasia in the CREST syndrome (calcinosis, Raynaud’s phenomenon, oesophageal involvement, sclerodactyly,…”
Get full text

Identification and Analysis of a Gene from Calendula officinalis Encoding a Fatty Acid Conjugase by XIAO QIU, REED, Darwin W, HAIPING HONG, MACKENZIE, Samuel L, COVELLO, Patrick S

“…Two homologous cDNAs, CoFad2 and CoFac2, were isolated from a Calendula officinalis developing seed by a polymerase chain reaction-based cloning strategy. Both…”
Get full text

A novel mutation in the helix termination motif of keratin K12 in a US family with Meesmann corneal dystrophy by Coleman, Carrie M., Hannush, Sadeer, Covello, Seana P., Smith, Frances J.D., Uitto, Jouni, McLean, W.H.Irwin

“…PURPOSE: Meesmann corneal dystrophy is an autosomal dominant disorder characterized by fragility of the anterior corneal epithelium. We have previously…”
Get full text

Mutations in Keratin K9 in Kindreds with Epidermolytic Palmoplantar Keratoderma and Epidemiology in Northern Ireland by Covello, Seana P., Irvine, Alan D., McKenna, Kevin E., Munro, Colin S., Nevin, Norman C., Smith, Frances J.D., Uitto, Jouni, Irwin McLean, W.H.

“…Epidermolytic palmoplantar keratoderma (EPPK, MIM #144200) is an autosomal dominant disorder in which hyperkeratosis confined to the palms and soles is…”
Get full text

The Gene for Hypotrichosis of Marie Unna Maps between D8S258 and D8S298: Exclusion of the hr Gene by cDNA and Genomic Sequencing by van Steensel, Maurice, Smith, Frances J.D., Steijlen, Peter M., Kluijt, Irma, Stevens, Howard P., Messenger, Andrew, Kremer, Hannie, Dunnill, M. Giles S., Kennedy, Cameron, Munro, Colin S., Doherty, Valerie R., McGrath, John A., Covello, Seana P., Coleman, Carrie M., Uitto, Jouni, McLean, W. H. Irwin

“…Hypotrichosis of Marie Unna (MU) is an autosomal dominant hair-loss disorder with onset in childhood. A genomewide search for the gene was performed in a large…”
Get full text

Differences in editing at homologous sites in messenger RNAs from angiosperm mitochondria by Covello, P S, Gray, M W

“…Recent work has shown that amino acid sequence comparisons can be used to infer sites of C-to-U RNA editing in plant mitochondrial mRNAs (1). In order to test…”
Get full text

Identification of Novel Glucocorticoid-Response Elements in Human Elastin Promoter and Demonstration of Nucleotide Sequence Specificity of the Receptor Binding by Del Monaco, Magaly, Covello, Seana P., Kennedy, Susan H., Gilinger, Gwen, Litwack, Gerald, Uitto, Jouni

“…Glucocorticoids exert their action on gene expression through activation of cytoplasmic glucocorticoid receptors (GRs) that bind to glucocorticoid response…”
Get full text

Expression of meadowfoam Des5 and FAE1 genes in yeast and in transgenic soybean somatic embryos, and their roles in fatty acid modification by Marillia, Elizabeth-France, Michael Giblin, E., Covello, Patrick S., Taylor, David C.

“…Meadowfoam ( Limnanthes spp.) species are unique in that their seeds are rich in the unusual fatty acids Δ 5-eicosenoic acid (C20:1 Δ5) and the diene, C22:2…”
Get full text

Metabolism of hydroxy fatty acids in developing seeds in the genera Lesquerella (Brassicaceae) and Linum (Linaceae) by Reed, D.W. (National Research Council, Saskatoon, Saskatchewan, Canada.), Taylor, D.C, Covellol P.S

“…Members of the genus Lesquerella produce seed oil that contains a high proportion of hydroxy fatty acids (HFAs). There are three groups of Lesquerella species…”
Get full text